2-Propylpentanoic acid CAS 99-66-1

valproicacid (VPA) is a broad-spectrum antiepileptic drug in clinical first-line, which has a good effect on various types of epilepsy and concurrent epileptoid convulsions. The metabolism of valproic acid has large individual differences, and its therapeutic window is narrow, and it interacts with a variety of drugs, which often requires therapeutic monitoring. The effective blood concentration range is 50-100 μg/mL. As early as 1882, Professor Beverley Burton of France synthesized valproic acid in his laboratory. Valproic acid is a colorless liquid at room temperature, and since pharmacological studies have shown that this compound has no pharmacological effect, valproic acid has always been a solvent commonly used in the laboratory. If the drug is insoluble to water, valproic acid will be used instead of the solvent to dissolve the drug.

Colorless liquid. Boiling point 221℃, relative density 1.1 (24.5/4℃), refractive index 1.4250, flash point 111℃. Insoluble in water.
The product is salt with sodium hydroxide solution to obtain a broad spectrum anti-epileptic melting drug sodium valproate, also known as anti-epilepsy.
- It can also be used as a modifier to improve the properties of polyesters, plastics and coatings.

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