Omarigliptin

99% Raw Material Omarigliptin Pharmaceutical Powder CAS 1226781-44-7

 

  • Aha ngwaahịa:

    Omarigliptin

  • Ọkwa:

    Ọkwa ọgwụ

  • Njirimara:

    ọcha ntụ ntụ

  • Nkwakọ ngwaahịa:

    25kg / agba

  • MOQ:

    1 kilo

  • Nchekwa:Ebe dị jụụ
  • Ndụ nchekwa:afọ 2


Nkọwa

Tags

Nkọwa ngwaahịa

Product Name: Omarigliptin (MK-3102)
Synonyms: MK-3102;(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(2-(Methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)tetrahydro-2H-pyran-3-aMine;MK-3012;(2S,3R,5S)-2-(2,5-Difluorophenyl)-5-[2-(Methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-aMine (MK-3102 enantioMer);(2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine;OMarigliptin;OMarigliptin (MK-3102);2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine MK3102
CAS: 1226781-44-7
MF: C17H20F2N4O3S
MW: 398.43
EINECS: 682-558-0
Boiling point: 529.4±60.0 °C

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Ngwa

Omarigliptin/MK-3102 is a potent, reversible, and competitive inhibitor of dipeptidyl peptidase 4 (DPP-4; IC50 = 1.6 nM; Ki = 0.8 nM). It is selective for DPP-4 over 168 proteas es, ion channels, and enzymes with IC50 values greater than 10 μM in all assays. MK-3102 significantly reduces blood glucose levels in a dose-dependent manner in vivo in rats. It also has a long half-life (11 and 22 hours in rat and dog, respectively) making it suitable for once weekly dosing. Clinical trials demonstrate that formulations containing MK-3102 reduce plasma glucose and HbA1c in patients with type 2 diabetes mellitus (T2DM).
Omarigliptin is a potent and selective dipeptidyl peptidase 4 (DPP-4) inhibitor to be used as treatment for type 2 diabetes

Uru

Anyị nwere ọtụtụ ụlọ ọrụ dị elu nke nwere nkwado miri emi, nke nwere ike inye gị ngwaahịa dị elu na ọnụ ahịa asọmpi. Anyị nwekwara ike inye ego maka nnukwu ịzụrụ ihe. Anyị na-akwado ọtụtụ ụlọ ọrụ na-ebuga ibu ndị ọkachamara, nwere ike ịnapụta ngwaahịa n'enweghị nsogbu na aka gị. Oge nnyefe bụ ihe dịka ụbọchị 3-20 mgbe nkwenye nke ịkwụ ụgwọ gasịrị.

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Nkọwapụta

BATCH NO.: HF171202

QUANTITY:75.1kg

---MFG. DATE : May., 2, 2024

SPECIFICATION: As required

REP. DATE : May.4, 2024

EXP. DATE : May.3, 2024

NGWA

STANDARDS

Nsonaazụ

Ọdịdị

White or off-white crystalline powder

Off-white crystalline powder

njirimara

By IR

Na-akwado

RT under chirality should complies

Na-akwado

Chloride: it gives a reaction of chloride

Na-akwado

Water

         3.0%~4.5%

3.4%

Melting Point-

198.0~202.0ºC

199.8~200.5ºC

Residue on Ignition

≤0.2%

0.08%

Heavy Metals

≤10ppm

Na-akwado

Related Substances

Individual Impurities:≤0.5%

0.15%

Total Impurities:≤1.0%

0.22%

Residual Solvent

≤0.06%

0.0066%

≤0.5%

0.015%

≤0.5%

0.0013%

E.E

≥99.0%

99.6%

Assay (on dry basis)

98.0%~102.0%

101.2%

Conclusion:It complies to prescribed enterprise standard.

 

Mbupu na ịkwụ ụgwọ

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FAQ

1. Ị bụ ụlọ ọrụ mmepụta ihe ma ọ bụ ụlọ ọrụ ịzụ ahịa?
Anyị bụ ụlọ ọrụ na-ejikọta ụlọ ọrụ na ịzụ ahịa, na-enye ọrụ nkwụsịtụ.OEM nwere ike ịnakwere.

2. Ị na-enye samples? Ọ bụ n'efu ka ọ bụ mgbakwunye?
Free samples. The sample si ibu ego kwesịrị ịkwụ ụgwọ gị n'akụkụ.

3. Ị nwere asambodo ọ bụla metụtara njikwa mma?
ISO 9001: 2008 asambodo iji hụ na ịdị mma.

4. Kedu ihe m ga-enye ka m nweta nhota okwu?
Pls na-agwa anyị ụdị ngwaahịa nke ị chọrọ, iji ọnụ ọgụgụ, adreesị na ihe ndị a chọrọ. A ga-edepụta nkwupụta maka ntinye aka gị n'oge.

5. Kedu ụdị usoro ịkwụ ụgwọ na-amasị gị? Kedu ụdị usoro anabatara?
Usoro nnyefe anabatara: FOB, CFR, CIF, EXW;
Ego ịkwụ ụgwọ anabatara: USD;
Ụdị ịkwụ ụgwọ anabatara: T/T, Western Union; Paypal, ahia ahia.
Asụsụ Asụsụ: Bekee.

 

Ọ bụrụ na ị nwere mmasị na ngwaahịa anyị, ị nwere ike ịhọrọ ịhapụ ozi gị ebe a, anyị ga-akpọtụrụ gị n'oge na-adịghị anya.


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