Sitagliptin is an oral antihyperglycemic of the dipeptidyl peptidase-4 inhibitor class. This enzyme-inhibiting drug is used either alone or in combination with other oral antihyperglycemic agents for treatment of diabetes mellitus type 2.The benefit of this medicine is its fewer side effects in the control of blood glucose values. While safety is its advantage, efficacy is often challenged as it is often recommended to be combined with other agents such as metformin.
Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that controls blood glucose levels by protecting and enhancing endogenous enteroglycin.Glucose-dependent insulin-releasing peptides (GIP) and glucagon-like peptide-1 (GLP-1) are enteroglycins released in response to dietary intake.
GLP-1 and GIP can increase insulin synthesis and release from islet β cells through intracellular signaling pathways. GLP-1 can also reduce glucagon secretion from islet α cells and reduce hepatic glucose production.However, both GLP-1 and GIP are rapidly metabolized by DPP-4, resulting in the loss of their insulin-promoting effect.
Manana orinasa avo lenta maro miaraka amin'ny fiaraha-miasa lalina, izay afaka manome anao vokatra avo lenta sy ny vidiny mifaninana. Ary afaka manome fihenam-bidy ho an'ny fividianana betsaka ihany koa izahay.Ary miara-miasa amin'ny orinasa mpitatitra entana matihanina maro izahay, afaka manatitra vokatra soa aman-tsara sy milamina amin'ny tananao. Delivery fotoana dia tokony ho 3-20 andro aorian'ny fanamafisana ny fandoavam-bola.
zavatra | Test Standard | Testing Result | |
CBD | Not less than (NLT) 99.5% 99.9% | ||
THC | Not detected | Undetected | |
sahy miteny | Method HPLC calculated on the anhydrous basis limit of quotation (LOQ) 0.8ppm | ||
Bika Aman 'endrika | Vovoka fotsy | White powder | |
Famantarana | In the recorded chromatograms under the determination of the substance, retention time of the main peak of the solution should be consistent with the retention of time of the main peak of the reference solution | mifanaraka | |
Tarehin-tsetroka | 65~66ºC | 65.5ºC | |
Fatiantoka amin'ny fanamainana | NMT 1.0% | 0.21% | |
Residual solvents | Ethanol NMT 400ppm Heptane NMT 400ppm |
1.92ppm 256.0ppm |
|
Heavy Mental | NMT 20ppm | mifanaraka | |
Microbial Limite Test | Method: Plate Counting | ||
Total aerobic bacteria count | NMT 1000cfu/g | mifanaraka | |
Combined molds and yeast | NMT 100cfu/g | mifanaraka | |
E. Coli | Not detacted per gram | mifanaraka | |
Salmanella | Not detacted per 10 gram | mifanaraka | |
Conclusion: Conform the testing result is qualified |
1. Orinasa ve ianao sa orinasa mpivarotra?
Izahay dia compnay mampiditra ny indostria sy ny varotra, manome serivisy tokana. Azo ekena ny OEM.
2. Manome santionany ve ianao? Maimaimpoana ve sa fanampiny?
Santionany maimaim-poana.Ny sandan'ny entana santionany dia mila aloa eo anilanao.
3. Manana taratasy fanamarinana mifandraika amin'ny fanaraha-maso kalitao ve ianao?
ISO 9001: 2008 fanamarinana mba hiantohana ny kalitao.
4. Inona no tokony homeko mba hahazoana teny nindramina?
Pls ampahafantaro anay ny karazana vokatra ilainao, ny habetsaky ny baiko, ny adiresy ary ny fepetra takiana manokana.
5. Inona no fomba fandoavam-bola tianao? Karazana fepetra inona no ekena?
Fepetra fanaterana ekena: FOB, CFR, CIF, EXW;
Accepted Payment Currency:USD;EUR
Karazana fandoavam-bola ekena: T / T, Western Union; Paypal, Trade Assurance.
Fiteny ampiasaina: Anglisy.
Ny sokajy vokatra