Memantine

Hot Sale Professional Pharmaceutical Intermediate Memantine CAS 19982-08-2

 

  • Magaca alaabta:

    Memantine

  • Darajo:

    Darajada daawada

  • Guryaha:

    budo cad

  • Baakad:

    25kg/durbaan

  • MOQ:

    1 ton

  • Kaydinta:Meel qallalan oo qabow
  • Nolosha shelf:2 sano


Faahfaahin

Tags

Sharaxaada Alaabta

 

Memantine hydrochloride is a raw material. It should be prescribed by experienced doctors in the diagnosis and treatment of Alzheimer's dementia and guided by patients. Treatment can only begin when there are caregivers around the patient who regularly supervise the patient's medication. Dementia should be diagnosed in accordance with current diagnostic criteria and guidelines.

Memantine is a medication used to treat moderate-to-severe Alzheimer's disease. It is less preferred than acetylcholinesterase inhibitors such as donepezil. Treatment should only be continued if beneficial effects are seen. It is taken by mouth.
Memantine was approved for medical use in the United States in 2003.
 It is available as a generic medication. In 2017, it was the 149th most commonly prescribed medication in the United States, with more than four million prescriptions

Bandhiga Alaabta

 

Astaamaha

 

Memantine is clinically used for the treatment of moderate to severe senile dementia and parkinsonism syndrome. It is a new type of anti-senile dementia drug and can be used for the treatment of moderate to severe senile dementia.

Codsiga

 

Memantine is used to treat moderate-to-severe Alzheimer's disease, especially for people who are intolerant of or have a contraindication to AChE (acetylcholinesterase) inhibitors.One guideline recommends memantine or an AChE inhibitor be considered in people in the early-to-mid stage of dementia.

Memantine has been associated with a modest improvement; with small positive effects on cognition, mood, behavior, and the ability to perform daily activities in moderate-to-severe Alzheimer's disease. There does not appear to be any benefit in mild disease.

Memantine when added to donepezil in those with moderate-to-severe dementia resulted in "limited improvements" in a 2017 review. The UK National Institute of Clinical Excellence (NICE) issued guidance in 2018 recommending consideration of the combination of memantine with donepezil in those with moderate-to-severe dementia. Effects in autism are unclear. Recent scientific journal reports are showing guarded promise with severe obsessive compulsive disorder.

 

Faa'iidooyinka

 

Waxaan leenahay warshado badan oo tayo sare leh oo leh iskaashi qoto dheer, kuwaas oo ku siin kara alaab tayo sare leh iyo qiimo tartan leh. Waxaan sidoo kale ku siin karnaa qiimo-dhimis iibsasho badan. Oo waxaanu la shaqaynaa shirkado badan oo soo gudbiya xamuulka, waxaanu u gaarsiin karnaa alaabta si badbaado leh oo qumman gacmahaaga. Waqtiga bixinta waa qiyaastii 3-20 maalmood kadib xaqiijinta lacag bixinta.

Tilmaamid

 

Shayga

Requirements

Test Results

appearance

White or almost white crystalline powder 

White crystalline powder 

Aqoonsiga

IR 

Comply 

Related substance 

1-methyladamantane ≤0.3%

1,3,5 -trimethyladamantane ≤0.3%

Unknow impuritiy     ≤0.1%

Total impurity ≤0.5%

0.13%

0.14%

<0.1%

<0.4%

Hadhaaga dabka 

≤0.1% 

0.06%

Heavy matal 

≤10ppm 

<10ppm 

Luminta qalajinta 

≤0.5%

0.29%

Qiimayn

98.5-101.0%

99.13%

Residual

Solvents

Ethyl Acetat: ≤0.5%

Ethanol: ≤0.5%

0.08%

0.12%

PH

4.5-5.5 

5.3

Microbial Limits

Max 5*102 aerobes and fungl per 1g 

E. Coli: Negative Salmonella: Negative

 

Pass 

Size of distributed particles 

Pass 100μ m

waafaqsan

Gabagabo

Meet the requirements 

 

Aqoonta alaabta:

 

Memantine is a medication used to treat moderate-to-severe Alzheimer's disease. It is less preferred than acetylcholinesterase inhibitors such as donepezil. Treatment should only be continued if beneficial effects are seen. It is taken by mouth.
Memantine was approved for medical use in the United States in 2003.
 It is available as a generic medication. In 2017, it was the 149th most commonly prescribed medication in the United States, with more than four million prescriptions

Memantine HCl is the HCl form of Memantine. Memantine is a well- known neuroprotective drug used for the treatment of Alzheimer's disease. It is believed to be the first neuroprotective drug that has achieve clinical approval by US FDA as well as European.
The development of Alzheimer's disease involves the misfolded mutant proteins such as β-amyloid peptide (Aβ, particularly Aβ1−42). These misfolded mutant protein can increase the NMDA response and further cause severe excitotoxicity.
Memantine suppresses this process through acting as the antagonist of the N-methyl-d- aspartate-sensitive glutamate receptor (NMDARs).
Memantine is also under investigation as a potential treatment for other kind of neurodegenerative disorders such as HIV-associated dementia, neuropathic pain, glaucoma, depression, Huntington's disease, ALS and movement disorders, among other. 

 

Raridda iyo bixinta

 

 

 

FAQ

 

1. Ma waxaad tahay warshad ama shirkad ganacsi?
Waxaan nahay shirkad isku-dhafan oo warshado iyo ganacsi ah, oo bixisa adeeg hal-joojin ah. OEM waa la aqbali karaa.

2. Ma bixisaa muunado? Ma bilaash baa mise waa dheeraad?
Muunado bilaash ah. Kharashka xamuulka ee muunada waxa loo baahan yahay in dhinacaaga laga bixiyo.

3. Ma haysaa wax shahaado ah oo la xidhiidha ilaalinta tayada?
ISO 9001: 2008 shahaado si loo hubiyo tayada.

4. Maxaan bixiyaa si aan u helo xigasho?
Pls noo soo sheeg nooca badeecada aad u baahan tahay, dalbo tirada, ciwaanka iyo shuruudaha gaarka ah

5. Habka lacag-bixinta noocee ah ayaad doorbidaysaa? Waa maxay nooca shuruudaha la aqbalo?
Shuruudaha keenista la aqbalay: FOB, CFR, CIF, EXW;
Lacagta Bixinta La Oggolyahay: USD;
Nooca Lacag-bixinta La Aqbalay: T/T,Ururka Galbeedka; Paypal, Hubinta Ganacsiga.
Luuqadaha lagu hadlo: Ingiriis.

 

Haddii aad xiisaynayso alaabtayada, waxaad dooran kartaa inaad macluumaadkaaga kaga tagto halkan, wax yarna waanu kula soo xidhiidhi doonaa.


Halkan ku qor fariintaada oo noo soo dir