Galantamine Hydrobromide

Galantamine (Nivalin, Razadyne, Razadyne ER, Reminyl, Lycoremine) is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments, particularly those of vascular origin. It is an alkaloid that is obtained synthetically or from the bulbs and flowers of Galanthus Caucasicus (Caucasian snowdrop, Voronov's snowdrop), Galanthus woronowii (Amaryllidaceae) and related genera like Narcissus (daffodil)), Leucojum(snowflake) and Lycoris including Lycoris radiata (Red Spider Lily).

1.Galanthamine Hydrobromide is the anti-cholinesterase, weak effect.

2.It has strong effect to the central nervous system through the blood brain barrier.

3.It mainly cures the infantile paralysis sequelae, sweeny and myasthenia gravis pseudoparalytica, etc.

4.It also can be applied to puerilism, posttraumatic apoplexy, polyneuritis and radiculitis.Clinic function: mainly used in myasthenia gravis, poliovirus quiescent stage and sequela.

5.It also in polyneuritis, funiculitis and sensorimotor barrier caused by nervous system disease or traumatism.

6,It's major used in Alzheimer's disease, has the principal function for dement and dysmnesia caused byorganic brain damage.

1. anti-oxidation series:

bilberry extract, cranberry extract, grape seed extract, elderberry extract, lutein, zeaxanthin, pine bark extract, rosemary extract, pine bark extract. lemon balm extract.

2. liver protecting:silybum marianum extract, artichoke extract, antrodia camphorate extract, schisandea extract.
3. immune system enhancer series:wolfberry extract, echinacea extract, tribulus terrestris extract, resveratrol, 5htp, citrus aurantium extract, nettle extract, red cover extract, reishi extract, rhodiola rosea extract, black cohosh extract, astragalus extract, ginseng extract, cinnamomum cassia extract, schisandra chinensis extract.
4. heat-clearing and detoxifying series:lemon balm extract, dandelion extract.
5. weight loss series:white kidney bean extract, garcinia cambogia extract, cassia nomame extract, 5htp.
6. man and woman healthy:yohimbe bark extract, common cnidium extract, epimedium extract, pygeum africanumextract, saw palmetto extract, soybean extract, pueraria lobata extract, wild yam extract.
7. mushroom extract:reishi extract, maitake extract, shitake extract, cordceps extract.
8. anti-cancer:resveratrol, wolfberry extract, flaxseed extract, pomegranate extract, bilberry extract.
9. anti-depressant:passiflora incarnate extract, st john's wort extract.

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Ki sa ki pwodui sa a?

Galanthamine is natural extracted from lycoris radiate,is a tertiary alkaloid derived from snow drop and closely related species. It acts as a reversible competitive acetylcholinesterase (ACHE) inhibitor, while acts weaker on butyrylcholinesterse(BuChE).it is used in the treatment of disorders of the central nerbous system and may be used as an antidote to nonpolarizing muscle relaxants.Galanthamine hydrobromide is a white to almost white powder;sparingly soluble in water; insoluble chloro.form,ether and alcohol.

Aplikasyon

Galantamine hydrobromide also called as 11-methyl-3-methoxy-4a, 5, 9, 10, 11, 12-hexahydro-6H-benzene and furans [3a, 3, 2-ef] [2] benzazepine-6-ol hydrobromide, is an alkaloid isolated from Lycoris plants. In the 1960 s, China had first successfully isolated it from domestic Medicago Lycoris and Lycoris radiata, The hydrobromide salt is white crystalline powder and is odorless with bitter taste. It is soluble in water. The absorption coefficient (50 ug in 1 ml of water): at 289nm wavelength, it has an absorption coefficient of 79.6~86.2. It is mainly applied to myasthenia gravis, poliomyelitis sequelae and resting stage as well as being used for the treatment of children with cerebral paralysis, polyneuritis, radiculitis and sensory motor disorders caused by nerve disorders or trauma. It is clinically also used for the treatment of Alzheimer's disease as well as treatment of dementia and memory disorders caused by the organic disease of the brain with significant therapeutic effect.