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Heparin Sodium

High Purity Supply Heparin Sodium with low price CAS: 9041-08-1

 

  • ଉତ୍ପାଦର ନାମ:

    Heparin Sodium

  • ଗ୍ରେଡ୍:

    Pharmaceutical grade

  • ଗୁଣ:

    ଧଳା ପାଉଡର |

  • ପ୍ୟାକିଂ:

    25kg/bag/drum

  • MOQ:

    1 ton

  • ସଂରକ୍ଷଣ:ଥଣ୍ଡା ଶୁଖିଲା ସ୍ଥାନ |
  • ସେଲଫ୍ ଲାଇଫ୍:2 ବର୍ଷ


ବିବରଣୀ

ଟ୍ୟାଗ୍ସ

ଉତ୍ପାଦ ବର୍ଣ୍ଣନା

 

Heparin sodium, an anticoagulant, is a mucopolysaccharide. It is a sodium salt of glucosamine sulfate extracted from the intestinal mucosa of pigs, cattle and sheep. It is secreted by mast cell in the human body and naturally exists in the blood. Heparin sodium has the function of preventing platelet aggregation and destruction, inhibiting the transformation of fibrinogen into fibrin monomers, inhibiting the formation of thromboplastin and antagonizing the formed thromboplastin, preventing the transformation of prothrombin into thrombin, and antagonizing thrombin.

 

ଉତ୍ପାଦ ପ୍ରଦର୍ଶନ

 

 

ବ Features ଶିଷ୍ଟ୍ୟଗୁଡିକ

 

1. Biochemical studies; used for preventing the conversion of prothrombin into thrombin; has blood anti-thrombosis effect.
2. For the delay and prevention of blood clotting.
3.
Heparin sodium salt is a mucopolysaccharides biochemical medicine extracted from porcine small intestinal mucosa with strong anticoagulant activity. Mclcan found it from the liver tissue of dog in the study of the clotting mechanism. Brinkous et al proved that heparin having anticoagulant activity. After the first application of heparin as an anticoagulant in clinical filed, it has drawn worldwide attention. With a strong anticoagulant effect, heparin is the primary choice for prevention and treatment of deep vein thrombosis and other thrombotic diseases.

 

ଆବେଦନ

 

1. The treatment of various diseases concurrent disseminated intravascular coagulation early.
2. Prevention of arterial and venous thrombosis and pulmonary embolism.
3. Treatment of arterial and venous thrombosis and pulmonary embolism, ischemic stroke, unstable angina
(to alleviate the symptoms, prevention of myocardial infarction), acute myocardial infarction (prevention of
early reinfarction and infarct extension, reduce mortality).
4. The artificial lung, peritoneal dialysis or hemodialysis as anticoagulants.
5. thrombolytic therapy as maintenance therapy.
6. Heparin lithium used for the prevention of blood coagulation and blood bank transfusion of blood and
other body save my save.

 

ସୁବିଧା

 

ଗଭୀର ସହଯୋଗ ସହିତ ଆମର ଅନେକ ଉଚ୍ଚ-ଗୁଣାତ୍ମକ କାରଖାନା ଅଛି, ଯାହା ଆପଣଙ୍କୁ ଉଚ୍ଚମାନର ଉତ୍ପାଦ ଏବଂ ପ୍ରତିଯୋଗିତାମୂଳକ ମୂଲ୍ୟ ପ୍ରଦାନ କରିପାରିବ | ଏବଂ ଆମେ ବହୁଳ କ୍ରୟ ପାଇଁ ରିହାତି ମଧ୍ୟ ଦେଇପାରିବା | ଏବଂ ଆମେ ଅନେକ ପେସାଦାର ମାଲ ପରିବହନ ଫରୱାର୍ଡିଂ କମ୍ପାନୀଗୁଡିକ ସହିତ ସହଯୋଗ କରୁ, ଉତ୍ପାଦଗୁଡିକ ନିରାପଦ ଏବଂ ସୁଗମ ଭାବରେ ଆପଣଙ୍କ ହାତରେ ବିତରଣ କରିପାରିବା | ଦେୟ ନିଶ୍ଚିତ ହେବା ପରେ ବିତରଣ ସମୟ ପ୍ରାୟ 3-20 ଦିନ ଅଟେ |

ନିର୍ଦ୍ଦିଷ୍ଟକରଣ

 

检验项目 ଆଇଟମ୍ |

ମାନକ

检验结果  test result

ଦୃଶ୍ୟ

White or almost white hygroscopic powder

ଅନୁକରଣ କରେ |

Solubility

Freely soluble in water

ଅନୁକରଣ କରେ |

 

Identification A

It delays the clothing of   recalcified citrated sheep plasma.

