Berberine Hydrochloride

Berberine hydrochloride, is an organic compound, chemical formula C20H18ClNO4, yellow crystalline powder, soluble in boiling water, slightly soluble in cold water, almost insoluble in cold alcohol, chloroform and ether, mainly used as antibacterial drugs, on dysentery bacillus, Escherichia coli, pneumococcus aureus, streptococcus, typhoid bacillus and amoeba have inhibitory effects. Clinical mainly used for intestinal infection and bacillary dysentery, also found that this product has anti-arrhythmia effect.

Appearance: yellow crystalline powder.

Solubility: easily soluble in boiling water, slightly soluble in cold water, almost insoluble in cold ethanol, chloroform and ether.

Berberine hydrochloride can effectively inhibit the proliferation of various cancer cells, promote apoptosis, and affect MAPK and Wnt/_beta_-catenin pathways.

Máme mnoho vysoce kvalitních továren s hlubokou spoluprací, které vám mohou poskytnout vysoce kvalitní produkty a konkurenceschopné ceny. A můžeme také poskytnout slevy na hromadné nákupy. A spolupracujeme s mnoha profesionálními spedičními společnostmi, dokážeme doručit produkty bezpečně a hladce do vašich rukou. Dodací lhůta je cca 3-20 dní po potvrzení platby.

pharmacodynamics
The antibacterial spectrum is wide, and it has antibacterial effect on many kinds of gram-positive and gram-negative bacteria in vitro, including hemolytic streptococcus, Staphylococcus aureus and Vibrio cholerae. Meningococcus, Shigella dysentery, typhoid bacillus, diphtheria bacillus have strong inhibitory effect, low concentration of bacteriostasis, high concentration of bactericidal. It also has certain inhibitory effect on influenza virus, amoeba, leptospira and some skin fungi. In vitro experiments show that berberine can enhance the phagocytosis of leukocyte and hepatic reticuloendothelial system. Dysentery bacillus, hemolytic streptococcus, staphylococcus aureus and so on are easy to develop resistance to this product. There is no cross-resistance between this product and penicillin, streptomycin, etc.

pharmacokinetics
Poor oral absorption. After injection, the drug quickly enters the organs and tissues, and the blood concentration is maintained for a short time. The blood concentration after intramuscular injection was lower than the minimum inhibitory concentration. Drugs are widely distributed, mainly in the heart, bone, lung and liver. The retention time in the tissue is short, only a trace amount remains after 24 hours, most of the drugs are metabolized and cleared in the body, and the discharge in its original form within 48 hours only accounts for less than 5% of the dose.

According to recent reports, it is believed that this product can reduce the number of pili on the surface of the body, so that the bacteria can not attach to the human cells, and play a therapeutic role. This product also has an effect on Helicobacter, and can relieve gastritis, gastric and duodenal ulcer.

1. Jste továrna nebo obchodní společnost?
Jsme společnost integrující průmysl a obchod a poskytujeme jednorázové služby. OEM lze přijmout.

2. Poskytujete vzorky? Je to zdarma nebo navíc?
Vzorky zdarma. Poplatek za dopravu vzorku musí být zaplacen vaší stranou.

3. Máte nějaké certifikáty týkající se kontroly kvality?
Certifikace ISO 9001:2008 pro zajištění kvality.

4. Co bych měl poskytnout, abych získal cenovou nabídku?
Pls, informujte nás o typu produktu, který potřebujete, množství objednávky, adresu a specifické požadavky. Cenová nabídka bude pro vaši referenci včas provedena.

5. Jaký způsob platby preferujete? Jaké podmínky jsou přijímány?
Přijaté dodací podmínky: FOB, CFR, CIF, EXW;
Přijatá měna platby:USD;
Přijímaný typ platby: T/T, Western Union; Paypal, Trade Assurance.
Mluvený jazyk: angličtina.