valproicacid (VPA) is a broad-spectrum antiepileptic drug in clinical first-line, which has a good effect on various types of epilepsy and concurrent epileptoid convulsions. The metabolism of valproic acid has large individual differences, and its therapeutic window is narrow, and it interacts with a variety of drugs, which often requires therapeutic monitoring. The effective blood concentration range is 50-100 μg/mL. As early as 1882, Professor Beverley Burton of France synthesized valproic acid in his laboratory. Valproic acid is a colorless liquid at room temperature, and since pharmacological studies have shown that this compound has no pharmacological effect, valproic acid has always been a solvent commonly used in the laboratory. If the drug is insoluble to water, valproic acid will be used instead of the solvent to dissolve the drug.
Colorless liquid. Boiling point 221℃, relative density 1.1 (24.5/4℃), refractive index 1.4250, flash point 111℃. Insoluble in water.
The product is salt with sodium hydroxide solution to obtain a broad spectrum anti-epileptic melting drug sodium valproate, also known as anti-epilepsy.
- It can also be used as a modifier to improve the properties of polyesters, plastics and coatings.
Peb muaj ntau lub Hoobkas zoo nrog kev koom tes sib sib zog nqus, uas tuaj yeem muab koj cov khoom zoo thiab cov nqi sib tw. Thiab peb tseem tuaj yeem muab cov luv nqi rau kev yuav khoom ntau.Thiab peb koom tes nrog ntau lub tuam txhab xa khoom xa tuaj, tuaj yeem xa cov khoom lag luam kom nyab xeeb thiab ntseeg nkaws rau koj txhais tes. Lub sij hawm xa tuaj yog li 3-20 hnub tom qab tau txais kev pom zoo ntawm kev them nyiaj.
Molecular Formula | C8H16O2 |
Molar Mass | 144.21 |
Density | 0.9 g/mL at 25 °C (lit.) |
Melting Point | -21.25°C (estimate) |
Boling Point | 220 °C (lit.) |
Flash Point | 232°F |
Dej Solubility | slightly soluble |
Solubility | H2O: slightly soluble |
Vapor Presure | 0.01 hPa (20 °C) |
Qhov tshwm sim | Colorless liquid |
Color | Clear colorless to pale yellow |
Merck | 14,9913 |
BRN | 1750447 |
pKa | 4.6(at 25℃) |
Storage Condition | Store below +30°C. |
Explosive Limit | 1%(V) |
Refractive Index | n20/D 1.425(lit.) |
MDL | MFCD00002672 |
Physical and Chemical Properties | Density: 0.92 Boiling Point: 220°C refractive index: 1.424-1.426 flash point: 111°C water-soluble clear solution |
Siv | Used as a pharmaceutical Intermediate |
1. Koj puas yog lub Hoobkas lossis tuam txhab lag luam?
Peb yog ib qho kev sib koom ua ke kev lag luam thiab kev lag luam, muab kev pabcuam ib-nres.OEM tuaj yeem txais.
2. Koj puas muab cov qauv? Puas yog dawb lossis ntxiv?
Cov qauv dawb.Cov qauv tus nqi thauj khoom yuav tsum tau them los ntawm koj sab.
3. Koj puas muaj daim ntawv pov thawj ntsig txog kev tswj xyuas zoo?
ISO 9001: 2008 ntawv pov thawj los xyuas kom meej qhov zoo.
4. Kuv yuav muab dab tsi kom tau txais cov lus hais?
Pls qhia peb txog cov khoom lag luam uas koj xav tau, xaj kom muaj nuj nqis, chaw nyob thiab cov kev xav tau tshwj xeeb.Cov lus hais yuav ua rau koj siv sijhawm.
5. Hom kev them nqi twg koj nyiam? Cov nqe lus twg raug lees txais?
Txais Cov Lus Cog Tseg: FOB, CFR, CIF, EXW;
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Hom Kev Them Nyiaj: T / T, Western Union; Paypal, Trade Assurance.
Lus Hais: Lus Askiv.
Cov khoom qeb