Aminophylline

Aminophylline is a compound of the bronchodilator theophylline with ethy-lenediamine in 2:1 ratio. The ethy-lenediamine improves solubility, and the aminophylline is usually found as a dihydrate.Aminophylline is a compound salt of theophylline and ethylenediamin. Its pharmacological action mainly comes from theophylline,and ethylenediamin enhances its water solubility. This product has direct relaxation effect on respiratory tract smooth muscle, and its mechanism of action is relatively complex.Aminophylline is a compound of the bronchodilator theophylline with ethylenediamin in 2:1 ratio.Aminophylline is less potent and shorter-acting than theophylline. Its most common use is in the treatment of airway obstruction from asthma or COPD.

Aminophylline is a compound of the bronchodilator theophylline with ethylenediamin in 2:1 ratio.Aminophylline is less potent and shorter-acting than theophylline. Its most common use is in the treatment of airway obstruction from asthma or COPD.
Aminophylline can be used as dicuretic and the medicine helping to relax the smooth muscle .The aminophylline can relax the bronchus and the smooth muscle of the blood vessel,inhibit the kidney tubules to reabsorb the sodium and the water and enhance the extraction of heart oedema and so on .It is usually used as mono-medicine.It is mainly used in medicine field.

1. Relax smooth muscle: aminophylline can act on smooth muscle cells, increase the concentration of cyclic adenylate in cells by inhibiting phosphodiesterase, thus relaxing respiratory smooth muscle and dilating bronchus. This relaxing effect can improve airway spasm and increase airway patency, allowing patients to breathe more smoothly.

3. Cardiotropic effect: aminophylline has a mild cardiotropic effect, that is, it can enhance cardiac contractility and cardiac output. This effect can improve oxygen supply and metabolism of tissues and improve cardiorespiratory function in patients with respiratory diseases.

4. Diuretic effect: aminophylline can promote the kidney to urinate and increase urine volume. This diuretic effect helps to remove excess fluid from the body, reducing edema and the burden on the patient's heart.

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Aminophylline is a compound having a ratio of bronchodilator, theophylline to ethy-lenediamine, of 2:1. Aminophylline is less potent and has a shorter effect than theophylline. Its most common use is to treat airway obstruction in asthma or COPD.

Application Area

1. Aminophylline can be used as dicuretic and the medicine helping to relax the smooth muscle .

2. The aminophylline can relax the bronchus and the smooth muscle of the blood vessel,inhibit the kidney

tubules to reabsorb the sodium and the water and enhance the extraction of heart oedema and so on .

3. Aminophylline is usually used as mono-medicine.It is mainly used in medicine field.

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