Sirolimus Rapamycin Powder

Pharmaceutical Grade Pure 99% Sirolimus Rapamycin Powder CAS 53123-88-9

Orukọ ọja:
Sirolimus Rapamycin Powder
Ipele:
Pharmaceutical grade
Awọn ohun-ini:
funfun lulú
Iṣakojọpọ:
25kg / ilu
MOQ:
1 kilo
Ibi ipamọ:Itura Gbẹ Ibi
Igbesi aye ipamọ:ọdun meji 2

Kan si Bayi PDF gbaa lati ayelujara

Awọn alaye

Awọn afi

Apejuwe ọja

Rapamycin is produced by the soil bacterium Streptomyces hygroscopicus. The drug's name comes from Rapa Nui, the indigenous name of Easter Island, where the compound was originally discovered in soil samples in the 1970s.

Sirolimus, also known as rapamycin, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection and treat a rare lung disease called lymphangioleiomyomatosis. It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants.

Ohun elo

Rapamycin is a triene macrolide antibiotic, which demonstrates anti-fungal, anti-inflammatory, anti-tumor and immunosuppressive properties. Rapamycin has been shown to block T-cell activation and proliferation, as well as, the activation of p70 S6 kinase and exhibits strong binding to FK-506 binding proteins.

Rapamycin also inhibits the activity of the protein, mTOR, (mammalian target of rapamycin) which functions in a signaling pathway to promote tumor growth. Rapamycin binds to a receptor protein (FKBP12) and the rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signaling pathway.

Awọn anfani

A ni ọpọlọpọ awọn ile-iṣelọpọ giga-giga pẹlu ifowosowopo jinlẹ, eyiti o le fun ọ ni awọn ọja to gaju ati awọn idiyele ifigagbaga. Ati pe a tun le fun awọn ẹdinwo fun awọn rira olopobobo.Ati pe a ṣe ifọwọsowọpọ pẹlu ọpọlọpọ awọn ile-iṣẹ gbigbe ẹru ẹru ọjọgbọn, le fi awọn ọja ranṣẹ lailewu ati laisiyonu si ọwọ rẹ. Akoko ifijiṣẹ jẹ nipa awọn ọjọ 3-20 lẹhin ijẹrisi isanwo.

Sipesifikesonu

ITEM	PATAKI	RESULT	METHOD
Ifarahan	White powder, neutral odor, highly hygroscopic	Ni ibamu	Visual
Idanimọ	Standard solution and test solution same spot,RF	Ni ibamu	TLC
Specific Optical	-2.4°~ -2.8°	-2.72°
Heavy metals (as PB)	≤10ppm	Ni ibamu	AAS
Sulfate (SO4)	≤0.02%	Ni ibamu	Colorimetry
Chloride (Cl)	≤0.02%	Ni ibamu	Colorimetry
Phosphate Ion (P)	≤5ppm	Ni ibamu	Colorimetry
Residual solvent(ethanol)	≤1.0%	Ni ibamu	HS-GC
pH	4.5~7.0	5.10
Related substance	Spot not bigger than standard solution spot	No spot	TLC
Water Content	≤2%	0.26%	KF
Assay (dried basis)	98.0%--102.0%	99.48%	Potentiometric titration
Assay (dried basis)	98.5%--100%	99.2%	HPLC

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