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hygromycin A CAS 6379-56-2

hygromycin A CAS 6379-56-2

 

  • Product name:

    hygromycin A CAS 6379-56-2

  • Grade:

    Pharmaceutical grade/Cosmetic grade

  • Properties:

    white powder

  • Packing:

    25kg/drum

  • MOQ:

    1 kilo

  • Storage:Cool Dry Place
  • Shelf life:2 years


Details

Tags

Product Description

Aminoglycosides are the most widely used class of antibiotics that target ribosome. Hygromycin B is an aminocyclitol antibiotic. The organism, S. hygroscopicus contains phosphotransferase (HPH) activity, which phosphorylates hygromycin B helping in autoimmunity against the toxic effects of the drug.

Application

Hygromycin A is an aminoglycoside antibiotic isolated from Streptomyces hygroscopicus. It has been used to study protein synthesis at the level of the 70S ribosome translocation and mRNA template misreading, as an antiviral agent by selectively penetrating cells rendered permeable by virus infection and inhibiting translation, and as a selection agent for hygromycin resistance gene transformed cells.

Hygromycin A, a neglected antibiotic, selectively kills the bacteria that cause Lyme disease. It was able to treat Lyme disease in mice without disrupting the microbiome.Medicine (broad-spectrum antibiotic).

Medicine (broad-spectrum antibiotic).

 

Advantages

We have many high-quality factories with deep cooperation, which can provide you with high quality products and competitive prices. And we can also give discounts for bulk purchases.And we cooperate with many professional freight forwarding companies, can deliver products safely and smoothly to your hands. Delivery time is about 3-20 days after confirmation of payment.

 

Specification
Product Name: hygromycin A
Synonyms: hygromycin A;5-Deoxy-5-[[(2E)-3-[4-[(6-deoxy-β-D-arabino-5-hexosulofuranosyl)oxy]-3-hydroxyphenyl]-2-methyl-1-oxo-2-propenyl]amino]-1-O,2-O-methylene-D-neo-inositol;Antibiotic WS-1627B;D-neo-Inositol, 5-deoxy-5-[[(2E)-3-[4-[(6-deoxy-β-D-arabino-hexofuranos-5-ulos-1-yl)oxy]-3-hydroxyphenyl]-2-methyl-1-oxo-2-propen-1-yl]amino]-1,2-O-methylene-;Homomycin;Hygromycin;Homomycin A;(E)-N-[(3aS,4R,5R,6S,7R,7aR)-4,6,7-trihydroxy-3a,4,5,6,7,7a-hexahydro-1,3-benzodioxol-5-yl]-3-[4-[(2S,3S,4S,5S)-5-acetyl-3,4-dihydroxyoxolan-2-yl]oxy-3-hydroxyphenyl]-2-methylprop-2-enamide
CAS: 6379-56-2
MF: C23H29NO12
MW: 511.48
EINECS: 608-965-5
Product Categories:  
Mol File: 6379-56-2.mol
hygromycin A Structure
 
hygromycin A Chemical Properties
Melting point  105-109°; mp 110-112° (dec) (Chida)
alpha  D25 -126° (c = 1 in water)
Boiling point  925.5±65.0 °C(Predicted)
density  1.60±0.1 g/cm3(Predicted)
storage temp.  -20°C
solubility  DMF: 16 mg/mL,DMSO: 10 mg/mL,Ethanol: 12 mg/mL,PBS (pH 7.2): 10 mg/mL
form  A solid
pka 8.9(at 25℃)
color  White to light yellow

 

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We are a compnay integrating industry and trade,providing one-stop service.OEM could be accepted.

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Free samples.The sample's freight fee need to be paid by your side.

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