Artesunate is used primarily as treatment for malaria; it has also been shown to be >90% efficacious at reducing egg production in Schistosoma haematobium infection.According to WHO intravenous AS is the drug of choice for severe malaria both in children and adults where there is low transmission.In regions where transmission is high, randomized trials among Asian adults and African children strongly advocates the use of artesunate over quinine as the treatment of choice for falciparum malaria.
A ni ọpọlọpọ awọn ile-iṣelọpọ giga-giga pẹlu ifowosowopo jinlẹ, eyiti o le fun ọ ni awọn ọja to gaju ati awọn idiyele ifigagbaga. Ati pe a tun le fun awọn ẹdinwo fun awọn rira olopobobo.Ati pe a ṣe ifọwọsowọpọ pẹlu ọpọlọpọ awọn ile-iṣẹ gbigbe ẹru ẹru ọjọgbọn, le fi awọn ọja ranṣẹ lailewu ati laisiyonu si ọwọ rẹ. Akoko ifijiṣẹ jẹ nipa awọn ọjọ 3-20 lẹhin ijẹrisi isanwo.
Items
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Requirements
|
Esi
|
Appearance:
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White crystals or a white, crystalline powder
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White crystals or a white, crystalline powder.
|
Ojuami yo
|
132°C~135°C
|
133°C
|
Optical rotation
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+10°~+14°
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+13.5°
|
Idanimọ
|
|
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(1) Color Reaction
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Should be positive
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positive
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(2) Color Reaction
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Should be positive
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positive
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(3) TLC
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The principal spot obtained with test solution corresponds in position, appearance, and intensity with that obtained from
reference solution. |
Ni ibamu
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(4) IR
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The infrared absorption spectrum is concordant with the spectrum obtained from Artesunate RS or with the reference spectrum of
artesunate. |
Ni ibamu
|
Idanwo
|
|
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(1) Acidity
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3.5~5.0
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4.5
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(2)Solution transparency and color
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Meet the requirements
|
Ni ibamu
|
(3) Chlorides
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Meet the requirements
|
Ni ibamu
|
(4)related substance
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Just the principal spot can be shown compared with reference, and no other impurity spots are exhibited.
|
Ni ibamu
|
(5) Moisture content
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≤0.5%
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0.003
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(6) Residual on Ignition
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≤ 0.1%
|
0.0006
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(7) Heavy metal
|
Meet the requirements
|
Ni ibamu
|
Assay (on dry basis)
|
98.0% ~102.0%(HPLC)
|
0.9957
|
Ipari
|
The product conforms with CP2010
|
|
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