hygromycin A CAS 6379-56-2

Aminoglycosides are the most widely used class of antibiotics that target ribosome. Hygromycin B is an aminocyclitol antibiotic. The organism, S. hygroscopicus contains phosphotransferase (HPH) activity, which phosphorylates hygromycin B helping in autoimmunity against the toxic effects of the drug.

Hygromycin A is an aminoglycoside antibiotic isolated from Streptomyces hygroscopicus. It has been used to study protein synthesis at the level of the 70S ribosome translocation and mRNA template misreading, as an antiviral agent by selectively penetrating cells rendered permeable by virus infection and inhibiting translation, and as a selection agent for hygromycin resistance gene transformed cells.

Hygromycin A, a neglected antibiotic, selectively kills the bacteria that cause Lyme disease. It was able to treat Lyme disease in mice without disrupting the microbiome.Medicine (broad-spectrum antibiotic).

Medicine (broad-spectrum antibiotic).

Me gelek kargehên kalîteya bilind bi hevkariyek kûr heye, ku dikarin ji we re hilberên kalîteya bilind û bihayên reqabetê peyda bikin. Û em dikarin ji bo kirînên mezin erzanan jî bidin. Û em bi gelek pargîdaniyên barkêş ên profesyonel re hevkariyê dikin, dikarin hilberan bi ewlehî û bi aramî radestî destên we bikin. Dema radestkirinê piştî pejirandina dravdanê 3-20 rojan e.

Product Name:	hygromycin A
Synonyms:	hygromycin A;5-Deoxy-5-[[(2E)-3-[4-[(6-deoxy-β-D-arabino-5-hexosulofuranosyl)oxy]-3-hydroxyphenyl]-2-methyl-1-oxo-2-propenyl]amino]-1-O,2-O-methylene-D-neo-inositol;Antibiotic WS-1627B;D-neo-Inositol, 5-deoxy-5-[[(2E)-3-[4-[(6-deoxy-β-D-arabino-hexofuranos-5-ulos-1-yl)oxy]-3-hydroxyphenyl]-2-methyl-1-oxo-2-propen-1-yl]amino]-1,2-O-methylene-;Homomycin;Hygromycin;Homomycin A;(E)-N-[(3aS,4R,5R,6S,7R,7aR)-4,6,7-trihydroxy-3a,4,5,6,7,7a-hexahydro-1,3-benzodioxol-5-yl]-3-[4-[(2S,3S,4S,5S)-5-acetyl-3,4-dihydroxyoxolan-2-yl]oxy-3-hydroxyphenyl]-2-methylprop-2-enamide
CAS:	6379-56-2
MF:	C23H29NO12
MW:	511.48
EINECS:	608-965-5
Product Categories:
Mol File:	6379-56-2.mol

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