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Nicorandil

High Purity 99% Assay Nicorandil Pharmaceuticals Powder with CAS 65141-46-0

 

  • Inoa mea kūʻai:

    Nicorandil

  • Papa:

    Pharmaceutical Grade

  • Nā waiwai:

    pauda keʻokeʻo

  • Hoʻopili:

    25kg / pahu

  • MOQ:

    1 ton

  • Waihona:Wahi Maloo Puanu
  • Ola ola:2 makahiki


Nā kikoʻī

Nā huaʻōlelo

Hōʻike huahana

 

Nicorandil is N-(2-hydroxyethyl)-nicotinamide nitrate (ester). It is a white crystalline powder or white needles with a faint, characteristic odour. It is freely soluble in methan ol, ethanol, aceto ne or glacial acetic acid, slightly soluble in chloro form or water, almost insoluble in ether or benzene. Melting point 88.5-93.5 ºC. Acute toxicity LD50 rat (mg/kg): 1200-1300 orally, 800-1000 intravenously.Nicorandil is a nitric oxid e donor and ATP-sensitive potassium channel opener. A study showed that Nicorandil is able to protect against stress-induced cell death in dystrophin-deficient cardiomyocytes and also preserve cardiac function in the mdx mouse heart subjected to ischemia and reperfusion injury.

 

Nā pono

 

Loaʻa iā mākou nā hale hana kiʻekiʻe me ka pilina hohonu, hiki iā ia ke hāʻawi iā ʻoe i nā huahana kiʻekiʻe a me nā kumukūʻai hoʻokūkū. A hiki iā mākou ke hāʻawi i nā uku no nā kūʻai nui. A ke hui pū nei mākou me nā ʻoihana lawe ukana ʻoihana he nui, hiki ke hāʻawi i nā huahana me ka palekana a me ka maʻalahi i kou mau lima. ʻO ka manawa hoʻouna ma kahi o 3-20 mau lā ma hope o ka hōʻoia ʻana o ka uku.

Hōʻike

 

Items Kūlana Nā hualoaʻa
APPEARANCE Off white to white powder Pauda keʻokeʻo
IDENTIFICATION A: IR
B: Retention time
Hoʻokō
Hoʻokō
WATER ≤0.5% 0.06%
HEAVY METALS ≤0.002% Hoʻokō
ISOMERS SFBD1≤0.15% Undetected
  SFBD2≤0.15% Undetected
  SFBE≤0.15% Undetected
RELATED SUBSTANCES SFBA-1≤0.15% 0.04%
  SFBMA≤0.15% Undetected
  CHLORO-SFB≤0.15% 0.05%
  DiSFBMA-SFB≤0.15% 0.02%
  Methyl-SFB≤0.15% Undetected
  Pentafluoro-phenol≤0.15% Undetected
  Amino-SFB≤0.15% Undetected
  Any unknown impurity≤0.1% 0.04%
  Total impurity≤1.0% 0.21%
RESIDUE SOLBENTS Methanol≤3000ppm Undetected
  Isopropyl alcohol≤5000ppm 19ppm
  Dichloromethane≤600ppm Undetected
  Tetrahydrofuran≤720ppm Undetected
  Acetic acid≤5000ppm Undetected
  Toluene≤890ppm Undetected
  Chlorobenzene≤360ppm Undetected
  Methyl tert-butyl ether≤5000ppm 103ppm
ASSAY ≥99.0% 99.8%
RESULT:  It complies to prescribed enterprise standard

 

ʻIke huahana:

 

Nicorandil is N-(2-hydroxyethyl)-nicotinamide nitrate (ester). It is a white crystalline powder or white needles with a faint, characteristic odour. It is freely soluble in methan ol, ethanol, aceto ne or glacial acetic acid, slightly soluble in chloro form or water, almost insoluble in ether or benzene. Melting point 88.5-93.5 ºC. Acute toxicity LD50 rat (mg/kg): 1200-1300 orally, 800-1000 intravenously.

Nicorandil is used for the prevention and treatment of chronic stable angina. It is usually used when angina becomes difficult to control by other drugs and is given as an additional treatment.

Hoʻouna a me ka uku


 

FAQ

 

1. He hale hana ʻoe a he hui kālepa paha?
He compnay mākou e hoʻohui i ka ʻoihana a me ke kālepa, e hāʻawi ana i ka lawelawe hoʻokahi. Hiki ke ʻae ʻia ʻo OEM.

2. Hāʻawi anei ʻoe i nā laʻana? He manuahi a keu paha?
Free samples.The sample's freight fee Pono e uku ma kou aoao.

3. Loaʻa iā ʻoe nā palapala hōʻoia e pili ana i ka mana maikaʻi?
ISO 9001: 2008 palapala hōʻoia e hōʻoia i ka maikaʻi.

4. He aha kaʻu e hāʻawi ai e kiʻi i kahi ʻōlelo?
E haʻi mai ʻo Pls iā mākou i ke ʻano huahana āu e pono ai, ka nui o ke kauoha, ka helu a me nā koi kikoʻī. E hana ʻia ka ʻōlelo no kāu kuhikuhi i ka manawa.

5. He aha ke ʻano o ka uku uku āu e makemake ai? He aha ke ʻano o nā ʻōlelo i ʻae ʻia?
ʻAe ʻia nā ʻōlelo hoʻouna: FOB, CFR, CIF, EXW;
ʻAe ʻia ke kālā uku:USD;
ʻAno uku i ʻae ʻia: T / T, Western Union; Paypal, Hōʻoia Kūʻai.
ʻŌlelo i ʻōlelo ʻia: English.

 

Inā makemake ʻoe i kā mākou huahana, hiki iā ʻoe ke koho e waiho i kāu ʻike ma aneʻi, a e hoʻopili koke mākou iā ʻoe.


E kākau i kāu leka ma aneʻi a hoʻouna mai iā mākou