remdesivir (GS-5734) is a novel nucleoside analogues antiviral developed by GileadScience Company (GileadScience), an RNA-dependent RNA polymeric Chemicalbook enzyme (RdRp) inhibitor. It can play an antiviral role by inhibiting the synthesis of viral nucleic acid. Redesivir is not currently on the market in the world, phase I and Phase II clinical trials for the indication of anti-Ebola virus (filovirus), phase III trials have not yet started.
GS-441524 is a small molecule, riboside triphosphate competitive inhibitor, that has demonstrated strong antiviral activity against many RNA viruses. It can inhibit the replication of several different types of RNA viruses, such as zoonotic severe acute respiratory syndrome (SARS) coronavirus, Middle East Respiratory syndrome virus, Ebola virus, Lassa fever virus, Junin virus, and respiratory syncytial virus, while having low cytotoxicity in a wide range of cell lines.
Re na le lifeme tse ngata tsa boleng bo holimo tse nang le tšebelisano e tebileng, tse ka u fang lihlahisoa tsa boleng bo holimo le litheko tsa tlholisano. Hape re ka fana ka litheolelo bakeng sa ho reka ka bongata.'Me re sebelisana le lik'hamphani tse ngata tsa litsebi tse tsamaisang thepa, li ka isa lihlahisoa ka mokhoa o sireletsehileng le ka thelelo matsohong a hau. Nako ea ho fana e ka ba matsatsi a 3-20 ka mor'a hore ho netefatsoe tefo.
Molecular Formula | C12H13N5O4 |
Molar Mass | 291.26 |
Density | 1.84±0.1 g/cm3(Predicted) |
Melting Point | > 233° C (dec.) |
Solubility | Dissolved in DMSO |
Ponahalo | Form solid, color Off-white |
Color | Off-white |
pKa | 12.13±0.70(Predicted) |
Storage Condition | -20°C |
Botsitso | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. |
Sebelisa | Use GS-441524 is a small molecule, a competitive inhibitor of nucleoside triphosphate, which shows strong antiviral activity against many RNA viruses. It can inhibit the replication of several different types of RNA viruses, such as severe acute respiratory syndrome (SARS) coronavirus, Middle East respiratory syndrome virus, Ebola virus, Lassa fever virus, Junin virus and respiratory syncytial virus, etc., and has low cytotoxicity in a wide range of cell lines. |
1. Na u feme kapa k'hamphani ea khoebo?
Re komnay e kopanyang indasteri le khoebo, ho fana ka ts'ebeletso e le 'ngoe.OEM e ka amoheloa.
2. O fana ka mehlala? Na ke mahala kapa ho feta?
Mehlala ea mahala. Tefiso ea thepa ea sampole e hloka ho lefuoa ka lehlakore la hau.
3. O na le litifikeiti tse amanang le taolo ea boleng?
Setifikeiti sa ISO 9001:2008 ho netefatsa boleng.
4. Ke fane ka eng ho fumana khotheishene?
Pls re tsebise ka mofuta oa sehlahisoa seo u se hlokang, bongata ba odara, aterese le litlhoko tse ikhethileng. Khotheishene e tla etsoa bakeng sa referense ea hau ka nako.
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