Memantine

Hot Sale Professional Pharmaceutical Intermediate Memantine CAS 19982-08-2

 

  • Produk Naam:

    Memantine

  • Graad:

    Farmaseutiese graad

  • Eienskappe:

    Wit poeier

  • Verpakking:

    25 kg/drom

  • MOQ:

    1 ton

  • Berging:Koel Droë Plek
  • Raklewe:2 jaar


Besonderhede

Merkers

Produk Beskrywing

 

Memantine hydrochloride is a raw material. It should be prescribed by experienced doctors in the diagnosis and treatment of Alzheimer's dementia and guided by patients. Treatment can only begin when there are caregivers around the patient who regularly supervise the patient's medication. Dementia should be diagnosed in accordance with current diagnostic criteria and guidelines.

Memantine is a medication used to treat moderate-to-severe Alzheimer's disease. It is less preferred than acetylcholinesterase inhibitors such as donepezil. Treatment should only be continued if beneficial effects are seen. It is taken by mouth.
Memantine was approved for medical use in the United States in 2003.
 It is available as a generic medication. In 2017, it was the 149th most commonly prescribed medication in the United States, with more than four million prescriptions

Produk vertoon

 

Kenmerke

 

Memantine is clinically used for the treatment of moderate to severe senile dementia and parkinsonism syndrome. It is a new type of anti-senile dementia drug and can be used for the treatment of moderate to severe senile dementia.

Toepassing

 

Memantine is used to treat moderate-to-severe Alzheimer's disease, especially for people who are intolerant of or have a contraindication to AChE (acetylcholinesterase) inhibitors.One guideline recommends memantine or an AChE inhibitor be considered in people in the early-to-mid stage of dementia.

Memantine has been associated with a modest improvement; with small positive effects on cognition, mood, behavior, and the ability to perform daily activities in moderate-to-severe Alzheimer's disease. There does not appear to be any benefit in mild disease.

Memantine when added to donepezil in those with moderate-to-severe dementia resulted in "limited improvements" in a 2017 review. The UK National Institute of Clinical Excellence (NICE) issued guidance in 2018 recommending consideration of the combination of memantine with donepezil in those with moderate-to-severe dementia. Effects in autism are unclear. Recent scientific journal reports are showing guarded promise with severe obsessive compulsive disorder.

 

Voordele

 

Ons het baie fabrieke van hoë gehalte met diep samewerking, wat u produkte van hoë gehalte en mededingende pryse kan voorsien. En ons kan ook afslag gee vir grootmaat aankope. En ons werk saam met baie professionele vragversending maatskappye, kan produkte veilig en glad aan jou hande lewer. Afleweringstyd is ongeveer 3-20 dae na bevestiging van betaling.

Spesifikasie

 

Item

Requirements

Test Results

appearance

White or almost white crystalline powder 

White crystalline powder 

Identifikasie

IR 

Comply 

Related substance 

1-methyladamantane ≤0.3%

1,3,5 -trimethyladamantane ≤0.3%

Unknow impuritiy     ≤0.1%

Total impurity ≤0.5%

0.13%

0.14%

<0.1%

<0.4%

Residu by ontsteking 

≤0.1% 

0.06%

Heavy matal 

≤10ppm 

<10ppm 

Verlies by droog 

≤0,5%

0.29%

Toets

98.5-101.0%

99.13%

Residual

Solvents

Ethyl Acetat: ≤0.5%

Ethanol: ≤0.5%

0.08%

0.12%

PH

4.5-5.5 

5.3

Microbial Limits

Max 5*102 aerobes and fungl per 1g 

E. Coli: Negative Salmonella: Negative

 

Pass 

Size of distributed particles 

Pass 100μ m

Konformeer

Afsluiting

Meet the requirements 

 

Produk kennis:

 

Memantine is a medication used to treat moderate-to-severe Alzheimer's disease. It is less preferred than acetylcholinesterase inhibitors such as donepezil. Treatment should only be continued if beneficial effects are seen. It is taken by mouth.
Memantine was approved for medical use in the United States in 2003.
 It is available as a generic medication. In 2017, it was the 149th most commonly prescribed medication in the United States, with more than four million prescriptions

Memantine HCl is the HCl form of Memantine. Memantine is a well- known neuroprotective drug used for the treatment of Alzheimer's disease. It is believed to be the first neuroprotective drug that has achieve clinical approval by US FDA as well as European.
The development of Alzheimer's disease involves the misfolded mutant proteins such as β-amyloid peptide (Aβ, particularly Aβ1−42). These misfolded mutant protein can increase the NMDA response and further cause severe excitotoxicity.
Memantine suppresses this process through acting as the antagonist of the N-methyl-d- aspartate-sensitive glutamate receptor (NMDARs).
Memantine is also under investigation as a potential treatment for other kind of neurodegenerative disorders such as HIV-associated dementia, neuropathic pain, glaucoma, depression, Huntington's disease, ALS and movement disorders, among other. 

 

Versending en betaling

 

 

 

Gereelde vrae

 

1. Is jy 'n fabriek of 'n handelsmaatskappy?
Ons is 'n maatskappy wat industrie en handel integreer, wat eenstopdiens lewer. OEM kan aanvaar word.

2. Verskaf u monsters? Is dit gratis of ekstra?
Gratis monsters. Die monster se vragfooi moet aan jou kant betaal word.

3. Het u enige sertifikate wat verband hou met gehaltebeheer?
ISO 9001:2008-sertifisering om kwaliteit te verseker.

4. Wat moet ek verskaf om 'n kwotasie te kry?
Stel ons asseblief in kennis van die produktipe wat u benodig, bestelhoeveelheid, adres en spesifieke vereistes. Die kwotasie sal betyds vir u verwysing gemaak word.

5. Watter soort betaalmetode verkies jy? Watter soort terme word aanvaar?
Aanvaarde afleweringsbepalings: FOB, CFR, CIF, EXW;
Aanvaarde betaling Geldeenheid: USD;
Aanvaarde tipe betaling: T/T, Western Union; Paypal, Handelsversekering.
Gesproke taal: Engels.

 

As jy belangstel in ons produkte, kan jy kies om jou inligting hier te los, en ons sal binnekort met jou in verbinding tree.


Skryf jou boodskap hier en stuur dit vir ons