Memantine

Hot Sale Professional Pharmaceutical Intermediate Memantine CAS 19982-08-2

 

  • Jméno výrobku:

    Memantine

  • Školní známka:

    Farmaceutická kvalita

  • Vlastnosti:

    bílý prášek

  • Balení:

    25 kg/buben

  • MOQ:

    1 ton

  • Úložný prostor:Chladné suché místo
  • Skladovatelnost:2 roky


Podrobnosti

Tagy

Popis výrobku

 

Memantine hydrochloride is a raw material. It should be prescribed by experienced doctors in the diagnosis and treatment of Alzheimer's dementia and guided by patients. Treatment can only begin when there are caregivers around the patient who regularly supervise the patient's medication. Dementia should be diagnosed in accordance with current diagnostic criteria and guidelines.

Memantine is a medication used to treat moderate-to-severe Alzheimer's disease. It is less preferred than acetylcholinesterase inhibitors such as donepezil. Treatment should only be continued if beneficial effects are seen. It is taken by mouth.
Memantine was approved for medical use in the United States in 2003.
 It is available as a generic medication. In 2017, it was the 149th most commonly prescribed medication in the United States, with more than four million prescriptions

Zobrazení produktu

 

Funkce

 

Memantine is clinically used for the treatment of moderate to severe senile dementia and parkinsonism syndrome. It is a new type of anti-senile dementia drug and can be used for the treatment of moderate to severe senile dementia.

aplikace

 

Memantine is used to treat moderate-to-severe Alzheimer's disease, especially for people who are intolerant of or have a contraindication to AChE (acetylcholinesterase) inhibitors.One guideline recommends memantine or an AChE inhibitor be considered in people in the early-to-mid stage of dementia.

Memantine has been associated with a modest improvement; with small positive effects on cognition, mood, behavior, and the ability to perform daily activities in moderate-to-severe Alzheimer's disease. There does not appear to be any benefit in mild disease.

Memantine when added to donepezil in those with moderate-to-severe dementia resulted in "limited improvements" in a 2017 review. The UK National Institute of Clinical Excellence (NICE) issued guidance in 2018 recommending consideration of the combination of memantine with donepezil in those with moderate-to-severe dementia. Effects in autism are unclear. Recent scientific journal reports are showing guarded promise with severe obsessive compulsive disorder.

 

Výhody

 

Máme mnoho vysoce kvalitních továren s hlubokou spoluprací, které vám mohou poskytnout vysoce kvalitní produkty a konkurenceschopné ceny. A můžeme také poskytnout slevy na hromadné nákupy. A spolupracujeme s mnoha profesionálními spedičními společnostmi, dokážeme doručit produkty bezpečně a hladce do vašich rukou. Dodací lhůta je cca 3-20 dní po potvrzení platby.

Specifikace

 

Položka

Requirements

Test Results

appearance

White or almost white crystalline powder 

White crystalline powder 

Identifikace

IR 

Comply 

Related substance 

1-methyladamantane ≤0.3%

1,3,5 -trimethyladamantane ≤0.3%

Unknow impuritiy     ≤0.1%

Total impurity ≤0.5%

0.13%

0.14%

<0.1%

<0.4%

Zbytek po zapálení 

≤0.1% 

0.06%

Heavy matal 

≤10ppm 

<10ppm 

Ztráta sušením 

≤ 0,5 %

0.29%

Zkouška

98.5-101.0%

99.13%

Residual

Solvents

Ethyl Acetat: ≤0.5%

Ethanol: ≤0.5%

0.08%

0.12%

PH

4.5-5.5 

5.3

Microbial Limits

Max 5*102 aerobes and fungl per 1g 

E. Coli: Negative Salmonella: Negative

 

Pass 

Size of distributed particles 

Pass 100μ m

Vyhovuje

Závěr

Meet the requirements 

 

Znalost produktu:

 

Memantine is a medication used to treat moderate-to-severe Alzheimer's disease. It is less preferred than acetylcholinesterase inhibitors such as donepezil. Treatment should only be continued if beneficial effects are seen. It is taken by mouth.
Memantine was approved for medical use in the United States in 2003.
 It is available as a generic medication. In 2017, it was the 149th most commonly prescribed medication in the United States, with more than four million prescriptions

Memantine HCl is the HCl form of Memantine. Memantine is a well- known neuroprotective drug used for the treatment of Alzheimer's disease. It is believed to be the first neuroprotective drug that has achieve clinical approval by US FDA as well as European.
The development of Alzheimer's disease involves the misfolded mutant proteins such as β-amyloid peptide (Aβ, particularly Aβ1−42). These misfolded mutant protein can increase the NMDA response and further cause severe excitotoxicity.
Memantine suppresses this process through acting as the antagonist of the N-methyl-d- aspartate-sensitive glutamate receptor (NMDARs).
Memantine is also under investigation as a potential treatment for other kind of neurodegenerative disorders such as HIV-associated dementia, neuropathic pain, glaucoma, depression, Huntington's disease, ALS and movement disorders, among other. 

 

Doprava a platba

 

 

 

FAQ

 

1. Jste továrna nebo obchodní společnost?
Jsme společnost integrující průmysl a obchod a poskytujeme jednorázové služby. OEM lze přijmout.

2. Poskytujete vzorky? Je to zdarma nebo navíc?
Vzorky zdarma. Poplatek za dopravu vzorku musí být zaplacen vaší stranou.

3. Máte nějaké certifikáty týkající se kontroly kvality?
Certifikace ISO 9001:2008 pro zajištění kvality.

4. Co bych měl poskytnout, abych získal cenovou nabídku?
Pls, informujte nás o typu produktu, který potřebujete, množství objednávky, adresu a specifické požadavky. Cenová nabídka bude pro vaši referenci včas provedena.

5. Jaký způsob platby preferujete? Jaké podmínky jsou přijímány?
Přijaté dodací podmínky: FOB, CFR, CIF, EXW;
Přijatá měna platby:USD;
Přijímaný typ platby: T/T, Western Union; Paypal, Trade Assurance.
Mluvený jazyk: angličtina.

 

Máte-li zájem o naše produkty, můžete zde nechat své údaje a my se vám brzy ozveme.


Zde napište svou zprávu a pošlete nám ji