D-Biotin (Vitamin H)

D-Biotin, also known as vitamin H and coenzyme R, is a water-soluble vitamin and also belongs to the B vitamin group, B7. It is essential for the synthesis of vitamin C and is indispensable for the normal metabolism of fats and proteins. It is a necessary nutrient to maintain the human body's natural growth, development and normal human function and health.

D-Biotin is one of the B vitamins, also known as vitamin H, vitamin B7, Coenzyme R and so on. In the 1930s, while studying yeast growth factor and rhizobia growth and respiration promotion factor, it was discovered from the liver that could prevent hair loss and skin damage in rats induced by feeding raw egg protein. Biotin is a member of the water-soluble B vitamin group. It is more abundant in liver, kidney, yeast and milk, and is an important factor for the fixation of carbon dioxide by organisms. It is easy to bind with a protein in egg white, and a large amount of raw protein can hinder the absorption of biotin leading to biotin deficiency, such as hair removal, weight loss, dermatitis and so on. Biotin plays an important role in biochemical pathways such as fat synthesis and glycogenesis.

D-Biotin is the savior of bald people. It not only prevents hair loss and light on the top of the head, but also prevents juvenile white hair which is common in modern people. It also plays an important role in maintaining skin health. As for the effect of calming the nervous system has not been proven, but it does help with depression and insomnia.

D-Biotin is a coenzyme of many carboxylases and acts as a CO2 carrier in carboxylase reaction.

Physiological effects: Biotin combined with enzymes participate in the fixation and carboxylation of carbon dioxide in the body, which is related to important metabolic processes in the body, such as the carboxylation of pyruvate into oxaloacetic acid, and the carboxylation of acetyl-CoA into malonyl-CoA and other major biochemical reactions in the metabolism of sugar and fat. It is also a growth factor for some microorganisms, and an extremely small amount (0.005 micrograms) can make the tested bacteria grow. For example, Streptospora requires very small amounts of biotin to grow. The human body needs about 100 to 300 micrograms per day. There is an antibiotin protein in raw egg white that can bind to biotin, and the combined biotin cannot be absorbed by the digestive tract. Resulting in animal body biotin deficiency, this time there is loss of appetite, glossitis, dander dermatitis, hair removal and so on. However, no human cases of biotin deficiency have been reported, possibly due to the ability of gut bacteria to synthesize biotin in addition to food sources.

Function: Vitamin H is a key regulatory element for the heterogenesis of glycogen, the combined action of fatty acids, and the metabolism of certain amino acids, and can promote the synthesis of certain proteins by assisting in energy production; At the same time, it can assist cell growth, manufacture fatty acids, metabolize sugars, fats and proteins, and contribute to the utilization of vitamin B groups; Promote the health of sweat glands, nervous tissue, bone marrow and male gonads; Maintain the normal operation and growth of skin and hair, reduce the symptoms of eczema and dermatitis; Prevent white hair and hair loss, help to treat baldness; Relieve muscle pain; It is certainly helpful for depression and insomnia; Also involved in vitamin B12, folic acid, pantothenic acid metabolism; Promote urea synthesis and excretion; Improve the body's immune function.

Biotin, also known as vitamin H, enables the body to convert food into energy. Biotin is beneficial to cell health and regeneration. People with diabetes can improve blood sugar regulation through biotin. Biotin is also needed for the health of hair and nails.

Health use
diabetes. Biotin supplements, biotin helps improve blood sugar regulation by improving insulin and blood sugar use.

Hair and nails. Biotin supplements can repair weak and burst toenails and fingernails and improve the health of your hair. Biotin can also repair premature greying of hair caused by low biotin levels.

Genetic problems; Some babies do not make good use of biotin and need to take biotin supplements.

Skin problems; Some skin conditions, such as breast scabs, can be improved with biotin supplementation.

Muscular dystrophy; Biotin can be used to treat certain muscle-related diseases as part of a course of treatment.

Nutritional health; Biotin can help people lose weight to have a more efficient metabolism.

Infectious diseases; Biotin can be used to treat intestinal candida (a yeast infection).

According to studies, the combination of folic acid and biotin can effectively prevent the formation of teratogenesis. In early 2008, the Japanese Ministry of Health and Welfare has officially announced that biotin and folic acid are mandatory intake nutrients for pregnant women in Japan. It is certain that this decision of the Ministry of Health and Welfare will greatly promote the sales of biotin in Japan, and at the same time, will further promote the consumption of biotin worldwide.

