Sitagliptin is an oral antihyperglycemic of the dipeptidyl peptidase-4 inhibitor class. This enzyme-inhibiting drug is used either alone or in combination with other oral antihyperglycemic agents for treatment of diabetes mellitus type 2.The benefit of this medicine is its fewer side effects in the control of blood glucose values. While safety is its advantage, efficacy is often challenged as it is often recommended to be combined with other agents such as metformin.
Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that controls blood glucose levels by protecting and enhancing endogenous enteroglycin.Glucose-dependent insulin-releasing peptides (GIP) and glucagon-like peptide-1 (GLP-1) are enteroglycins released in response to dietary intake.
GLP-1 and GIP can increase insulin synthesis and release from islet β cells through intracellular signaling pathways. GLP-1 can also reduce glucagon secretion from islet α cells and reduce hepatic glucose production.However, both GLP-1 and GIP are rapidly metabolized by DPP-4, resulting in the loss of their insulin-promoting effect.
He maha nga wheketere kounga teitei me te mahi tahi, ka taea e koe te whakarato i nga hua o te kounga teitei me nga utu whakataetae. Ka taea hoki e matou te tuku utu mo nga hokonga nui.A ka mahi tahi matou me te maha o nga kamupene kawe utanga ngaio, ka taea te tuku hua ma te humarie me te pai ki o ringaringa. Ko te wa tuku mo nga ra 3-20 i muri i te whakapumautanga o te utu.
Tūemi | Test Standard | Testing Result | |
CBD | Not less than (NLT) 99.5% 99.9% | ||
THC | Not detected | Undetected | |
Te whakamatautau | Method HPLC calculated on the anhydrous basis limit of quotation (LOQ) 0.8ppm | ||
Te ahua | Te paura ma | White powder | |
Tautuhinga | In the recorded chromatograms under the determination of the substance, retention time of the main peak of the solution should be consistent with the retention of time of the main peak of the reference solution | Ka tutuki | |
Iwi Whakarewa | 65~66ºC | 65.5ºC | |
Ngaronga i te whakamaroke | NMT 1.0% | 0.21% | |
Residual solvents | Ethanol NMT 400ppm Heptane NMT 400ppm |
1.92ppm 256.0ppm |
|
Heavy Mental | NMT 20ppm | Ka tutuki | |
Microbial Limite Test | Method: Plate Counting | ||
Total aerobic bacteria count | NMT 1000cfu/g | Ka tutuki | |
Combined molds and yeast | NMT 100cfu/g | Ka tutuki | |
E. Coli | Not detacted per gram | Ka tutuki | |
Salmanella | Not detacted per 10 gram | Ka tutuki | |
Conclusion: Conform the testing result is qualified |
1. He wheketere koe, he kamupene hokohoko ranei?
He kamupene matou e whakauru ana i te ahumahi me te hokohoko, e whakarato ana i te ratonga kotahi-mutu. Ka taea e OEM te whakaae.
2. Kei te whakarato koe i nga tauira? He kore utu, he taapiri ranei?
Ko nga tauira kore utu.Ko te utu utauta a te tauira me utu e to taha.
3. Kei a koe etahi tiwhikete e pa ana ki te mana kounga?
ISO 9001: Tiwhikete 2008 hei whakarite i te kounga.
4. He aha te mea me whakarato e au ki te tiki korero?
Pls whakamohio mai ki a matou mo te momo hua e hiahiatia ana e koe, te rahinga ota, te wahitau me nga whakaritenga motuhake.Ka mahia te korero mo to tohutoro i te waa.
5. He aha te ahua o te tikanga utu e pai ana koe? He aha nga momo tikanga e whakaaetia ana?
Nga Tikanga Tukunga Whakaaetia: FOB,CFR,CIF,EXW;
Accepted Payment Currency:USD;EUR
Momo Utu Whakaae: T / T, Western Union; Paypal, Tauhokohoko Tauhokohoko.
Te Reo Korero:Maori.
Nga waahanga hua