24α-methyl Cholesterol is a phytosterol found in vegetables, fruits, nuts, and seeds that competitively inhibits the absorption of intestinal cholesterol and decreases the transcription of genes important for cholesterol metabolism. The cholesterol lowering effects of phytosterols, such as 24α-methyl cholesterol, have been reported to be beneficial for lowering the incidence of atherosclerotic plaques. 24α-methyl Cholesterol can also act as an agonist at liver X receptors (LXR) and, through activation of LXR signaling, has been shown to suppress the proliferation of prostate and breast cancer cells.
A phytosterol, which may inhibit the intestinal absorption of cholesterol.
Campesterol may be used as a plant sterol to test its effect on the transcriptional activation of liver X receptor α (LXRA) in breast cancer cells. It may also be used as a sterol standard for calibration curve generation in liquid chromatography multiple reaction monitoring (LC-MRM) analysis.
Waxaan leenahay warshado badan oo tayo sare leh oo leh iskaashi qoto dheer, kuwaas oo ku siin kara alaab tayo sare leh iyo qiimo tartan leh. Waxaan sidoo kale ku siin karnaa qiimo-dhimis iibsasho badan. Oo waxaanu la shaqaynaa shirkado badan oo soo gudbiya xamuulka, waxaanu u gaarsiin karnaa alaabta si badbaado leh oo qumman gacmahaaga. Waqtiga bixinta waa qiyaastii 3-20 maalmood kadib xaqiijinta lacag bixinta.
Product Name: | CAMPESTEROL |
Synonyms: | (24R)-5-Ergosten-3beta-ol;(24R)-Methylcholest-5-en-3beta-ol;24alpha-Methylcholesterol;Campesterin;DELTA5-24-Isoergosten-3beta-ol;Ergost-5-en-3beta-ol, (24R)-;Ergost-5-en-3-ol;Ergost-5-en-3-ol, (3beta,24R)- |
CAS: | 474-62-4 |
MF: | C28H48O |
MW: | 400.69 |
EINECS: | 207-484-4 |
Product Categories: | pharmaceutical intermediate; |
Mol File: | 474-62-4.mol |
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CAMPESTEROL Chemical Properties |
barta dhalaalaysa | 156-160 °C |
alpha | D23 -33° (22.5 mg in 5 ml chloroform) |
Barta karkarinta | 463.29°C (rough estimate) |
cufnaanta | 0.98±0.1 g/cm3 (20 ºC 760 Torr) |
index refractive | 1.5100 (estimate) |
heerkulka kaydinta. | -20°C |
milmay | Chloroform (Sparingly), Methanol (Slightly, Sonicated) |
pka | 15.03±0.70(Predicted) |
qaab | crystalline |
midab | white |
Merck | 13,1736 |
BRN | 3216975 |
InChIKey | SGNBVLSWZMBQTH-ZRUUVFCLSA-N |
LogP | 9.972 (est) |
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