American researchers also found that biotin can promote the breakdown of fats and carbohydrates, so that they speed up the conversion of energy needed for human activities; If the amount of biotin in the body is insufficient, fat will accumulate in the body and cause obesity. This new discovery lays a solid foundation for the application of biotin in weight loss and slimming health products, and opens up a broader market for biotin.

Cosmetic use
At the same time, Japanese scholars also reported that biotin has an excellent cosmetic effect, which can keep the skin white and nails smooth. The discovery also opens up a new pharmaceutical use for biotin products. The beauty and cosmetics industry is one of the big international industries, the total sales of beauty and cosmetics in the international market is much higher than the sales of drugs, and the new application of biotin in skin beauty, nail (nail) and hair will lead to the increase of sales of pharmaceutical biotin.

As a drug, it is used to treat arteriosclerosis, stroke, lipid metabolism disorders, hypertension, coronary heart disease and blood circulation disorders.

Used in cosmetics, it can improve the speed of blood circulation in the skin blood vessels, in the concentration range of 0.1% to 1.0%, easy to mix the oil phase in the formula. It can be used in skin care cream, sports medicine, pain relief cream for feet, shaving liquid and shampoo.

Scientific research use
Biotin can be used as a marker for nucleic acid probes, which can bind to the UTP or dUTP 5 'C of nucleic acid molecules, and can be detected by binding to avidin. In the detection process, biotin is only used as a fixed connection, not as a signal detection.

ພວກເຮົາມີໂຮງງານທີ່ມີຄຸນນະພາບສູງຫຼາຍທີ່ມີການຮ່ວມມືຢ່າງເລິກເຊິ່ງ, ເຊິ່ງສາມາດໃຫ້ທ່ານຜະລິດຕະພັນທີ່ມີຄຸນນະພາບສູງແລະລາຄາທີ່ແຂ່ງຂັນ. ແລະພວກເຮົາຍັງສາມາດໃຫ້ສ່ວນຫຼຸດສໍາລັບການຊື້ຈໍານວນຫລາຍ.ແລະພວກເຮົາຮ່ວມມືກັບບໍລິສັດຂົນສົ່ງສິນຄ້າມືອາຊີບຈໍານວນຫຼາຍ, ສາມາດຈັດສົ່ງຜະລິດຕະພັນໄດ້ຢ່າງປອດໄພແລະກ້ຽງກັບມືຂອງທ່ານ. ເວລາສົ່ງແມ່ນປະມານ 3-20 ມື້ຫຼັງຈາກຢືນຢັນການຈ່າຍເງິນ.

Recommended daily intake: Adults are recommended to take 25 to 300μg per day. Biotin works better when used with vitamins (vitamin food) A, B2, B6, and niacin.
Supplement cycle: Vitamin B7 only stays in the body for 3 to 6 hours, so it must be supplemented every day.
People who need: People who eat raw eggs and drink alcohol need to supplement biotin; People taking antibiotics or sulfonamides should take at least 25μg per day; Men with sparse hair (male food) intake of biotin, prevent hair loss effect is obvious; During pregnancy, biotin will be significantly lost and should be reasonably supplemented under the guidance of a physician.
Biotin (Vitamin H) deficiency: Biotin (Vitamin H) Biotin (vitamin H) deficiency is mainly manifested by skin symptoms, such as thinning hair, loss of luster, dry skin, scaly dermatitis, red rash, and in severe cases the rash can continue around the eyes, nose and mouth. In addition, it was accompanied by loss of appetite, nausea, vomiting, tongue and nipple atrophy, mucous membrane gray, numbness, mental depression, fatigue, myalgia, hypercholesterolemia and EEG abnormalities. Most of these symptoms occur after 10 weeks of biotin (vitamin H) deficiency. Seborrheic dermatitis may occur in infants under 6 months of age.
Biotin (vitamin H) overexpression: The toxicity of biotin (vitamin H) is very low, and no toxic effects of biotin (vitamin H) have been reported.
dietary nutrient reference intakes (DRI) suggest that the daily dose of biotin is 30 μg. Normal blood biotin concentration is 133~329 pmol/L, if the dose of biotin is too large, long-term use of some cases can induce acne, facial stiffness, muscle weakness and so on.

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