Sirolimus Rapamycin Powder

Pharmaceutical Grade Pure 99% Sirolimus Rapamycin Powder CAS 53123-88-9

Product name:
Sirolimus Rapamycin Powder
Giredhi:
Pharmaceutical grade
Properties:
hupfu chena
Packing:
25kg / chigubhu
MOQ:
1 kilo
Kuchengeta:Nzvimbo Yakaoma yakaoma
Sherufu hupenyu:2 years

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Product Description

Rapamycin is produced by the soil bacterium Streptomyces hygroscopicus. The drug's name comes from Rapa Nui, the indigenous name of Easter Island, where the compound was originally discovered in soil samples in the 1970s.

Sirolimus, also known as rapamycin, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection and treat a rare lung disease called lymphangioleiomyomatosis. It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants.

Application

Rapamycin is a triene macrolide antibiotic, which demonstrates anti-fungal, anti-inflammatory, anti-tumor and immunosuppressive properties. Rapamycin has been shown to block T-cell activation and proliferation, as well as, the activation of p70 S6 kinase and exhibits strong binding to FK-506 binding proteins.

Rapamycin also inhibits the activity of the protein, mTOR, (mammalian target of rapamycin) which functions in a signaling pathway to promote tumor growth. Rapamycin binds to a receptor protein (FKBP12) and the rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signaling pathway.

Zvakanakira

Tine mafekitori akawanda emhando yepamusoro nekubatana kwakadzama, ayo anogona kukupa zvigadzirwa zvemhando yepamusoro nemitengo yemakwikwi. Uye isu tinogonawo kupa zvidzikiso pakutenga kwakawanda. Uye isu tinobatirana nemakambani mazhinji ehunyanzvi ekutakura zvinhu, anogona kuendesa zvigadzirwa zvakachengeteka uye zvakanaka kumaoko ako. Nguva yekutumira inenge 3-20 mazuva mushure mekusimbiswa kwekubhadhara.

Tsanangudzo

ITEM	KUTAURA	RESULT	METHOD
Chitarisiko	White powder, neutral odor, highly hygroscopic	Conforms	Visual
Identification	Standard solution and test solution same spot,RF	Conforms	TLC
Specific Optical	-2.4°~ -2.8°	-2.72°
Heavy metals (as PB)	≤10ppm	Conforms	AAS
Sulfate (SO4)	≤0.02%	Conforms	Colorimetry
Chloride (Cl)	≤0.02%	Conforms	Colorimetry
Phosphate Ion (P)	≤5ppm	Conforms	Colorimetry
Residual solvent(ethanol)	≤1.0%	Conforms	HS-GC
pH	4.5~7.0	5.10
Related substance	Spot not bigger than standard solution spot	No spot	TLC
Water Content	≤2%	0.26%	KF
Assay (dried basis)	98.0%--102.0%	99.48%	Potentiometric titration
Assay (dried basis)	98.5%--100%	99.2%	HPLC

Kutumira uye kubhadhara

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3. Iwe une chero zvitupa zvine chekuita nekutonga kwemhando?
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5. Ndeipi nzira yekubhadhara yaunoda? Ndeapi mazwi anogamuchirwa?
Mitemo Yekutumira Inogamuchirwa: FOB, CFR, CIF, EXW;
Accepted Payment Currency:USD;EUR
Rudzi rwekubhadhara rwakagamuchirwa: T / T, Western Union; Paypal, Trade Assurance.
Mutauro Unotaurwa:Chirungu.

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