Sirolimus Rapamycin Powder

Pharmaceutical Grade Pure 99% Sirolimus Rapamycin Powder CAS 53123-88-9

Product name:
Sirolimus Rapamycin Powder
Grade:
Pharmaceutical grade
Properties:
white powder
Packing:
25kg/drum
MOQ:
1 kilo
Storage:Cool Dry Place
Shelf life:2 years

CONTACT NOW PDF DOWNLOAD

Details

Tags

Product Description

Rapamycin is produced by the soil bacterium Streptomyces hygroscopicus. The drug's name comes from Rapa Nui, the indigenous name of Easter Island, where the compound was originally discovered in soil samples in the 1970s.

Sirolimus, also known as rapamycin, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection and treat a rare lung disease called lymphangioleiomyomatosis. It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants.

Application

Rapamycin is a triene macrolide antibiotic, which demonstrates anti-fungal, anti-inflammatory, anti-tumor and immunosuppressive properties. Rapamycin has been shown to block T-cell activation and proliferation, as well as, the activation of p70 S6 kinase and exhibits strong binding to FK-506 binding proteins.

Rapamycin also inhibits the activity of the protein, mTOR, (mammalian target of rapamycin) which functions in a signaling pathway to promote tumor growth. Rapamycin binds to a receptor protein (FKBP12) and the rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signaling pathway.

Advantages

We have many high-quality factories with deep cooperation, which can provide you with high quality products and competitive prices. And we can also give discounts for bulk purchases.And we cooperate with many professional freight forwarding companies, can deliver products safely and smoothly to your hands. Delivery time is about 3-20 days after confirmation of payment.

Specification

ITEM	SPECIFICATION	RESULT	METHOD
Appearance	White powder, neutral odor, highly hygroscopic	Conforms	Visual
Identification	Standard solution and test solution same spot,RF	Conforms	TLC
Specific Optical	-2.4°~ -2.8°	-2.72°
Heavy metals (as PB)	≤10ppm	Conforms	AAS
Sulfate (SO4)	≤0.02%	Conforms	Colorimetry
Chloride (Cl)	≤0.02%	Conforms	Colorimetry
Phosphate Ion (P)	≤5ppm	Conforms	Colorimetry
Residual solvent(ethanol)	≤1.0%	Conforms	HS-GC
pH	4.5~7.0	5.10
Related substance	Spot not bigger than standard solution spot	No spot	TLC
Water Content	≤2%	0.26%	KF
Assay (dried basis)	98.0%--102.0%	99.48%	Potentiometric titration
Assay (dried basis)	98.5%--100%	99.2%	HPLC

Shipping and payment

FAQ

1. Are you a factory or a trading company?
We are a compnay integrating industry and trade,providing one-stop service.OEM could be accepted.

2. Do you provide samples? Is it free or extra?
Free samples.The sample's freight fee need to be paid by your side.

3. Do you have any certificates related to quality control?
ISO 9001:2008 certification to ensure quality.

4. What should I provide to get a quotation?
Pls inform us of the product type which you need,order quantity,address and specific requirements.The quotation will be made for your reference in time.

5. What kind of payment method do you prefer? What kind of terms are accepted?
Accepted Delivery Terms: FOB,CFR,CIF,EXW;
Accepted Payment Currency:USD;EUR
Accepted Payment Type: T/T,Western Union; Paypal,Trade Assurance.
Language Spoken:English.

If you are interested in our products, you can choose to leave your information here, and we will be in touch with you shortly.

Write your message here and send it to us

Products categories

News Exhibition