Memantine hydrochloride is a raw material. It should be prescribed by experienced doctors in the diagnosis and treatment of Alzheimer's dementia and guided by patients. Treatment can only begin when there are caregivers around the patient who regularly supervise the patient's medication. Dementia should be diagnosed in accordance with current diagnostic criteria and guidelines.
Memantine is a medication used to treat moderate-to-severe Alzheimer's disease. It is less preferred than acetylcholinesterase inhibitors such as donepezil. Treatment should only be continued if beneficial effects are seen. It is taken by mouth.
Memantine was approved for medical use in the United States in 2003. It is available as a generic medication. In 2017, it was the 149th most commonly prescribed medication in the United States, with more than four million prescriptions
Memantine is clinically used for the treatment of moderate to severe senile dementia and parkinsonism syndrome. It is a new type of anti-senile dementia drug and can be used for the treatment of moderate to severe senile dementia.
Memantine is used to treat moderate-to-severe Alzheimer's disease, especially for people who are intolerant of or have a contraindication to AChE (acetylcholinesterase) inhibitors.One guideline recommends memantine or an AChE inhibitor be considered in people in the early-to-mid stage of dementia.
Memantine has been associated with a modest improvement; with small positive effects on cognition, mood, behavior, and the ability to perform daily activities in moderate-to-severe Alzheimer's disease. There does not appear to be any benefit in mild disease.
Memantine when added to donepezil in those with moderate-to-severe dementia resulted in "limited improvements" in a 2017 review. The UK National Institute of Clinical Excellence (NICE) issued guidance in 2018 recommending consideration of the combination of memantine with donepezil in those with moderate-to-severe dementia. Effects in autism are unclear. Recent scientific journal reports are showing guarded promise with severe obsessive compulsive disorder.
У нас є багато високоякісних фабрик із глибокою співпрацею, які можуть надати вам продукцію високої якості та конкурентоспроможні ціни. Ми також можемо надавати знижки на оптові закупівлі. Ми співпрацюємо з багатьма професійними транспортно-експедиторськими компаніями, можемо безпечно та без проблем доставити продукти до ваших рук. Термін доставки становить приблизно 3-20 днів після підтвердження оплати.
Пункт |
Requirements |
Test Results |
appearance |
White or almost white crystalline powder |
White crystalline powder |
Identification |
IR |
Comply |
Related substance |
1-methyladamantane ≤0.3% 1,3,5 -trimethyladamantane ≤0.3% Unknow impuritiy ≤0.1% Total impurity ≤0.5% |
0.13% 0.14% <0.1% <0.4% |
Residue on ignition |
≤0.1% |
0.06% |
Heavy matal |
≤10ppm |
<10ppm |
Loss on drying |
≤0.5% |
0.29% |
аналіз |
98.5-101.0% |
99.13% |
Residual Solvents |
Ethyl Acetat: ≤0.5% Ethanol: ≤0.5% |
0.08% 0.12% |
PH |
4.5-5.5 |
5.3 |
Microbial Limits |
Max 5*102 aerobes and fungl per 1g E. Coli: Negative Salmonella: Negative
|
Pass |
Size of distributed particles |
Pass 100μ m |
Conforms |
Висновок |
Meet the requirements |
Memantine is a medication used to treat moderate-to-severe Alzheimer's disease. It is less preferred than acetylcholinesterase inhibitors such as donepezil. Treatment should only be continued if beneficial effects are seen. It is taken by mouth.
Memantine was approved for medical use in the United States in 2003. It is available as a generic medication. In 2017, it was the 149th most commonly prescribed medication in the United States, with more than four million prescriptions
Memantine HCl is the HCl form of Memantine. Memantine is a well- known neuroprotective drug used for the treatment of Alzheimer's disease. It is believed to be the first neuroprotective drug that has achieve clinical approval by US FDA as well as European.
The development of Alzheimer's disease involves the misfolded mutant proteins such as β-amyloid peptide (Aβ, particularly Aβ1−42). These misfolded mutant protein can increase the NMDA response and further cause severe excitotoxicity.
Memantine suppresses this process through acting as the antagonist of the N-methyl-d- aspartate-sensitive glutamate receptor (NMDARs).
Memantine is also under investigation as a potential treatment for other kind of neurodegenerative disorders such as HIV-associated dementia, neuropathic pain, glaucoma, depression, Huntington's disease, ALS and movement disorders, among other.
1. Ви фабрика чи торгова компанія?
Ми є компанією, що об’єднує промисловість і торгівлю, надаємо комплексне обслуговування. OEM може бути прийнято.
2. Ви надаєте зразки? Це безкоштовно чи додатково?
Безкоштовні зразки. Плата за транспортування зразка повинна бути оплачена вами.
3. Чи є у вас сертифікати щодо контролю якості?
Сертифікація ISO 9001:2008 для забезпечення якості.
4. Що я повинен надати, щоб отримати пропозицію?
Будь ласка, повідомте нам тип продукту, який вам потрібен, кількість замовлення, адресу та конкретні вимоги. Ціна буде зроблена для вашої довідки вчасно.
5. Який спосіб оплати ви віддаєте перевагу? Які умови прийняті?
Прийняті умови доставки: FOB, CFR, CIF, EXW;
Валюта прийнятого платежу: USD;
Прийнятий тип оплати: T/T, Western Union; Paypal, гарантія торгівлі.
Мова спілкування: англійська.
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