valproicacid (VPA) is a broad-spectrum antiepileptic drug in clinical first-line, which has a good effect on various types of epilepsy and concurrent epileptoid convulsions. The metabolism of valproic acid has large individual differences, and its therapeutic window is narrow, and it interacts with a variety of drugs, which often requires therapeutic monitoring. The effective blood concentration range is 50-100 μg/mL. As early as 1882, Professor Beverley Burton of France synthesized valproic acid in his laboratory. Valproic acid is a colorless liquid at room temperature, and since pharmacological studies have shown that this compound has no pharmacological effect, valproic acid has always been a solvent commonly used in the laboratory. If the drug is insoluble to water, valproic acid will be used instead of the solvent to dissolve the drug.
Colorless liquid. Boiling point 221℃, relative density 1.1 (24.5/4℃), refractive index 1.4250, flash point 111℃. Insoluble in water.
The product is salt with sodium hydroxide solution to obtain a broad spectrum anti-epileptic melting drug sodium valproate, also known as anti-epilepsy.
- It can also be used as a modifier to improve the properties of polyesters, plastics and coatings.
Wy hawwe in protte heechweardige fabriken mei djippe gearwurking, dy't jo produkten fan hege kwaliteit en konkurrearjende prizen kinne leverje. En wy kinne ek jouwe koartingen foar bulk oankeapen.En wy gearwurkje mei in protte profesjonele frachtferfier bedriuwen, kinne leverje produkten feilich en soepel oan jo hannen. Levertiid is sawat 3-20 dagen nei befêstiging fan betelling.
Molecular Formula | C8H16O2 |
Molar Mass | 144.21 |
Density | 0.9 g/mL at 25 °C (lit.) |
Smeltpunt | -21.25°C (estimate) |
Boling Point | 220 °C (lit.) |
Flash Point | 232°F |
Wetteroplosberens | slightly soluble |
Solubility | H2O: slightly soluble |
Vapor Presure | 0.01 hPa (20 °C) |
Ferskining | Colorless liquid |
Color | Clear colorless to pale yellow |
Merck | 14,9913 |
BRN | 1750447 |
pKa | 4.6(at 25℃) |
Storage Condition | Store below +30°C. |
Explosive Limit | 1%(V) |
Refractive Index | n20/D 1.425(lit.) |
MDL | MFCD00002672 |
Physical and Chemical Properties | Density: 0.92 Boiling Point: 220°C refractive index: 1.424-1.426 flash point: 111°C water-soluble clear solution |
Brûke | Used as a pharmaceutical Intermediate |
1. Binne jo in fabryk of in hannelsbedriuw?
Wy binne in bedriuw dat yndustry en hannel yntegrearret, en leveret ien-stop service.OEM koe wurde akseptearre.
2. Biede jo samples? Is it fergees of ekstra?
Fergees samples. De frachtfergoeding fan 'e stekproef moat troch jo kant betelle wurde.
3. Hawwe jo sertifikaten yn ferbân mei kwaliteitskontrôle?
ISO 9001: 2008-sertifikaasje om kwaliteit te garandearjen.
4. Wat moat ik leverje om in offerte te krijen?
Pls ynformearje ús oer it produkttype dat jo nedich binne, bestellingskwantiteit, adres en spesifike easken.
5. Hokker soarte fan betelling metoade jo leaver? Hokker soarte betingsten wurde akseptearre?
Akseptearre leveringsbetingsten: FOB, CFR, CIF, EXW;
Accepted Payment Currency:USD;EUR
Akseptearre betellingstype: T / T, Western Union; Paypal, Trade Assurance.
Sprektaal: Ingelsk.
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