Berberine Hydrochloride

Berberine hydrochloride, is an organic compound, chemical formula C20H18ClNO4, yellow crystalline powder, soluble in boiling water, slightly soluble in cold water, almost insoluble in cold alcohol, chloroform and ether, mainly used as antibacterial drugs, on dysentery bacillus, Escherichia coli, pneumococcus aureus, streptococcus, typhoid bacillus and amoeba have inhibitory effects. Clinical mainly used for intestinal infection and bacillary dysentery, also found that this product has anti-arrhythmia effect.

Appearance: yellow crystalline powder.

Solubility: easily soluble in boiling water, slightly soluble in cold water, almost insoluble in cold ethanol, chloroform and ether.

Berberine hydrochloride can effectively inhibit the proliferation of various cancer cells, promote apoptosis, and affect MAPK and Wnt/_beta_-catenin pathways.

Мо бисёр заводҳои баландсифат дорем, ки ҳамкориҳои амиқ доранд, ки метавонанд ба шумо маҳсулоти баландсифат ва нархҳои рақобатпазирро пешниҳод кунанд. Ва мо инчунин метавонем барои хариди яклухт тахфиф диҳем. Ва мо бо бисёре аз ширкатҳои экспедитории касбӣ ҳамкорӣ карда, метавонем маҳсулотро ба дасти шумо бехатар ва осонтар расонем. Вақти таҳвил тақрибан 3-20 рӯз пас аз тасдиқи пардохт аст.

pharmacodynamics
The antibacterial spectrum is wide, and it has antibacterial effect on many kinds of gram-positive and gram-negative bacteria in vitro, including hemolytic streptococcus, Staphylococcus aureus and Vibrio cholerae. Meningococcus, Shigella dysentery, typhoid bacillus, diphtheria bacillus have strong inhibitory effect, low concentration of bacteriostasis, high concentration of bactericidal. It also has certain inhibitory effect on influenza virus, amoeba, leptospira and some skin fungi. In vitro experiments show that berberine can enhance the phagocytosis of leukocyte and hepatic reticuloendothelial system. Dysentery bacillus, hemolytic streptococcus, staphylococcus aureus and so on are easy to develop resistance to this product. There is no cross-resistance between this product and penicillin, streptomycin, etc.

pharmacokinetics
Poor oral absorption. After injection, the drug quickly enters the organs and tissues, and the blood concentration is maintained for a short time. The blood concentration after intramuscular injection was lower than the minimum inhibitory concentration. Drugs are widely distributed, mainly in the heart, bone, lung and liver. The retention time in the tissue is short, only a trace amount remains after 24 hours, most of the drugs are metabolized and cleared in the body, and the discharge in its original form within 48 hours only accounts for less than 5% of the dose.

According to recent reports, it is believed that this product can reduce the number of pili on the surface of the body, so that the bacteria can not attach to the human cells, and play a therapeutic role. This product also has an effect on Helicobacter, and can relieve gastritis, gastric and duodenal ulcer.

1. Оё шумо корхона ё ширкати тиҷоратӣ ҳастед?
Мо як ширкате ҳастем, ки саноат ва савдоро муттаҳид карда, хидмати ягонаро пешниҳод мекунем. OEM метавонад қабул карда шавад.

2. Оё шумо намунаҳо пешниҳод мекунед? Оё он ройгон ё иловагӣ?
Намунаҳои ройгон. Пардохти боркашонии намуна бояд аз ҷониби шумо пардохт карда шавад.

3. Оё шумо ягон сертификати марбут ба назорати сифат доред?
Сертификати ISO 9001: 2008 барои таъмини сифат.

4. Барои гирифтани нархнома чиро бояд пешниҳод кунам?
Лутфан ба мо дар бораи намуди маҳсулоте, ки ба шумо лозим аст, миқдори фармоиш, суроға ва талаботи мушаххасро ба мо хабар диҳед. Иқтибос барои истинод ба шумо сари вақт дода мешавад.

5. Кадом намуди пардохти шумо бартарӣ доред? Кадом шартҳо қабул карда мешаванд?
Шартҳои қабули интиқол: FOB, CFR, CIF, EXW;
Асъори пардохти қабулшуда: доллари ИМА;
Намуди пардохти қабулшуда: T/T, Western Union; PayPal, Кафолати тиҷорат.
Забони гуфтугӯ: англисӣ.