Produktuaren Deskribapena
Rapamycin is produced by the soil bacterium Streptomyces hygroscopicus. The drug's name comes from Rapa Nui, the indigenous name of Easter Island, where the compound was originally discovered in soil samples in the 1970s.
Sirolimus, also known as rapamycin, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection and treat a rare lung disease called lymphangioleiomyomatosis. It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants.
Aplikazio
Rapamycin is a triene macrolide antibiotic, which demonstrates anti-fungal, anti-inflammatory, anti-tumor and immunosuppressive properties. Rapamycin has been shown to block T-cell activation and proliferation, as well as, the activation of p70 S6 kinase and exhibits strong binding to FK-506 binding proteins.
Rapamycin also inhibits the activity of the protein, mTOR, (mammalian target of rapamycin) which functions in a signaling pathway to promote tumor growth. Rapamycin binds to a receptor protein (FKBP12) and the rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signaling pathway.
Abantailak
Kalitate handiko lantegi asko ditugu lankidetza sakonarekin, kalitate handiko produktuak eta prezio lehiakorrak eskain diezazkizuten. Eta ontziratu gabeko erosketetarako deskontuak ere eman ditzakegu. Eta merkantzien bidalketa-enpresa profesional askorekin lankidetzan aritzen gara, produktuak segurtasunez eta leunki entregatu ditzakegu zure eskuetara. Bidalketa-epea 3-20 egun ingurukoa da ordainketa baieztatu eta gero.
Zehaztapena
ITEM |
ZEHATZA |
RESULT |
METHOD |
Itxura |
White powder, neutral odor, highly hygroscopic |
Konforme |
Visual |
Identifikazioa |
Standard solution and test solution same spot,RF |
Konforme |
TLC |
Specific Optical |
-2.4°~ -2.8° |
-2.72° |
|
Heavy metals (as PB) |
≤10ppm |
Konforme |
AAS |
Sulfate (SO4) |
≤0.02% |
Konforme |
Colorimetry |
Chloride (Cl) |
≤0.02% |
Konforme |
Colorimetry |
Phosphate Ion (P) |
≤5ppm |
Konforme |
Colorimetry |
Residual solvent(ethanol) |
≤%1,0 |
Konforme |
HS-GC |
pH |
4.5~7.0 |
5.10 |
|
Related substance |
Spot not bigger than standard solution spot |
No spot |
TLC |
Water Content |
≤2% |
0.26% |
KF |
Assay (dried basis) |
98.0%--102.0% |
99.48% |
Potentiometric titration |
Assay (dried basis) |
98.5%--100% |
99.2% |
HPLC |
Bidalketa eta ordainketa

ohiko galderak
1. Fabrika edo merkataritza-enpresa bat al zara?
Industria eta merkataritza integratzen dituen enpresa bat gara, zerbitzu bakarra eskaintzen duena. OEM onar liteke.
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