GS-441524 CAS 1191237-69-0

GS-441524 CAS 1191237-69-0

igoa ole oloa:
GS-441524 CAS 1191237-69-0
Vasega:
Vasega vailaau
Meatotino:
pa'epa'e pa'epa'e
afifiina:
25kg/papa
MOQ:
1 g
Teuina:Malua Matutu Nofoaga
Ola fa'asa:2 tausaga

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Fa'amatalaga

Fa'ailoga

Fa'amatalaga o oloa

remdesivir (GS-5734) is a novel nucleoside analogues antiviral developed by GileadScience Company (GileadScience), an RNA-dependent RNA polymeric Chemicalbook enzyme (RdRp) inhibitor. It can play an antiviral role by inhibiting the synthesis of viral nucleic acid. Redesivir is not currently on the market in the world, phase I and Phase II clinical trials for the indication of anti-Ebola virus (filovirus), phase III trials have not yet started.

Fa'atatauga

GS-441524 is a small molecule, riboside triphosphate competitive inhibitor, that has demonstrated strong antiviral activity against many RNA viruses. It can inhibit the replication of several different types of RNA viruses, such as zoonotic severe acute respiratory syndrome (SARS) coronavirus, Middle East Respiratory syndrome virus, Ebola virus, Lassa fever virus, Junin virus, and respiratory syncytial virus, while having low cytotoxicity in a wide range of cell lines.

Tulaga lelei

E tele a matou fale gaosi oloa maualuga ma le galulue faʻatasi, lea e mafai ona tuʻuina atu ia te oe oloa maualuga ma tau faʻatauvaʻa. Ma e mafai foi ona matou tuʻuina atu faʻaitiitiga mo faʻatauga tele.Ma matou te galulue faʻatasi ma le tele o kamupani faʻapolofesa felauaiga uta, e mafai ona tuʻuina atu oloa ma le saogalemu ma le sologa lelei i ou lima. Le taimi tu'uina atu e tusa ma le 3-20 aso talu ona fa'amaonia le totogiina.

Fa'amatalaga

Molecular Formula	C12H13N5O4
Molar Mass	291.26
Density	1.84±0.1 g/cm3(Predicted)
Lisi Lisi	> 233° C (dec.)
Solubility	Dissolved in DMSO
Fa'aaliga	Form solid, color Off-white
Color	Off-white
pKa	12.13±0.70(Predicted)
Storage Condition	-20°C
Maumau	Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Fa'aoga	Use GS-441524 is a small molecule, a competitive inhibitor of nucleoside triphosphate, which shows strong antiviral activity against many RNA viruses. It can inhibit the replication of several different types of RNA viruses, such as severe acute respiratory syndrome (SARS) coronavirus, Middle East respiratory syndrome virus, Ebola virus, Lassa fever virus, Junin virus and respiratory syncytial virus, etc., and has low cytotoxicity in a wide range of cell lines.

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