Omarigliptin

Product Name: Omarigliptin (MK-3102)
Synonyms: MK-3102;(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(2-(Methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)tetrahydro-2H-pyran-3-aMine;MK-3012;(2S,3R,5S)-2-(2,5-Difluorophenyl)-5-[2-(Methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-aMine (MK-3102 enantioMer);(2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine;OMarigliptin;OMarigliptin (MK-3102);2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine MK3102
CAS: 1226781-44-7
MF: C17H20F2N4O3S
MW: 398.43
EINECS: 682-558-0
Boiling point: 529.4±60.0 °C

Omarigliptin/MK-3102 is a potent, reversible, and competitive inhibitor of dipeptidyl peptidase 4 (DPP-4; IC50 = 1.6 nM; Ki = 0.8 nM). It is selective for DPP-4 over 168 proteas es, ion channels, and enzymes with IC50 values greater than 10 μM in all assays. MK-3102 significantly reduces blood glucose levels in a dose-dependent manner in vivo in rats. It also has a long half-life (11 and 22 hours in rat and dog, respectively) making it suitable for once weekly dosing. Clinical trials demonstrate that formulations containing MK-3102 reduce plasma glucose and HbA1c in patients with type 2 diabetes mellitus (T2DM).
Omarigliptin is a potent and selective dipeptidyl peptidase 4 (DPP-4) inhibitor to be used as treatment for type 2 diabetes

Tuna viwanda vingi vya ubora wa juu na ushirikiano wa kina, ambavyo vinaweza kukupa bidhaa za ubora wa juu na bei za ushindani. Na tunaweza pia kutoa punguzo kwa ununuzi wa wingi.Na tunashirikiana na makampuni mengi ya kitaalamu ya usambazaji wa mizigo, yanaweza kuwasilisha bidhaa kwa usalama na kwa urahisi mikononi mwako. Wakati wa uwasilishaji ni takriban siku 3-20 baada ya uthibitisho wa malipo.

1. Je, wewe ni kiwanda au kampuni ya biashara?
Sisi ni compnay kuunganisha sekta na biashara, kutoa one-stop service.OEM inaweza kukubalika.

2. Je, unatoa sampuli? Je, ni bure au ya ziada?
Sampuli zisizolipishwa. Ada ya mizigo ya sampuli inahitaji kulipwa na wewe.

3. Je, una vyeti vyovyote vinavyohusiana na udhibiti wa ubora?
Cheti cha ISO 9001:2008 ili kuhakikisha ubora.

4. Nitoe nini ili kupata nukuu?
Pls tufahamishe aina ya bidhaa unayohitaji, kiasi cha agizo, anwani na mahitaji maalum. Nukuu itafanywa kwa kumbukumbu yako kwa wakati.

5. Je, unapendelea njia gani ya malipo? Ni masharti ya aina gani yanakubaliwa?
Sheria na Masharti Yanayokubaliwa: FOB,CFR,CIF,EXW;
Sarafu ya Malipo Inayokubalika:USD;
Aina ya Malipo Yanayokubaliwa: T/T,Western Union; Paypal, Uhakikisho wa Biashara.
Lugha Inasemwa:Kiingereza.