Demoxepam CAS 963-39-3

Demoxepam is a major metabolite of Chlordiazepoxide. Demoxepam showed cytotoxic activity against cancer cell lines. Demoxepam has anticonvulsant and antianxiety effects.
Chemical property
White crystal (dichloromethane/hexane). Melting point 239-241℃.

5-chloro-3-phenylbenzoisoxazole was synthesized by cyclic synthesis of p-nitrochlorobenzene and benzyl nitrile in ethanol with the participation of sodium hydroxide, then 2-amino-5-chlorobenzophenone was obtained by reduction and ring-opening with iron powder and hydrochloric acid, and then 2-amino-5-chlorobenzophenone oxime was obtained by hydroxylamine hydrochloride. The latter was combined with chloroacetyl chloride to obtain 6-chloro-2-chloromethyl-4-phenylquinazolin-3-oxide, which was then expanded under the action of sodium hydroxide to obtain the product.
1. Intermediates of Anning and Suning (norazepam).
2. It has anti-convulsive and anti-anxiety effects.

Dufite inganda nyinshi zo mu rwego rwo hejuru hamwe nubufatanye bwimbitse, zishobora kuguha ibicuruzwa byiza kandi nibiciro byapiganwa. Turashobora kandi gutanga kugabanyirizwa kugura byinshi.Kandi turafatanya namasosiyete menshi yohereza ibicuruzwa byumwuga, birashobora gutanga ibicuruzwa neza kandi neza mumaboko yawe. Igihe cyo gutanga ni iminsi 3-20 nyuma yo kwemeza ko wishyuye.

Product Name:	Demoxepam
Synonyms:	Chlordiazepoxide lactam;NSC-46007;NSC-46077;1,3-Dihydro-7-chloro-5-phenyl-2H-1,4-benzodiazepin-2-one 4-oxide;Ro 5-2092;Ro 5-2092 lactam;ro5-2092;ro5-2092lactam
URUBANZA:	963-39-3
MF:	C15H11ClN2O2
MW:	286.71
EINECS:	213-515-2
Product Categories:	Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:	963-39-3.mol

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