Reserpine

Reserpine yog ib qho indole alkaloid siv hauv kev kho mob ntshav siab thiab mob hlwb. Nws yog Ameslikas muab rho tawm los ntawm cov nroj tsuag Serpentine. Niaj hnub no, vim muaj kev phiv ntau dua thiab cov tshuaj tshiab zoo dua ntawm kev ua lag luam, reserpine tsis yog thawj qhov kev xaiv rau kev kho mob. Catecholamines (monoamine neurotransmitters) ua lub luag haujlwm tseem ceeb hauv kev tswj lub plawv dhia, myocardial contractile force thiab peripheral resistance, thiab reserpine exerts nws antihypertensive nyhuv los ntawm kev noj catecholamines los ntawm peripheral sympathetic paj hlwb xaus.

Soluble hauv chloroform, dichloromethane, glacial acetic acid, tuaj yeem yaj hauv benzene, ethyl acetate, me ntsis soluble hauv acetone, methanol, ethanol, ether, acetic acid thiab citric acid daws. Kev daws ntawm reserpine hloov daj tom qab ib lub sij hawm ntawm lub sij hawm, thiab muaj fluorescence tseem ceeb, thiab cov fluorescence yog txhim kho tom qab acid ntxiv thiab raug. Reserpine yog lub hauv paus tsis muaj zog. Reserpine tuaj yeem txo cov ntshav siab thiab lub plawv dhia qeeb. Nws qhov kev ua yog qeeb, me me thiab kav ntev. Nws muaj ib tug ntev-ntev calming nyhuv ntawm lub hauv paus paj hlwb thiab yog ib tug zoo sedative.

Reserpine feem ntau cuam tshuam rau kev nce ntawm norepinephrine mus rau hauv cov hlab ntsha hauv cov hlab ntsha hauv cov hlab ntsha, ua rau nws raug degraded los ntawm monoamine oxidase thiab depleting qhov cia ntawm norepinephrine, yog li impairing kev sib kis ntawm sympathetic paj hlwb impulses. Qhov no ua rau vascular dilation, txo cov ntshav siab, thiab txo lub plawv dhia. Lub hauv paus paj hlwb sedation thiab inhibition yuav tshwm sim ntawm reserpine nkag mus rau hauv lub hlwb thiab depleting lub hauv paus catecholamine cia. Cov nyhuv hypotensive tshwm sim hauv 1 teev tom qab txhaj tshuaj. Cov nyhuv antihypertensive ntawm kev kho qhov ncauj pib kwv yees li 1 lub lis piam tom qab kev tswj hwm thiab ncav cuag nws cov txiaj ntsig siab tshaj 2-3 lub lis piam tom qab. Cov nyhuv tshwm sim rau 3-4 lub lis piam tom qab txiav kev kho mob.

Peb muaj ntau lub Hoobkas zoo nrog kev koom tes sib sib zog nqus, uas tuaj yeem muab koj cov khoom zoo thiab cov nqi sib tw. Thiab peb tseem tuaj yeem muab cov luv nqi rau kev yuav khoom ntau.Thiab peb koom tes nrog ntau lub tuam txhab xa khoom xa tuaj, tuaj yeem xa cov khoom lag luam kom nyab xeeb thiab ntseeg nkaws rau koj txhais tes. Lub sij hawm xa tuaj yog li 3-20 hnub tom qab tau txais kev pom zoo ntawm kev them nyiaj.

Kev sib txuam tshuaj
Cov tshuaj loog dav dav tuaj yeem txhim kho cov nyhuv antihypertensive ntawm reserpine. Ua ke nrog ethanol lossis central paj hlwb inhibitors, lub hauv paus inhibitory tuaj yeem ua rau hnyav dua.
1. ua ke nrog lwm cov tshuaj antihypertensive lossis diuretics tuaj yeem ntxiv dag zog rau cov nyhuv antihypertensive, cov koob tshuaj yuav tsum tau hloov kho; Ua ke nrog β-blocker, cov nyhuv tom kawg tuaj yeem txhim kho;
2. ua ke nrog digitalis lossis quinidine, koob tshuaj loj tuaj yeem ua rau arrhythmia;
3. ua ke nrog levodopa tuaj yeem ua rau dopamine depletion, ua rau Parkinson tus kab mob;
4. ua ke nrog indirect adrenergic tshuaj xws li ephedrine, amphetamine, thiab lwm yam., yuav ua rau catecholamine cia depletion, inhibit cov nyhuv ntawm cov tshuaj adrenergic;
5. ua ke nrog cov tshuaj adrenergic ncaj qha xws li epinephrine, isoproterenol, norepinephrine, mehydroxyamine, deoxyadrenalin, thiab lwm yam, tuaj yeem ua rau nws cov nyhuv ntev;
6. ua ke nrog tricyclic antidepressants, cov teebmeem ntawm reserpine thiab antidepressants tsis muaj zog;
7. barbiturates tuaj yeem ntxiv dag zog rau lub hauv paus sedative nyhuv ntawm reserpine.

Tshuaj overdose
Reserpine tsis muaj cov tshuaj tiv thaiv tshwj xeeb, tsis tuaj yeem tshem tawm los ntawm kev lim ntshav, kev kho mob yog cov tsos mob thiab kev txhawb nqa kev kho mob. Kev siv tshuaj ntau dhau ua rau ua pa nyuaj siab, coma, ntshav siab qis, convulsions, thiab hypothermia. Nyob rau lub sijhawm no, plab hnyuv yuav tsum tau noj kom ntuav, txawm tias tom qab ob peb teev ntawm cov tshuaj. Cov neeg mob uas muaj ntshav siab hnyav tau muab tso rau hauv qhov chaw dag, lawv ob txhais taw tau tsa, thiab cov tshuaj epinephrine ncaj qha tau ua tib zoo tswj hwm los txhawb cov ntshav siab. Kev nqus pa oxygen thiab ua pa tawm dag zog tau muab rau cov neeg mob ua pa nyuaj. Anticholinergic tshuaj kho cov tsos mob ntawm plab hnyuv; Thiab txhim kho lub cev qhuav dej, electrolyte tsis txaus, lub siab tsis nco qab, thiab hypotension. Cov neeg mob yuav tsum tau soj ntsuam tsawg kawg yog 72 teev vim hais tias reserpine ua haujlwm ntev. Ntshav siab kom txaus siab.

1. Koj puas yog lub Hoobkas lossis tuam txhab lag luam?
Peb yog ib qho kev sib koom ua ke kev lag luam thiab kev lag luam, muab kev pabcuam ib-nres.OEM tuaj yeem txais.

2. Koj puas muab cov qauv? Puas yog dawb lossis ntxiv?
Cov qauv dawb.Cov qauv tus nqi thauj khoom yuav tsum tau them los ntawm koj sab.

3. Koj puas muaj daim ntawv pov thawj ntsig txog kev tswj xyuas zoo?
ISO 9001: 2008 ntawv pov thawj los xyuas kom meej qhov zoo.

4. Kuv yuav muab dab tsi kom tau txais cov lus hais?
Pls qhia peb txog cov khoom lag luam uas koj xav tau, xaj kom muaj nuj nqis, chaw nyob thiab cov kev xav tau tshwj xeeb.Cov lus hais yuav ua rau koj siv sijhawm.

5. Hom kev them nqi twg koj nyiam? Cov nqe lus twg raug lees txais?
Txais Cov Lus Cog Tseg: FOB, CFR, CIF, EXW;
Txais Nyiaj Them Nqi: USD;
Hom Kev Them Nyiaj: T / T, Western Union; Paypal, Trade Assurance.
Lus Hais: Lus Askiv.