24α-methyl Cholesterol is a phytosterol found in vegetables, fruits, nuts, and seeds that competitively inhibits the absorption of intestinal cholesterol and decreases the transcription of genes important for cholesterol metabolism. The cholesterol lowering effects of phytosterols, such as 24α-methyl cholesterol, have been reported to be beneficial for lowering the incidence of atherosclerotic plaques. 24α-methyl Cholesterol can also act as an agonist at liver X receptors (LXR) and, through activation of LXR signaling, has been shown to suppress the proliferation of prostate and breast cancer cells.
A phytosterol, which may inhibit the intestinal absorption of cholesterol.
Campesterol may be used as a plant sterol to test its effect on the transcriptional activation of liver X receptor α (LXRA) in breast cancer cells. It may also be used as a sterol standard for calibration curve generation in liquid chromatography multiple reaction monitoring (LC-MRM) analysis.
Loaʻa iā mākou nā hale hana kiʻekiʻe me ka pilina hohonu, hiki iā ia ke hāʻawi iā ʻoe i nā huahana kiʻekiʻe a me nā kumukūʻai hoʻokūkū. A hiki iā mākou ke hāʻawi i nā uku no nā kūʻai nui. A ke hui pū nei mākou me nā ʻoihana lawe ukana ʻoihana he nui, hiki ke hāʻawi i nā huahana me ka palekana a me ka maʻalahi i kou mau lima. ʻO ka manawa hoʻouna ma kahi o 3-20 mau lā ma hope o ka hōʻoia ʻana o ka uku.
Product Name: | CAMPESTEROL |
Synonyms: | (24R)-5-Ergosten-3beta-ol;(24R)-Methylcholest-5-en-3beta-ol;24alpha-Methylcholesterol;Campesterin;DELTA5-24-Isoergosten-3beta-ol;Ergost-5-en-3beta-ol, (24R)-;Ergost-5-en-3-ol;Ergost-5-en-3-ol, (3beta,24R)- |
CAS: | 474-62-4 |
MF: | C28H48O |
MW: | 400.69 |
EINECS: | 207-484-4 |
Product Categories: | pharmaceutical intermediate; |
Mol File: | 474-62-4.mol |
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CAMPESTEROL Chemical Properties |
Lae hehee | 156-160 °C |
alpha | D23 -33° (22.5 mg in 5 ml chloroform) |
Lae paila | 463.29°C (rough estimate) |
mānoanoa | 0.98±0.1 g/cm3 (20 ºC 760 Torr) |
hōʻike hoʻopaʻa ʻana | 1.5100 (estimate) |
ka mahana mālama. | -20°C |
hikiwawe | Chloroform (Sparingly), Methanol (Slightly, Sonicated) |
pka | 15.03±0.70(Predicted) |
ʻano | crystalline |
kala kala | white |
Merck | 13,1736 |
BRN | 3216975 |
InChIKey | SGNBVLSWZMBQTH-ZRUUVFCLSA-N |
LogP | 9.972 (est) |
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