Sitagliptin powder

Supply API Sitagliptin powder with CAS 486460-32-6

Orukọ ọja:
Sitagliptin powder
Ipele:
Pharmaceutical grade
Awọn ohun-ini:
funfun lulú
Iṣakojọpọ:
25kg / ilu
MOQ:
1 kilo
Ibi ipamọ:Itura Gbẹ Ibi
Igbesi aye ipamọ:ọdun meji 2

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Awọn alaye

Awọn afi

Apejuwe ọja

Sitagliptin is an oral antihyperglycemic of the dipeptidyl peptidase-4 inhibitor class. This enzyme-inhibiting drug is used either alone or in combination with other oral antihyperglycemic agents for treatment of diabetes mellitus type 2.The benefit of this medicine is its fewer side effects in the control of blood glucose values. While safety is its advantage, efficacy is often challenged as it is often recommended to be combined with other agents such as metformin.

Ohun elo

Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that controls blood glucose levels by protecting and enhancing endogenous enteroglycin.Glucose-dependent insulin-releasing peptides (GIP) and glucagon-like peptide-1 (GLP-1) are enteroglycins released in response to dietary intake.

GLP-1 and GIP can increase insulin synthesis and release from islet β cells through intracellular signaling pathways. GLP-1 can also reduce glucagon secretion from islet α cells and reduce hepatic glucose production.However, both GLP-1 and GIP are rapidly metabolized by DPP-4, resulting in the loss of their insulin-promoting effect.

Awọn anfani

A ni ọpọlọpọ awọn ile-iṣelọpọ giga-giga pẹlu ifowosowopo jinlẹ, eyiti o le fun ọ ni awọn ọja to gaju ati awọn idiyele ifigagbaga. Ati pe a tun le fun awọn ẹdinwo fun awọn rira olopobobo.Ati pe a ṣe ifọwọsowọpọ pẹlu ọpọlọpọ awọn ile-iṣẹ gbigbe ẹru ẹru ọjọgbọn, le fi awọn ọja ranṣẹ lailewu ati laisiyonu si ọwọ rẹ. Akoko ifijiṣẹ jẹ nipa awọn ọjọ 3-20 lẹhin ijẹrisi isanwo.

Sipesifikesonu

Nkan	Test Standard	Testing Result
CBD	Not less than (NLT) 99.5% 99.9%
THC	Not detected	Undetected
Ayẹwo	Method HPLC calculated on the anhydrous basis limit of quotation (LOQ) 0.8ppm
Ifarahan	Iyẹfun funfun	White powder
Idanimọ	In the recorded chromatograms under the determination of the substance, retention time of the main peak of the solution should be consistent with the retention of time of the main peak of the reference solution	Ibamu
Ojuami Iyo	65~66ºC	65.5ºC
Pipadanu lori Gbigbe	NMT 1.0%	0.21%
Residual solvents	Ethanol NMT 400ppm Heptane NMT 400ppm	1.92ppm 256.0ppm
Heavy Mental	NMT 20ppm	Ibamu
Microbial Limite Test	Method: Plate Counting
Total aerobic bacteria count	NMT 1000cfu/g	Ibamu
Combined molds and yeast	NMT 100cfu/g	Ibamu
E. Coli	Not detacted per gram	Ibamu
Salmanella	Not detacted per 10 gram	Ibamu
Conclusion: Conform the testing result is qualified

Sowo ati owo sisan

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