GS-441524 CAS 1191237-69-0

GS-441524 CAS 1191237-69-0

Inoa mea kūʻai:
GS-441524 CAS 1191237-69-0
Papa:
Papa lāʻau lapaʻau
Nā waiwai:
pauda keʻokeʻo
Hoʻopili:
25kg / pahu
MOQ:
1 g
Waihona:Wahi Maloo Puanu
Ola ola:2 makahiki

E HOAKAKA ANO HOOLAHA PDF

Nā kikoʻī

Nā huaʻōlelo

Hōʻike huahana

remdesivir (GS-5734) is a novel nucleoside analogues antiviral developed by GileadScience Company (GileadScience), an RNA-dependent RNA polymeric Chemicalbook enzyme (RdRp) inhibitor. It can play an antiviral role by inhibiting the synthesis of viral nucleic acid. Redesivir is not currently on the market in the world, phase I and Phase II clinical trials for the indication of anti-Ebola virus (filovirus), phase III trials have not yet started.

Palapala noi

GS-441524 is a small molecule, riboside triphosphate competitive inhibitor, that has demonstrated strong antiviral activity against many RNA viruses. It can inhibit the replication of several different types of RNA viruses, such as zoonotic severe acute respiratory syndrome (SARS) coronavirus, Middle East Respiratory syndrome virus, Ebola virus, Lassa fever virus, Junin virus, and respiratory syncytial virus, while having low cytotoxicity in a wide range of cell lines.

Nā pono

Loaʻa iā mākou nā hale hana kiʻekiʻe me ka pilina hohonu, hiki iā ia ke hāʻawi iā ʻoe i nā huahana kiʻekiʻe a me nā kumukūʻai hoʻokūkū. A hiki iā mākou ke hāʻawi i nā uku no nā kūʻai nui. A ke hui pū nei mākou me nā ʻoihana lawe ukana ʻoihana he nui, hiki ke hāʻawi i nā huahana me ka palekana a me ka maʻalahi i kou mau lima. ʻO ka manawa hoʻouna ma kahi o 3-20 mau lā ma hope o ka hōʻoia ʻana o ka uku.

Hōʻike

Molecular Formula	C12H13N5O4
Molar Mass	291.26
Density	1.84±0.1 g/cm3(Predicted)
Lae hehee	> 233° C (dec.)
Solubility	Dissolved in DMSO
Ka nana aku	Form solid, color Off-white
Color	Off-white
pKa	12.13±0.70(Predicted)
Storage Condition	-20°C
Paʻa	Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Hoʻohana	Use GS-441524 is a small molecule, a competitive inhibitor of nucleoside triphosphate, which shows strong antiviral activity against many RNA viruses. It can inhibit the replication of several different types of RNA viruses, such as severe acute respiratory syndrome (SARS) coronavirus, Middle East respiratory syndrome virus, Ebola virus, Lassa fever virus, Junin virus and respiratory syncytial virus, etc., and has low cytotoxicity in a wide range of cell lines.

Hoʻouna a me ka uku

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