valproicacid (VPA) is a broad-spectrum antiepileptic drug in clinical first-line, which has a good effect on various types of epilepsy and concurrent epileptoid convulsions. The metabolism of valproic acid has large individual differences, and its therapeutic window is narrow, and it interacts with a variety of drugs, which often requires therapeutic monitoring. The effective blood concentration range is 50-100 μg/mL. As early as 1882, Professor Beverley Burton of France synthesized valproic acid in his laboratory. Valproic acid is a colorless liquid at room temperature, and since pharmacological studies have shown that this compound has no pharmacological effect, valproic acid has always been a solvent commonly used in the laboratory. If the drug is insoluble to water, valproic acid will be used instead of the solvent to dissolve the drug.
Colorless liquid. Boiling point 221℃, relative density 1.1 (24.5/4℃), refractive index 1.4250, flash point 111℃. Insoluble in water.
The product is salt with sodium hydroxide solution to obtain a broad spectrum anti-epileptic melting drug sodium valproate, also known as anti-epilepsy.
- It can also be used as a modifier to improve the properties of polyesters, plastics and coatings.
Mir hu vill qualitativ héichwäerteg Fabriken mat déif Zesummenaarbecht, déi Iech mat héichqualitativen Produkter a kompetitive Präisser ubidden. A mir kënnen och Remise fir bulk Akeef ginn.A mir kooperéieren mat ville berufflech Gidderween Expeditioun Betriber, kënne Produite sécher a glat op Är Hänn liwweren. D'Liwwerzäit ass ongeféier 3-20 Deeg no der Bestätegung vun der Bezuelung.
Molecular Formula | C8H16O2 |
Molar Mass | 144.21 |
Density | 0.9 g/mL at 25 °C (lit.) |
Schmelzpunkt | -21.25°C (estimate) |
Boling Point | 220 °C (lit.) |
Flash Point | 232°F |
Waasserléislechkeet | slightly soluble |
Solubility | H2O: slightly soluble |
Vapor Presure | 0.01 hPa (20 °C) |
Ausgesinn | Colorless liquid |
Color | Clear colorless to pale yellow |
Merck | 14,9913 |
BRN | 1750447 |
pKa | 4.6(at 25℃) |
Storage Condition | Store below +30°C. |
Explosive Limit | 1%(V) |
Refractive Index | n20/D 1.425(lit.) |
MDL | MFCD00002672 |
Physical and Chemical Properties | Density: 0.92 Boiling Point: 220°C refractive index: 1.424-1.426 flash point: 111°C water-soluble clear solution |
Benotzt | Used as a pharmaceutical Intermediate |
1. Sidd Dir eng Fabréck oder eng Handelsfirma?
Mir sinn e Gesellschaft, deen d'Industrie an den Handel integréiert, e One-Stop-Service ubitt.OEM kéint akzeptéiert ginn.
2. Gitt Dir Proben? Ass et gratis oder extra?
Gratis Echantillon.D'Prouf Frachtgebühr muss vun Ärer Säit bezuelt ginn.
3. Hutt Dir Certificaten am Zesummenhang mat Qualitéitskontroll?
ISO 9001:2008 Zertifizéierung fir Qualitéit ze garantéieren.
4. Wat soll ech ubidden fir en Devis ze kréien?
Pls informéiert eis iwwer d'Produkttyp déi Dir braucht, d'Bestellquantitéit, d'Adress a spezifesch Ufuerderungen. D'Zitat gëtt fir Är Referenz an der Zäit gemaach.
5. Wéi eng Bezuelmethod léiwer Dir? Wéi eng Konditioune ginn ugeholl?
Akzeptéiert Liwwerung Konditioune: FOB, CFR, CIF, EXW;
Accepted Payment Currency:USD;EUR
Akzeptéiert Bezuelungstyp: T / T, Western Union; Paypal, Trade Assurance.
Sprooch geschwat: Englesch.
Produit Kategorien