Isotretinoic Acid

lsoretinoic acid belongs to the first generation of vitamin A acids. It is a stereoisomer of all trans vitamin A acid. Oral administration has an anti oil effect and has a special effect on severe acne. It has a strong and rapid function of inhibiting the proliferation and differentiation process of skin gland cells. Clinically used for severe acne, cystic acne, and aggregated acne that are ineffective in the treatment of other drugs.Isoretinoic acid is a type of retinol derivative used in acne treatment products, with improved bioavailability and percutaneous absorption. The appearance is yellow orange crystalline powder. Currently, research is being conducted on the combination of photoaging skin treatment.

1. It can reduce sebaceous gland and inhibit the activity of sebaceous gland, reducing the effect of secretion of the sebaceous glands, thus inhibiting the growth of Propionibacterium which relies on lipid environment.

2. It has an anti-keratosis effect, can inhibit the excess proliferation of epidermal and promote its differentiation. It also reduces the keratosis of hair follicles and the catheter of sebaceous glands.

3. It can also affect the function of lymphocytes and monocytes, and inhibit the chemotaxis of neutrophil, and thus having anti-inflammatory activity.

4. It can exert its therapeutic effect by selectively binding Vitamin A acid nuclear receptors. It can inhibit the proliferation of acne rod bacilli. Moreover it has effects of immunity stimulation at low doses, but has immunity suppression effect at high doses.

5. It can inhibit the biogenesis of collagenase and gelatinase in the skin, and can also inhibit the activity of ornithine decarboxylase. Owing to the major role of ornithine decarboxylase in inducing skin mutations, so Isoretinoic can also suppress tumorigenesis.

6. When subjects to topical administration, it has a similar mechanism of action as vitamin A acid which induces the proliferation of epidermal cell, promotes the differentiation of epidermal cell granular layer into the stratum corneum. It can also regulate the horny plug occurring during some abnormal cornification processes of Hair follicle sebaceous epithelium, and thus playing a therapeutic role.

Vi har mange højkvalitetsfabrikker med dybt samarbejde, som kan give dig produkter af høj kvalitet og konkurrencedygtige priser. Og vi kan også give rabat ved bulkkøb. Og vi samarbejder med mange professionelle speditionsfirmaer, kan levere produkter sikkert og problemfrit til dine hænder. Leveringstiden er omkring 3-20 dage efter bekræftelse af betaling.

1. Er du en fabrik eller en handelsvirksomhed?
Vi er en virksomhed, der integrerer industri og handel, og leverer one-stop service.OEM kunne accepteres.

2. Giver du prøver? Er det gratis eller ekstra?
Gratis prøver. Prøvens fragtgebyr skal betales ved din side.

3. Har du nogen certifikater relateret til kvalitetskontrol?
ISO 9001:2008 certificering for at sikre kvalitet.

4. Hvad skal jeg give for at få et tilbud?
Pls informer os om den produkttype, du har brug for, ordremængde, adresse og specifikke krav. Tilbuddet vil blive lavet til din reference i tide.

5. Hvilken slags betalingsmetode foretrækker du? Hvilken slags vilkår accepteres?
Accepterede leveringsbetingelser: FOB, CFR, CIF, EXW;
Accepted Payment Currency:USD;EUR
Accepteret betalingstype: T/T, Western Union; Paypal, Trade Assurance.
Talt sprog: engelsk.