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Sitagliptin powder

Supply API Sitagliptin powder with CAS 486460-32-6

 

  • Lebitso la sehlahisoa:

    Sitagliptin powder

  • Kereiti:

    Pharmaceutical grade

  • Thepa:

    phofo e tšoeu

  • Ho paka:

    25kg / moropa

  • MOQ:

    1 kilo

  • Polokelo:Cool Dry Place
  • Shelf bophelo:lilemo tse 2


Lintlha

Li-tag

Tlhaloso ea Sehlahisoa

Sitagliptin is an oral antihyperglycemic of the dipeptidyl peptidase-4  inhibitor class. This enzyme-inhibiting drug is used either alone or in combination with other oral antihyperglycemic agents for treatment of diabetes mellitus type 2.The benefit of this medicine is its fewer side effects in the control of blood glucose values. While safety is its advantage, efficacy is often challenged as it is often recommended to be combined with other agents such as metformin.

Kopo

Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that controls blood glucose levels by protecting and enhancing endogenous enteroglycin.Glucose-dependent insulin-releasing peptides (GIP) and glucagon-like peptide-1 (GLP-1) are enteroglycins released in response to dietary intake.

GLP-1 and GIP can increase insulin synthesis and release from islet β cells through intracellular signaling pathways. GLP-1 can also reduce glucagon secretion from islet α cells and reduce hepatic glucose production.However, both GLP-1 and GIP are rapidly metabolized by DPP-4, resulting in the loss of their insulin-promoting effect.

 

Melemo

Re na le lifeme tse ngata tsa boleng bo holimo tse nang le tšebelisano e tebileng, tse ka u fang lihlahisoa tsa boleng bo holimo le litheko tsa tlholisano. Hape re ka fana ka litheolelo bakeng sa ho reka ka bongata.'Me re sebelisana le lik'hamphani tse ngata tsa litsebi tse tsamaisang thepa, li ka isa lihlahisoa ka mokhoa o sireletsehileng le ka thelelo matsohong a hau. Nako ea ho fana e ka ba matsatsi a 3-20 ka mor'a hore ho netefatsoe tefo.

 

Tlhaloso
Ntho Test Standard Testing Result
CBD Not less than (NLT) 99.5% 99.9%
THC Not detected Undetected
Tlhahlobo Method HPLC calculated on the anhydrous basis limit of quotation (LOQ) 0.8ppm
Ponahalo Phofo e tšoeu White  powder
Boitsebiso In the recorded chromatograms under the determination of the substance, retention time of the main peak of the solution should be consistent with the retention of time of the main peak of the reference solution E lumellana
Melting Point 65~66ºC 65.5ºC
Tahlehelo ka ho Omisa NMT 1.0% 0.21%
Residual solvents Ethanol NMT 400ppm
Heptane NMT 400ppm
1.92ppm
256.0ppm
Heavy Mental NMT 20ppm E lumellana
Microbial Limite Test Method: Plate Counting   
Total aerobic bacteria count NMT 1000cfu/g E lumellana
Combined molds and yeast NMT 100cfu/g E lumellana
E. Coli Not detacted per gram E lumellana
Salmanella Not detacted per 10 gram E lumellana
Conclusion: Conform the testing result is qualified

 

Ho romella le ho lefa


 

LBH

1. Na u feme kapa k'hamphani ea khoebo?
Re komnay e kopanyang indasteri le khoebo, ho fana ka ts'ebeletso e le 'ngoe.OEM e ka amoheloa.

2. O fana ka mehlala? Na ke mahala kapa ho feta?
Mehlala ea mahala. Tefiso ea thepa ea sampole e hloka ho lefuoa ka lehlakore la hau.

3. O na le litifikeiti tse amanang le taolo ea boleng?
Setifikeiti sa ISO 9001:2008 ho netefatsa boleng.

4. Ke fane ka eng ho fumana khotheishene?
Pls re tsebise ka mofuta oa sehlahisoa seo u se hlokang, bongata ba odara, aterese le litlhoko tse ikhethileng. Khotheishene e tla etsoa bakeng sa referense ea hau ka nako.

5. U khetha mofuta ofe oa mokhoa oa ho lefa? Ke mantsoe a mofuta ofe a amoheloang?
Melao e Amoheletsoeng ea Thomello: FOB,CFR,CIF,EXW;
Accepted Payment Currency:USD;EUR
Mofuta oa Tefo o Amoheletsoeng: T/T, Western Union; Paypal, Tiisetso ea Khoebo.
Puo e Builoeng: Senyesemane.

 

Haeba u thahasella lihlahisoa tsa rona, u ka khetha ho siea lintlha tsa hau mona, 'me re tla buisana le uena haufinyane.


Ngola molaetsa wa hao mona mme o re romele wona