GS-441524 CAS 1191237-69-0

GS-441524 CAS 1191237-69-0

Magaca alaabta:
GS-441524 CAS 1191237-69-0
Darajo:
Darajada daawada
Guryaha:
budo cad
Baakad:
25kg/durbaan
MOQ:
1 g
Kaydinta:Meel qallalan oo qabow
Nolosha shelf:2 sano

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Sharaxaada Alaabta

remdesivir (GS-5734) is a novel nucleoside analogues antiviral developed by GileadScience Company (GileadScience), an RNA-dependent RNA polymeric Chemicalbook enzyme (RdRp) inhibitor. It can play an antiviral role by inhibiting the synthesis of viral nucleic acid. Redesivir is not currently on the market in the world, phase I and Phase II clinical trials for the indication of anti-Ebola virus (filovirus), phase III trials have not yet started.

Codsiga

GS-441524 is a small molecule, riboside triphosphate competitive inhibitor, that has demonstrated strong antiviral activity against many RNA viruses. It can inhibit the replication of several different types of RNA viruses, such as zoonotic severe acute respiratory syndrome (SARS) coronavirus, Middle East Respiratory syndrome virus, Ebola virus, Lassa fever virus, Junin virus, and respiratory syncytial virus, while having low cytotoxicity in a wide range of cell lines.

Faa'iidooyinka

Waxaan leenahay warshado badan oo tayo sare leh oo leh iskaashi qoto dheer, kuwaas oo ku siin kara alaab tayo sare leh iyo qiimo tartan leh. Waxaan sidoo kale ku siin karnaa qiimo-dhimis iibsasho badan. Oo waxaanu la shaqaynaa shirkado badan oo soo gudbiya xamuulka, waxaanu u gaarsiin karnaa alaabta si badbaado leh oo qumman gacmahaaga. Waqtiga bixinta waa qiyaastii 3-20 maalmood kadib xaqiijinta lacag bixinta.

Tilmaamid

Molecular Formula	C12H13N5O4
Molar Mass	291.26
Density	1.84±0.1 g/cm3(Predicted)
Meesha dhalaalaysa	> 233° C (dec.)
Solubility	Dissolved in DMSO
Muuqashada	Form solid, color Off-white
Color	Off-white
pKa	12.13±0.70(Predicted)
Storage Condition	-20°C
Xasilooni	Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Isticmaal	Use GS-441524 is a small molecule, a competitive inhibitor of nucleoside triphosphate, which shows strong antiviral activity against many RNA viruses. It can inhibit the replication of several different types of RNA viruses, such as severe acute respiratory syndrome (SARS) coronavirus, Middle East respiratory syndrome virus, Ebola virus, Lassa fever virus, Junin virus and respiratory syncytial virus, etc., and has low cytotoxicity in a wide range of cell lines.

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1. Ma waxaad tahay warshad ama shirkad ganacsi?
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