Camptothecin (CPT) is a cytotoxic quino line alkaloid which inhibits the DNA enzyme topoisomerase I (topo I). It was discovered in 1966 by M. E. Wall and M. C. Wani in systematic screening of natural products for anticancer drugs. It was isolated from the bark and stem of Camptotheca acuminata (Camptotheca, Happy tree), a tree native to China used as a cancer treatment in Traditional Chinese Medicine. CPT showed remarkable anticancer activity in preliminary clinical trials but also low solubility and (high) adverse drug reaction. Because of these disadvantages synthetic and medicinal chemists have developed numerous syntheses of Camptothecin and various derivatives to increase the benefits of the chemical, with good results. Two CPT analogues have been approved and are used in cancer chemotherapy today, topotecan and irinotecan.
1. Anti tumor effect.
2. Camptothecin can inhibit the proliferation of fibroblasts both in vivo and in vitro.
3. In addition, camptothecin has obvious inhibitory effect on herpesvirus.
4. In vivo, camptothecin is mainly excreted from bile and urine.
5. Camptothecin can induce chromosome aberration and is toxic.
6. Treatment of esophageal cancer, cardiac cancer.
7. Treatment of gastric cancer.
8. Treatment of primary liver cancer.
9. Treatment of psoriasis.
10. Treatment of skin warts.
Kami mempunyai banyak kilang berkualiti tinggi dengan kerjasama yang mendalam, yang boleh memberikan anda produk berkualiti tinggi dan harga yang kompetitif. Dan kami juga boleh memberi diskaun untuk pembelian pukal. Dan kami bekerjasama dengan banyak syarikat penghantaran barang profesional, boleh menghantar produk dengan selamat dan lancar ke tangan anda. Masa penghantaran adalah kira-kira 3-20 hari selepas pengesahan pembayaran.
Penampilan | Crystalline Powder | Mematuhi | Visual |
Color | Light Yellow | Mematuhi | Visual |
Bau | Characteristic | Mematuhi | Organoleptic |
Taste | Characteristic | Mematuhi | Organoleptic |
Particle Size 100 | 100% pass 80 mesh | Mematuhi | 80 Mesh Screen |
Kerugian pada Pengeringan | 5% Max | 3.21% | CPh |
Abu | 5%Max | 3.13% | CPh |
Part of Plant Used | Nut | Mematuhi | / |
Solvent Extract | Water | Mematuhi | / |
Excipient | 5%-10% Maltodextrin | Mematuhi | / |
Chemical Control | |||
Heavy metals | NMT10ppm | Akur | Atomic Absorption |
Arsenic (As) | NMT 2ppm | Akur | Atomic Absorption |
Mercury(Hg) | NMT 1ppm | Akur | Atomic Absorption |
Lead (Pb) | NMT 2ppm | Akur | Atomic Absorption |
GMO Status | GMO Free | Akur | / |
Solvent Residual | Meet E.P Standard | Akur | Ph.Eur |
Pesticides Residues | Meet USP Standard | Akur | Gas Chromatography |
Benzo(a)pyrene | NMT 10ppb | Akur | GC-MS |
Sum of benzo(a)pyrene, benz(a)anthracene, benzo(b)fluoranthene and chrysene | NMT 50ppb | Akur | GC-MS |
Microbiological Control | |||
Jumlah Kiraan Plat | 10000cfu/g Max | Akur | AOAC |
Yeast & Mold | 300cfu/g Max | Akur | AOAC |
S. aureus | Negatif | Negatif | AOAC |
E coli | Negatif | Negatif | AOAC |
Salmonella | Negatif | Negatif | AOAC |
Pseudomonas aeruginosa | Negatif | Negatif | USP |
1. Adakah anda sebuah kilang atau syarikat perdagangan?
Kami adalah syarikat yang menggabungkan industri dan perdagangan, menyediakan perkhidmatan sehenti. OEM boleh diterima.
2. Adakah anda menyediakan sampel? Adakah ia percuma atau tambahan?
Sampel percuma. Bayaran pengangkutan sampel perlu dibayar oleh pihak anda.
3. Adakah anda mempunyai sebarang sijil berkaitan kawalan kualiti?
Pensijilan ISO 9001:2008 untuk memastikan kualiti.
4. Apakah yang perlu saya sediakan untuk mendapatkan sebut harga?
Sila maklumkan kepada kami jenis produk yang anda perlukan, kuantiti pesanan, alamat dan keperluan khusus. Sebut harga akan dibuat untuk rujukan anda tepat pada masanya.
5. Apakah jenis kaedah pembayaran yang anda suka? Apakah jenis syarat yang diterima?
Syarat Penghantaran yang Diterima: FOB,CFR,CIF,EXW;
Mata Wang Bayaran Diterima:USD;
Accepted Payment Type: T/T,Western Union; Paypal,BTC
Bahasa Pertuturan:Bahasa Inggeris.
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