Bilirubin

Bilirubin is a kind of bile pigment, which is the main pigment in human bile. Bilirubin is the main metabolite of iron porphyrin compounds in the body, which is toxic and can cause irreversible damage to the brain and nervous system, but also has antioxidant functions and can inhibit the oxidation of linoleic acid and phospholipids. Bilirubin is an important basis for clinical diagnosis of jaundice and an important index of liver function.

Bilirubin is a pigment produced by the hemoglobin in red blood cells, which have a fixed lifespan (the average lifespan of normal red blood cells is about 120 days) and are destroyed daily. At this point, the hemoglobin is broken down into methemohemin and heme. Under the action of NADPH and H ions, hematin produces biliverdin, trivalent Fe ions and CO, and biliverdin produces bilirubin under the action of NADPH and H ions. The heme is remade into histamin.

Bilirubin can help the liver to remove waste material, help fat metabolism, fight free radicals, promote blood circulation and protect the nervous system, etc. Details are as follows:

1. It can help the liver remove waste materials: Bilirubin is a pigment produced by the liver, which can bind and remove waste materials and toxins from the body.

2. Helps with fat metabolism: Bilirubin is involved in fat metabolism in the body and can help the body break down fat and convert it into energy.

3. Fighting free radicals: Bilirubin has an antioxidant effect, which can neutralize free radicals in the body and reduce their damage to cells.

4. Promote blood circulation: Bilirubin can increase the activity of vascular endothelial cells, promote blood circulation, and help maintain heart and blood vessel health.

5. Protect the nervous system: Bilirubin protects nerve cells from oxidative stress and reduces the risk of neurological diseases such as Alzheimer's and Parkinson's disease.

It should be noted that bilirubin is beneficial to the human body at a certain concentration, but too high bilirubin levels can cause diseases such as jaundice. Therefore, maintaining normal bilirubin metabolism and excretion is an important factor in maintaining health.

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Bilirubin is a kind of bile pigment of Dimethyl bile pigment. It is a red brown pigment body, insoluble in water, insoluble in alcohol, ether, and easily soluble in alkali. The maximum absorption is 432 nm (alkali) and 540 nm (chloroform). Bile is abundant in humans and carnivores. There are two types of blood bilirubin in the red-purple Hijman van den Bergh reaction with the addition of diazo reagents: one is the direct type that appears positive without alcohol, and the other is the indirect type that shows color with alcohol. The first type is mono - or bisglucuronic acid (ester), the second is free, is a normal metabolite of hemoglobin, can be formed by the reduction of biliverdin, such as further reduction, by vinyl to ethyl mesobilubin C30H40O6N, methymethylate is fully saturated with hydrogen, forming mesobilane (urobilinogen).

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