 

ଅନୁକରଣ କରେ |

Identification B

1H-NMR

ଅନୁକରଣ କରେ |

 

 

 

 

Identification C

 

In the chromatogram of related substance, the principal peak    obtained with test solution is     similar in retention time and

shape to the principal peak in the chromatogram obtained    with reference solution.

 

 

 

 

ଅନୁକରଣ କରେ |

Identification D

It complies with the test for sodium

ଅନୁକରଣ କରେ |

 

 

Appearance of solution

A: The solution is clear.

ଅନୁକରଣ କରେ |

B: The solution is not more intensely coloured than

reference solution Y5.

 

ଅନୁକରଣ କରେ |

PH

5.5~8.0

7.3

Nucleotidic impurities

Absorbance at 260 nm: ≤0.15

0.041

Protein

≤0.5%(Dried substance)

0.06%

 

 

 

 

 

 

Related substances

 

Dermatan Sulfate+Chondroitin  Sulfate: not more than the area of the peak due to dermatan

sulfate and chondroitin sulfate in the chromatogram obtained

with reference solution (e)(2.0%)

 

 

 

 

<0.1%

Any other impurity:

No peaks other than the peak due to dermatan

sulfate+chondroitin sulfate are detected

 

 

ନକାରାତ୍ମକ

Nitrogen

1.5%~2.5%(Dried substance)

2.10%

Sodium

10.5%~13.5%(Dried substance)

11.90%

ଭାରୀ ଧାତୁ |

≤30ppm

ଅନୁକରଣ କରେ |

Loss on drying

≤8.0%

1.00%

Becterial endotoxins

<0.01 IU/IU

ଅନୁକରଣ କରେ |

Protency

 

156 IU/mg

Potency(dried substance)

≥150 IU/mg(Dried substance)

158 IU/mg

Specific rotation

≥+50°

:+55°

 

Molecular weight determinations

Mw: 15,000~ 19,000Da;

M24000~≤20%;              ~

≥1.0

15100

11%

2.3

Residual solvents

Ethanol≤4500ppm

1298ppm

 

 

 

 

 

Microbial contamination

A: TAMC≤10 CFU/g TYMC≤10 CFU/g

B: Specified micro organisms Escherichia coli:

negative

Salmonella:               negative Pseudomonas aeruginosa:

negative

 

 

<10 CFU/g <10 CFU/g

Negative Negative negative

Detection conclusion

Comply with the EP & In-house specification.

 

ଉତ୍ପାଦ ଜ୍ଞାନ :

 

Heparin sodium salt, used as an anticoagulant, is a mucopolysaccharide substance, is the sodium salt form of glucosamine sulfate extracted from the intestinal mucosa of pigs, cattle, and sheep. It is secreted by mast cells to be naturally presented the blood inside the human bodies. Heparin can prevent platelet aggregation and destruction, inhibit the conversion from fibrinogen to fibrin monomers, inhibit the formation of thromboplastin and fight against the pre-formed thromboplastin, and also prevent the conversion of prothrombin to thrombin and counteract the antithrombin.

Heparin sodium can delay or prevent blood clotting both in vivo and in vitro. Its mechanism of action is extremely complex and has an impact on many aspects of the coagulation process. Its function is:

1,to inhibit the formation and action of coagulation activating enzymes, thereby preventing the transformation of prothrombin into thrombin;
2,At high concentrations, it has the effect of inhibiting thrombin and other coagulation factors, hindering the transformation of fibrinogen into fibrin;
3,It can prevent the aggregation and destruction of platelet chemobooks. In addition, the anticoagulant effect of heparin sodium is still related to the negatively charged sulfate ions in its molecules. Positive charged alkaline substances such as protamine or toluidine blue can neutralize its negative charge, thus inhibiting its anticoagulant effect. Due to the activation and release of lipoprotein esterase by heparin in the body, it hydrolyzes the triglycerides and low-density lipoprotein of chyle particles, resulting in a lipid-lowering effect.

