Sitagliptin is an oral antihyperglycemic of the dipeptidyl peptidase-4 inhibitor class. This enzyme-inhibiting drug is used either alone or in combination with other oral antihyperglycemic agents for treatment of diabetes mellitus type 2.The benefit of this medicine is its fewer side effects in the control of blood glucose values. While safety is its advantage, efficacy is often challenged as it is often recommended to be combined with other agents such as metformin.
Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that controls blood glucose levels by protecting and enhancing endogenous enteroglycin.Glucose-dependent insulin-releasing peptides (GIP) and glucagon-like peptide-1 (GLP-1) are enteroglycins released in response to dietary intake.
GLP-1 and GIP can increase insulin synthesis and release from islet β cells through intracellular signaling pathways. GLP-1 can also reduce glucagon secretion from islet α cells and reduce hepatic glucose production.However, both GLP-1 and GIP are rapidly metabolized by DPP-4, resulting in the loss of their insulin-promoting effect.
Peb muaj ntau lub Hoobkas zoo nrog kev koom tes sib sib zog nqus, uas tuaj yeem muab koj cov khoom zoo thiab cov nqi sib tw. Thiab peb tseem tuaj yeem muab cov luv nqi rau kev yuav khoom ntau.Thiab peb koom tes nrog ntau lub tuam txhab xa khoom xa tuaj, tuaj yeem xa cov khoom lag luam kom nyab xeeb thiab ntseeg nkaws rau koj txhais tes. Lub sij hawm xa tuaj yog li 3-20 hnub tom qab tau txais kev pom zoo ntawm kev them nyiaj.
Yam khoom | Test Standard | Testing Result | |
CBD | Not less than (NLT) 99.5% 99.9% | ||
THC | Not detected | Undetected | |
Assay | Method HPLC calculated on the anhydrous basis limit of quotation (LOQ) 0.8ppm | ||
Qhov tshwm sim | Dawb hmoov | White powder | |
Kev txheeb xyuas | In the recorded chromatograms under the determination of the substance, retention time of the main peak of the solution should be consistent with the retention of time of the main peak of the reference solution | Ua raws | |
Melting Point | 65~66ºC | 65.5ºC | |
Poob rau ziab | NMT 1.0% | 0.21% | |
Residual solvents | Ethanol NMT 400ppm Heptane NMT 400ppm |
1.92ppm 256.0ppm |
|
Heavy Mental | NMT 20ppm | Ua raws | |
Microbial Limite Test | Method: Plate Counting | ||
Total aerobic bacteria count | NMT 1000cfu/g | Ua raws | |
Combined molds and yeast | NMT 100cfu/g | Ua raws | |
E. Coli | Not detacted per gram | Ua raws | |
Salmanella | Not detacted per 10 gram | Ua raws | |
Conclusion: Conform the testing result is qualified |
1. Koj puas yog lub Hoobkas lossis tuam txhab lag luam?
Peb yog ib qho kev sib koom ua ke kev lag luam thiab kev lag luam, muab kev pabcuam ib-nres.OEM tuaj yeem txais.
2. Koj puas muab cov qauv? Puas yog dawb lossis ntxiv?
Cov qauv dawb.Cov qauv tus nqi thauj khoom yuav tsum tau them los ntawm koj sab.
3. Koj puas muaj daim ntawv pov thawj ntsig txog kev tswj xyuas zoo?
ISO 9001: 2008 ntawv pov thawj los xyuas kom meej qhov zoo.
4. Kuv yuav muab dab tsi kom tau txais cov lus hais?
Pls qhia peb txog cov khoom lag luam uas koj xav tau, xaj kom muaj nuj nqis, chaw nyob thiab cov kev xav tau tshwj xeeb.Cov lus hais yuav ua rau koj siv sijhawm.
5. Hom kev them nqi twg koj nyiam? Cov nqe lus twg raug lees txais?
Txais Cov Lus Cog Tseg: FOB, CFR, CIF, EXW;
Accepted Payment Currency:USD;EUR
Hom Kev Them Nyiaj: T / T, Western Union; Paypal, Trade Assurance.
Lus Hais: Lus Askiv.
Cov khoom qeb