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NADOLOL CAS 42200-33-9

NADOLOL CAS 42200-33-9

 

  • Product name:

    NADOLOL CAS 42200-33-9

  • Grade:

    Pharmaceutical/Cosmetic grade

  • Properties:

    white powder

  • Packing:

    25kg/drum

  • MOQ:

    1 kilo

  • Storage:Cool Dry Place
  • Shelf life:2 years


Details

Tags

Product Description

Nadolol is a non-selective beta-adrenergic receptor antagonist with antihypertensive and antiarrhythmic activity. White crystalline powder. Melting point 124-136℃, soluble in alcohol, slightly soluble in chloroform, insoluble in acetone, benzene.

 

Application

- Nadolol is a long-acting non-selective β-blocker with no intrinsic sympathetitic activity and membrane stabilization, and its β-receptor blocking strength is 3 to 9 times that of propranolol, which is a powerful antiarrhythmic drug. Nadolol can block the myocardial β1 receptor, produce negative frequency, negative Chemicalbook conduction, negative muscle strength of the three negative effects, but also block the airway and vascular smooth muscle β2 receptor, can reduce the rest and exercise systolic and diastolic blood pressure, 40mg or 80mg per tablet, the initial dose of 20~40mg. The usual dosage is 40~80mg/d.
- Antiarrhythmic drugs. Nadolol is used to treat high blood pressure, angina, arrhythmia, migraine, hyperthyroidism.

 

Advantages

We have many high-quality factories with deep cooperation, which can provide you with high quality products and competitive prices. And we can also give discounts for bulk purchases.And we cooperate with many professional freight forwarding companies, can deliver products safely and smoothly to your hands. Delivery time is about 3-20 days after confirmation of payment.

 

Specification
Product Name: NADOLOL
Synonyms: 1-(tert-butylamino)-3-((5,6,7,8-tetrahydro-cis-6,7-dihydroxy-1-naphthyl)oxy);1-(tert-Butylamino)-3-((5,6,7,8-tetrahydro-cis-6,7-dihydroxy-1-naphthyl)oxy)-2-propanol;1-(tert-bytylamino)-3-((5,6,7,8-tetrahydro-cis-6,7-dihydroxy-1-naphthyl)oxy)-2;2,3-cis-1,2,3,4-tetrahydro-5-((2-hydroxy-3-tert-butylamino)propoxy)-2,3-naph;2,3-cis-1,2,3,4-Tetrahydro-5-((2-hydroxy-3-tert-butylamino)propoxy)-2,3-naphthalenediol;2,3-cis-1,2,3,4-tetrahydro-5-(2-hydroxy-3-(tert-butylamino)propoxy)-2,3-naphth;2,3-diol;2,3-Naphthalenediol, 5-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-1,2,3,4-tetrahydro-
CAS: 42200-33-9
MF: C17H27NO4
MW: 309.4
EINECS: 255-706-3
Product Categories: RITALIN
Mol File: 42200-33-9.mol
NADOLOL Structure
 
NADOLOL Chemical Properties
Melting point  125-130°C
Boiling point  449.67°C (rough estimate)
density  1.0449 (rough estimate)
refractive index  1.5420 (estimate)
storage temp.  Refrigerator
solubility  Slightly soluble in water, freely soluble in ethanol (96 per cent), practically insoluble in acetone.
pka 9.67(at 25℃)
form  Solid
color  White to Off-White
Water Solubility  8.30g/L(25 ºC)

 

 

Shipping and payment

 

 

Features

1. Are you a factory or a trading company?
We are a compnay integrating industry and trade,providing one-stop service.OEM could be accepted.

2. Do you provide samples? Is it free or extra?
Free samples.The sample's freight fee need to be paid by your side.

3. Do you have any certificates related to quality control?
ISO 9001:2008 certification to ensure quality.

4. What should I provide to get a quotation?
Pls inform us of the product type which you need,order quantity,address and specific requirements.The quotation will be made for your reference in time.

5. What kind of payment method do you prefer? What kind of terms are accepted?
Accepted Delivery Terms: FOB,CFR,CIF,EXW;
Accepted Payment Currency:USD;EUR
Accepted Payment Type: T/T,Western Union; Paypal,Trade Assurance.
Language Spoken:English.

 

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