 

ପରିବହନ ଏବଂ ଦେୟ

 

 

FAQ

 

1. ଆପଣ ଏକ କାରଖାନା ନା ଏକ ବାଣିଜ୍ୟ କମ୍ପାନୀ?
ଆମେ ଏକ କମ୍ପନେ ଶିଳ୍ପ ଏବଂ ବାଣିଜ୍ୟକୁ ଏକୀକୃତ କରି ଏକ ଷ୍ଟପ୍ ସେବା ପ୍ରଦାନ କରୁଛୁ | OEM ଗ୍ରହଣ କରାଯାଇପାରେ |

2. ଆପଣ ନମୁନା ପ୍ରଦାନ କରନ୍ତି କି? ଏହା ମାଗଣା କି ଅତିରିକ୍ତ?
ମାଗଣା ନମୁନା | ନମୁନାର ମାଲ ପରିବହନ ଫି ଆପଣଙ୍କ ପକ୍ଷରେ ଦେବାକୁ ପଡିବ |

3. ଗୁଣାତ୍ମକ ନିୟନ୍ତ୍ରଣ ସହିତ ଆପଣଙ୍କର କ cert ଣସି ପ୍ରମାଣପତ୍ର ଅଛି କି?
ଗୁଣବତ୍ତା ନିଶ୍ଚିତ କରିବାକୁ ISO 9001: 2008 ପ୍ରମାଣପତ୍ର |

4. ଏକ ଉଦ୍ଧୃତି ପାଇବା ପାଇଁ ମୁଁ କ’ଣ ପ୍ରଦାନ କରିବି?
Pls ଆମକୁ ଆବଶ୍ୟକ କରୁଥିବା ଉତ୍ପାଦ ପ୍ରକାର ବିଷୟରେ ସୂଚନା ଦିଅ, ପରିମାଣ, ଠିକଣା ଏବଂ ନିର୍ଦ୍ଦିଷ୍ଟ ଆବଶ୍ୟକତା ଅର୍ଡର କର | ତୁମର ରେଫରେନ୍ସ ପାଇଁ କୋଟେସନ୍ ଠିକ୍ ସମୟରେ ପ୍ରସ୍ତୁତ ହେବ |

5. ଆପଣ କେଉଁ ପ୍ରକାର ଦେୟ ପଦ୍ଧତି ପସନ୍ଦ କରନ୍ତି? କେଉଁ ପ୍ରକାର ସର୍ତ୍ତ ଗ୍ରହଣ କରାଯାଏ?
ଗ୍ରହଣ କରାଯାଇଥିବା ବିତରଣ ସର୍ତ୍ତାବଳୀ: FOB, CFR, CIF, EXW;
ଗ୍ରହଣ କରାଯାଇଥିବା ଦେୟ ମୁଦ୍ରା: USD;
ଗ୍ରହଣ କରାଯାଇଥିବା ଦେୟ ପ୍ରକାର: ଟି / ଟି, ୱେଷ୍ଟର୍ଣ୍ଣ ୟୁନିଅନ୍; ପେପାଲ୍, ବାଣିଜ୍ୟ ନିଶ୍ଚିତତା |
ଭାଷା ସ୍ପୋକେନ୍: ଇଂରାଜୀ |

 

ଯଦି ତୁମେ ଆମର ଉତ୍ପାଦ ପ୍ରତି ଆଗ୍ରହୀ, ତୁମେ ତୁମର ସୂଚନା ଏଠାରେ ଛାଡିବାକୁ ବାଛି ପାରିବ, ଏବଂ ଆମେ ଖୁବ୍ ଶୀଘ୍ର ଆପଣଙ୍କ ସହିତ ଯୋଗାଯୋଗ କରିବୁ |


ତୁମର ବାର୍ତ୍ତା ଏଠାରେ ଲେଖ ଏବଂ ଆମକୁ ପଠାନ୍ତୁ |