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Galantamine Hydrobromide

Galantamine Hydrobromide Nootropics Raw Powder CAS 69353-21-5

 

  • Orukọ ọja:Galantamine Hydrobromide
  • Ipele:

    Pharmaceutical ite

  • Awọn ohun-ini:Iyẹfun funfun
  • Iṣakojọpọ:1kg/bag,25kg/drum
  • MOQ:10 kg
  • Ibi ipamọ:Itura Gbẹ Ibi
  • Igbesi aye ipamọ:ọdun meji 2


Awọn alaye

Awọn afi

Apejuwe ọja

 

Galantamine (Nivalin, Razadyne, Razadyne ER, Reminyl, Lycoremine) is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments, particularly those of vascular origin. It is an alkaloid that is obtained synthetically or from the bulbs and flowers of Galanthus Caucasicus (Caucasian snowdrop, Voronov's snowdrop), Galanthus woronowii (Amaryllidaceae) and related genera like Narcissus (daffodil)), Leucojum(snowflake) and Lycoris including Lycoris radiata (Red Spider Lily).

 

Ifihan ọja

 

 

Awọn ẹya ara ẹrọ

 

1.Galanthamine Hydrobromide is the anti-cholinesterase, weak effect.

2.It has strong effect to the central nervous system through the blood brain barrier.

3.It mainly cures the infantile paralysis sequelae, sweeny and myasthenia gravis pseudoparalytica, etc.

4.It also can be applied to puerilism, posttraumatic apoplexy, polyneuritis and radiculitis.Clinic function: mainly used in myasthenia gravis, poliovirus quiescent stage and sequela.

5.It also in polyneuritis, funiculitis and sensorimotor barrier caused by nervous system disease or traumatism.

6,It's major used in Alzheimer's disease, has the principal function for dement and dysmnesia caused byorganic brain damage.

 

 

Ohun elo

 

  1. anti-oxidation series:

bilberry extract, cranberry extract, grape seed extract, elderberry extract, lutein, zeaxanthin, pine bark extract, rosemary extract, pine bark extract. lemon balm extract.

  1. liver protecting:silybum marianum extract, artichoke extract, antrodia camphorate extract, schisandea extract.
  2. immune system enhancer series:wolfberry extract, echinacea extract, tribulus terrestris extract, resveratrol, 5htp, citrus aurantium extract, nettle extract, red cover extract, reishi extract, rhodiola rosea extract, black cohosh extract, astragalus extract, ginseng extract, cinnamomum cassia extract, schisandra chinensis extract.
  3. heat-clearing and detoxifying series:lemon balm extract, dandelion extract.
  4. weight loss series:white kidney bean extract, garcinia cambogia extract, cassia nomame extract, 5htp.
  5. man and woman healthy:yohimbe bark extract, common cnidium extract, epimedium extract, pygeum africanumextract, saw palmetto extract, soybean extract, pueraria lobata extract, wild yam extract.
  6. mushroom extract:reishi extract, maitake extract, shitake extract, cordceps extract.
  7. anti-cancer:resveratrol, wolfberry extract, flaxseed extract, pomegranate extract, bilberry extract.
  8. anti-depressant:passiflora incarnate extract, st john's wort extract.

 

Awọn anfani

 

A ni ọpọlọpọ awọn ile-iṣelọpọ giga-giga pẹlu ifowosowopo jinlẹ, eyiti o le fun ọ ni awọn ọja to gaju ati awọn idiyele ifigagbaga. Ati pe a tun le fun awọn ẹdinwo fun awọn rira olopobobo.Ati pe a ṣe ifọwọsowọpọ pẹlu ọpọlọpọ awọn ile-iṣẹ gbigbe ẹru ẹru ọjọgbọn, le fi awọn ọja ranṣẹ lailewu ati laisiyonu si ọwọ rẹ. Akoko ifijiṣẹ jẹ nipa awọn ọjọ 3-20 lẹhin ijẹrisi isanwo.

 

 

Sipesifikesonu

 

ITEM

PATAKI

RESULT

METHOD

Ifarahan

White powder, neutral odor, highly hygroscopic

Ni ibamu

Visual

Idanimọ

Standard solution and test solution same spot,RF

Ni ibamu

TLC

Specific Optical

-2.4°~ -2.8°

-2.72°

 

Heavy metals (as PB)

≤10ppm

Ni ibamu

AAS

Sulfate (SO4)

≤0.02%

Ni ibamu

Colorimetry

Chloride (Cl)

≤0.02%

Ni ibamu

Colorimetry

Phosphate Ion (P)

≤5ppm

Ni ibamu

Colorimetry

Residual solvent(ethanol)

≤1.0%

Ni ibamu

HS-GC

pH

4.5~7.0

5.10

 

Related substance

Spot not bigger than standard solution spot

No spot

TLC

Water Content

≤2%

0.26%

KF

Assay (dried basis)

98.0%--102.0%

99.48%

Potentiometric titration

Assay (dried basis)

98.5%--100%

99.2%

HPLC

 

 

 

Imọ ọja:

 

Kini ọja yii?

Galanthamine is natural extracted from lycoris radiate,is a tertiary alkaloid derived from snow drop and closely related species. It acts as a reversible competitive acetylcholinesterase (ACHE) inhibitor, while acts weaker on butyrylcholinesterse(BuChE).it is used in the treatment of disorders of the central nerbous system and may be used as an antidote to nonpolarizing muscle relaxants.Galanthamine hydrobromide is a white to almost white powder;sparingly soluble in water; insoluble chloro.form,ether and alcohol.

 

Ohun elo

Galantamine hydrobromide also called as 11-methyl-3-methoxy-4a, 5, 9, 10, 11, 12-hexahydro-6H-benzene and furans [3a, 3, 2-ef] [2] benzazepine-6-ol hydrobromide, is an alkaloid isolated from Lycoris plants. In the 1960 s, China had first successfully isolated it from domestic Medicago Lycoris and Lycoris radiata, The hydrobromide salt is white crystalline powder and is odorless with bitter taste. It is soluble in water. The absorption coefficient (50 ug in 1 ml of water): at 289nm wavelength, it has an absorption coefficient of 79.6~86.2. It is mainly applied to myasthenia gravis, poliomyelitis sequelae and resting stage as well as being used for the treatment of children with cerebral paralysis, polyneuritis, radiculitis and sensory motor disorders caused by nerve disorders or trauma. It is clinically also used for the treatment of Alzheimer's disease as well as treatment of dementia and memory disorders caused by the organic disease of the brain with significant therapeutic effect.

 

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