Nicorandil

High Purity 99% Assay Nicorandil Pharmaceuticals Powder with CAS 65141-46-0

Lebitso la sehlahisoa:
Nicorandil
Kereiti:
Pharmaceutical Grade
Thepa:
phofo e tšoeu
Ho paka:
25kg / moropa
MOQ:
1 ton
Polokelo:Cool Dry Place
Shelf bophelo:lilemo tse 2

TS'ELISO HONA PDF HLAKOLA

Lintlha

Li-tag

Tlhaloso ea Sehlahisoa

Nicorandil is N-(2-hydroxyethyl)-nicotinamide nitrate (ester). It is a white crystalline powder or white needles with a faint, characteristic odour. It is freely soluble in methan ol, ethanol, aceto ne or glacial acetic acid, slightly soluble in chloro form or water, almost insoluble in ether or benzene. Melting point 88.5-93.5 ºC. Acute toxicity LD50 rat (mg/kg): 1200-1300 orally, 800-1000 intravenously.Nicorandil is a nitric oxid e donor and ATP-sensitive potassium channel opener. A study showed that Nicorandil is able to protect against stress-induced cell death in dystrophin-deficient cardiomyocytes and also preserve cardiac function in the mdx mouse heart subjected to ischemia and reperfusion injury.

Melemo

Re na le lifeme tse ngata tsa boleng bo holimo tse nang le tšebelisano e tebileng, tse ka u fang lihlahisoa tsa boleng bo holimo le litheko tsa tlholisano. Hape re ka fana ka litheolelo bakeng sa ho reka ka bongata.'Me re sebelisana le lik'hamphani tse ngata tsa litsebi tse tsamaisang thepa, li ka isa lihlahisoa ka mokhoa o sireletsehileng le ka thelelo matsohong a hau. Nako ea ho fana e ka ba matsatsi a 3-20 ka mor'a hore ho netefatsoe tefo.

Tlhaloso

Items	Standard	Liphetho
APPEARANCE	Off white to white powder	Phofo e tšoeu
IDENTIFICATION	A: IR B: Retention time	E lumellana E lumellana
WATER	≤0.5%	0.06%
HEAVY METALS	≤0.002%	E lumellana
ISOMERS	SFBD1≤0.15%	Undetected
	SFBD2≤0.15%	Undetected
	SFBE≤0.15%	Undetected
RELATED SUBSTANCES	SFBA-1≤0.15%	0.04%
	SFBMA≤0.15%	Undetected
	CHLORO-SFB≤0.15%	0.05%
	DiSFBMA-SFB≤0.15%	0.02%
	Methyl-SFB≤0.15%	Undetected
	Pentafluoro-phenol≤0.15%	Undetected
	Amino-SFB≤0.15%	Undetected
	Any unknown impurity≤0.1%	0.04%
	Total impurity≤1.0%	0.21%
RESIDUE SOLBENTS	Methanol≤3000ppm	Undetected
	Isopropyl alcohol≤5000ppm	19ppm
	Dichloromethane≤600ppm	Undetected
	Tetrahydrofuran≤720ppm	Undetected
	Acetic acid≤5000ppm	Undetected
	Toluene≤890ppm	Undetected
	Chlorobenzene≤360ppm	Undetected
	Methyl tert-butyl ether≤5000ppm	103ppm
ASSAY	≥99.0%	99.8%
RESULT: It complies to prescribed enterprise standard

Tsebo ea sehlahisoa:

Nicorandil is used for the prevention and treatment of chronic stable angina. It is usually used when angina becomes difficult to control by other drugs and is given as an additional treatment.

Ho romella le ho lefa

LBH

1. Na u feme kapa k'hamphani ea khoebo?
Re komnay e kopanyang indasteri le khoebo, ho fana ka ts'ebeletso e le 'ngoe.OEM e ka amoheloa.

2. O fana ka mehlala? Na ke mahala kapa ho feta?
Mehlala ea mahala. Tefiso ea thepa ea sampole e hloka ho lefuoa ka lehlakore la hau.

3. O na le litifikeiti tse amanang le taolo ea boleng?
Setifikeiti sa ISO 9001:2008 ho netefatsa boleng.

4. Ke fane ka eng ho fumana khotheishene?
Pls re tsebise ka mofuta oa sehlahisoa seo u se hlokang, bongata ba odara, aterese le litlhoko tse ikhethileng. Khotheishene e tla etsoa bakeng sa referense ea hau ka nako.

5. U khetha mofuta ofe oa mokhoa oa ho lefa? Ke mantsoe a mofuta ofe a amoheloang?
Melao e Amoheletsoeng ea Thomello: FOB,CFR,CIF,EXW;
Chelete ea Tefo e Amoheletsoeng: USD;
Mofuta oa Tefo o Amoheletsoeng: T/T, Western Union; Paypal, Tiisetso ea Khoebo.
Puo e Builoeng: Senyesemane.

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