methyl ibogamine-18-carboxylate CAS 467-77-6

methyl ibogamine-18-carboxylate CAS 467-77-6, an iboga type alkaloid, inhibits the wnt signaling pathway by decreasing β-catenin expression[1]. Coronaridine (0-40 μM; 24 hours) is against non-cancer cells with IC50 values >40 μM. It agaisnt wnt-dependent cells with IC50 values of 10.4, 11.6 and 24.4 μM for SW480, HCT116 and DLD1cells, respectively[1].Coronaridine (0-40 μM; 24 hours) inhibits β-catenin expression, but the protein levels of p-β--catenin at Ser33, Ser37, and Thr41 and p-β-catenin at Ser 45 [p-b-catenin (S45)] are unchanged[1].In whole-cell patch clamp recordings,Catharanthine (1-300 μM) are respectively co-applied with GABA at concentrations corresponding to the EC30 value for each receptor subtype. 

Ibogamine-18-carboxylic Acid Methyl Ester (CAS# 467-77-6) is a useful research chemical compound. It is used in the biosynthesis of anti-addiction agent from iboga plant.

A ni ọpọlọpọ awọn ile-iṣelọpọ giga-giga pẹlu ifowosowopo jinlẹ, eyiti o le fun ọ ni awọn ọja to gaju ati awọn idiyele ifigagbaga. Ati pe a tun le fun awọn ẹdinwo fun awọn rira olopobobo.Ati pe a ṣe ifọwọsowọpọ pẹlu ọpọlọpọ awọn ile-iṣẹ gbigbe ẹru ẹru ọjọgbọn, le fi awọn ọja ranṣẹ lailewu ati laisiyonu si ọwọ rẹ. Akoko ifijiṣẹ jẹ nipa awọn ọjọ 3-20 lẹhin ijẹrisi isanwo.

Product Name:	methyl ibogamine-18-carboxylate
Synonyms:	methyl ibogamine-18-carboxylate;coronardine;(-)-Ibogamine-18-carboxylic acid methyl ester;Ibogamine-18-carboxylic acid methyl ester;Coronaridin;NSC 127490;methyl ibogamine
CAS:	467-77-6
MF:	C21H26N2O2
MW:	338.448
EINECS:	207-398-7
Product Categories:
Mol File:	467-77-6.mol

1. Ṣe o jẹ ile-iṣẹ tabi ile-iṣẹ iṣowo kan?
A jẹ ile-iṣẹ iṣọpọ compnay ati iṣowo, ti n pese iṣẹ iduro kan.OEM le gba.

2. Ṣe o pese awọn ayẹwo? Ṣe o jẹ ọfẹ tabi afikun?
Awọn ayẹwo ọfẹ.Ọya ẹru ọkọ ayẹwo naa nilo lati san nipasẹ ẹgbẹ rẹ.

3. Ṣe o ni awọn iwe-ẹri eyikeyi ti o ni ibatan si iṣakoso didara?
ISO 9001: 2008 iwe-ẹri lati rii daju didara.

4. Kini MO yẹ ki n pese lati gba agbasọ ọrọ kan?
Pls sọ fun wa iru ọja ti o nilo, iwọn ibere, adirẹsi ati awọn ibeere pataki.Itọkasi yoo ṣee ṣe fun itọkasi rẹ ni akoko.

5. Iru ọna sisan wo ni o fẹ? Iru awọn ofin wo ni a gba?
Awọn ofin Ifijiṣẹ ti a gba: FOB, CFR, CIF, EXW;
Accepted Payment Currency:USD;EUR
Ti gba Isanwo Isanwo: T/T,Western Union; Paypal, Iṣowo Iṣowo.
Ede Sọ: Gẹẹsi.