Sitagliptin powder

Supply API Sitagliptin powder with CAS 486460-32-6

Produk Naam:
Sitagliptin powder
Graad:
Pharmaceutical grade
Eienskappe:
wit poeier
Verpakking:
25 kg/drom
MOQ:
1 kilo
Berging:Koel Droë Plek
Raklewe:2 jaar

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Besonderhede

Merkers

Produk Beskrywing

Sitagliptin is an oral antihyperglycemic of the dipeptidyl peptidase-4 inhibitor class. This enzyme-inhibiting drug is used either alone or in combination with other oral antihyperglycemic agents for treatment of diabetes mellitus type 2.The benefit of this medicine is its fewer side effects in the control of blood glucose values. While safety is its advantage, efficacy is often challenged as it is often recommended to be combined with other agents such as metformin.

Toepassing

Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that controls blood glucose levels by protecting and enhancing endogenous enteroglycin.Glucose-dependent insulin-releasing peptides (GIP) and glucagon-like peptide-1 (GLP-1) are enteroglycins released in response to dietary intake.

GLP-1 and GIP can increase insulin synthesis and release from islet β cells through intracellular signaling pathways. GLP-1 can also reduce glucagon secretion from islet α cells and reduce hepatic glucose production.However, both GLP-1 and GIP are rapidly metabolized by DPP-4, resulting in the loss of their insulin-promoting effect.

Voordele

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Spesifikasie

Item	Test Standard	Testing Result
CBD	Not less than (NLT) 99.5% 99.9%
THC	Not detected	Undetected
Toets	Method HPLC calculated on the anhydrous basis limit of quotation (LOQ) 0.8ppm
Voorkoms	Wit poeier	White powder
Identifikasie	In the recorded chromatograms under the determination of the substance, retention time of the main peak of the solution should be consistent with the retention of time of the main peak of the reference solution	Voldoen
Smeltpunt	65~66ºC	65.5ºC
Verlies op droog	NMT 1.0%	0.21%
Residual solvents	Ethanol NMT 400ppm Heptane NMT 400ppm	1.92ppm 256.0ppm
Heavy Mental	NMT 20ppm	Voldoen
Microbial Limite Test	Method: Plate Counting
Total aerobic bacteria count	NMT 1000cfu/g	Voldoen
Combined molds and yeast	NMT 100cfu/g	Voldoen
E. Coli	Not detacted per gram	Voldoen
Salmanella	Not detacted per 10 gram	Voldoen
Conclusion: Conform the testing result is qualified

Versending en betaling

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Accepted Payment Currency:USD;EUR
Aanvaarde tipe betaling: T/T, Western Union; Paypal, Handelsversekering.
Gesproke taal: Engels.

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