Aminophylline is a compound of the bronchodilator theophylline with ethy-lenediamine in 2:1 ratio. The ethy-lenediamine improves solubility, and the aminophylline is usually found as a dihydrate.Aminophylline is a compound salt of theophylline and ethylenediamin. Its pharmacological action mainly comes from theophylline,and ethylenediamin enhances its water solubility. This product has direct relaxation effect on respiratory tract smooth muscle, and its mechanism of action is relatively complex.Aminophylline is a compound of the bronchodilator theophylline with ethylenediamin in 2:1 ratio.Aminophylline is less potent and shorter-acting than theophylline. Its most common use is in the treatment of airway obstruction from asthma or COPD.
Aminophylline is a compound of the bronchodilator theophylline with ethylenediamin in 2:1 ratio.Aminophylline is less potent and shorter-acting than theophylline. Its most common use is in the treatment of airway obstruction from asthma or COPD.
Aminophylline can be used as dicuretic and the medicine helping to relax the smooth muscle .The aminophylline can relax the bronchus and the smooth muscle of the blood vessel,inhibit the kidney tubules to reabsorb the sodium and the water and enhance the extraction of heart oedema and so on .It is usually used as mono-medicine.It is mainly used in medicine field.
1. Relax smooth muscle: aminophylline can act on smooth muscle cells, increase the concentration of cyclic adenylate in cells by inhibiting phosphodiesterase, thus relaxing respiratory smooth muscle and dilating bronchus. This relaxing effect can improve airway spasm and increase airway patency, allowing patients to breathe more smoothly.
3. Cardiotropic effect: aminophylline has a mild cardiotropic effect, that is, it can enhance cardiac contractility and cardiac output. This effect can improve oxygen supply and metabolism of tissues and improve cardiorespiratory function in patients with respiratory diseases.
4. Diuretic effect: aminophylline can promote the kidney to urinate and increase urine volume. This diuretic effect helps to remove excess fluid from the body, reducing edema and the burden on the patient's heart.
Re na le lifeme tse ngata tsa boleng bo holimo tse nang le tšebelisano e tebileng, tse ka u fang lihlahisoa tsa boleng bo holimo le litheko tsa tlholisano. Hape re ka fana ka litheolelo bakeng sa ho reka ka bongata.'Me re sebelisana le lik'hamphani tse ngata tsa litsebi tse tsamaisang thepa, li ka isa lihlahisoa ka mokhoa o sireletsehileng le ka thelelo matsohong a hau. Nako ea ho fana e ka ba matsatsi a 3-20 ka mor'a hore ho netefatsoe tefo.
Ntho | Tlhaloso | Liphetho |
Ponahalo | white to yellowish powder | E lumellana |
Assay (theophylline) | 84.0-87.4% | 86.7% |
Assay(Ethylene diamine) | 13.0-15.0% | 13.3% |
Water | ≤0.75% | 0.40% |
Related substances | ≤0.50% | 0.50% |
Sulphated ash | ≤0.1% | 0.05% |
Heavy Metals | ≤20ppm | Confirms |
E.Coli | E mpe | E lumellana |
S.Arueus | E mpe | E lumellana |
Salmonella | E mpe | E lumellana |
Aminophylline is a compound having a ratio of bronchodilator, theophylline to ethy-lenediamine, of 2:1. Aminophylline is less potent and has a shorter effect than theophylline. Its most common use is to treat airway obstruction in asthma or COPD.
Application Area
1. Aminophylline can be used as dicuretic and the medicine helping to relax the smooth muscle .
2. The aminophylline can relax the bronchus and the smooth muscle of the blood vessel,inhibit the kidney
tubules to reabsorb the sodium and the water and enhance the extraction of heart oedema and so on .
3. Aminophylline is usually used as mono-medicine.It is mainly used in medicine field.
1. Na u feme kapa k'hamphani ea khoebo?
Re komnay e kopanyang indasteri le khoebo, ho fana ka ts'ebeletso e le 'ngoe.OEM e ka amoheloa.
2. O fana ka mehlala? Na ke mahala kapa ho feta?
Mehlala ea mahala. Tefiso ea thepa ea sampole e hloka ho lefuoa ka lehlakore la hau.
3. O na le litifikeiti tse amanang le taolo ea boleng?
Setifikeiti sa ISO 9001:2008 ho netefatsa boleng.
4. Ke fane ka eng ho fumana khotheishene?
Pls re tsebise ka mofuta oa sehlahisoa seo u se hlokang, bongata ba odara, aterese le litlhoko tse ikhethileng. Khotheishene e tla etsoa bakeng sa referense ea hau ka nako.
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