24α-methyl Cholesterol is a phytosterol found in vegetables, fruits, nuts, and seeds that competitively inhibits the absorption of intestinal cholesterol and decreases the transcription of genes important for cholesterol metabolism. The cholesterol lowering effects of phytosterols, such as 24α-methyl cholesterol, have been reported to be beneficial for lowering the incidence of atherosclerotic plaques. 24α-methyl Cholesterol can also act as an agonist at liver X receptors (LXR) and, through activation of LXR signaling, has been shown to suppress the proliferation of prostate and breast cancer cells.
A phytosterol, which may inhibit the intestinal absorption of cholesterol.
Campesterol may be used as a plant sterol to test its effect on the transcriptional activation of liver X receptor α (LXRA) in breast cancer cells. It may also be used as a sterol standard for calibration curve generation in liquid chromatography multiple reaction monitoring (LC-MRM) analysis.
A ni ọpọlọpọ awọn ile-iṣelọpọ giga-giga pẹlu ifowosowopo jinlẹ, eyiti o le fun ọ ni awọn ọja to gaju ati awọn idiyele ifigagbaga. Ati pe a tun le fun awọn ẹdinwo fun awọn rira olopobobo.Ati pe a ṣe ifọwọsowọpọ pẹlu ọpọlọpọ awọn ile-iṣẹ gbigbe ẹru ẹru ọjọgbọn, le fi awọn ọja ranṣẹ lailewu ati laisiyonu si ọwọ rẹ. Akoko ifijiṣẹ jẹ nipa awọn ọjọ 3-20 lẹhin ijẹrisi isanwo.
Product Name: | CAMPESTEROL |
Synonyms: | (24R)-5-Ergosten-3beta-ol;(24R)-Methylcholest-5-en-3beta-ol;24alpha-Methylcholesterol;Campesterin;DELTA5-24-Isoergosten-3beta-ol;Ergost-5-en-3beta-ol, (24R)-;Ergost-5-en-3-ol;Ergost-5-en-3-ol, (3beta,24R)- |
CAS: | 474-62-4 |
MF: | C28H48O |
MW: | 400.69 |
EINECS: | 207-484-4 |
Product Categories: | pharmaceutical intermediate; |
Mol File: | 474-62-4.mol |
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CAMPESTEROL Chemical Properties |
Ojuami yo | 156-160 °C |
alpha | D23 -33° (22.5 mg in 5 ml chloroform) |
Oju omi farabale | 463.29°C (rough estimate) |
iwuwo | 0.98±0.1 g/cm3 (20 ºC 760 Torr) |
refractive atọka | 1.5100 (estimate) |
iwọn otutu ipamọ. | -20°C |
solubility | Chloroform (Sparingly), Methanol (Slightly, Sonicated) |
pka | 15.03±0.70(Predicted) |
fọọmu | crystalline |
awọ | white |
Merck | 13,1736 |
BRN | 3216975 |
InChIKey | SGNBVLSWZMBQTH-ZRUUVFCLSA-N |
LogP | 9.972 (est) |
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