Leonurine Hydrochloride

Motherwort has the ability to act as a galactagogue, meaning it promotes a mother's milk flow.it also has been used as a uterine tonic before and after childbirth. the herb contains a chemical
called leonurine, which encourages uterine contractions. Motherwort is also claimed to be an emmenagogue, or an agent that promotes menstrual flow. it has been used for centuries to
regulate the menstrual cycle and to treat menopausal and menstrual complaints.

• One of the more famous traditional uses of motherwort is to help regulate irregular heart rates caused by anxiety and stress. Studies have shown it to have anti-arrhythmic effects which can help regulate heart rates and lower increased heart rates.

• A small trial using Motherwort oil showed significant improvements in blood pressure readings, heart rate, and ECG as well as an improvement in anxiety, sleep and headaches.

• Motherwort has a weak calcium channel blocker action, furthering its benefits in high blood pressure.

• It contains a specific chemical called leonurine which is an alkaloid with a wide range of biological activity including vasodilation, muscle relaxant, anti-oxidation, anti-inflammation, and anti-apoptosis. (cell death)

• An alkaloid called Stachydrine is found in Motherwort, which has been shown to protect endothelial function

• Motherwort is rich in bioactive flavonoids. Large observational studies have shown a link between a persons total flavonoid intake and their risk of heart disease. Higher flavonoid intakes lead to a reduced risk of heart disease.

• A rich source of anti-oxidants which are known to lower cardiovascular disease morbidity and mortality.

1.For treatment of irregular menstruation caused by stasis in the blood division of women, dysmenorrhea, amenorrhea
2. For treatment of edema, difficulty in urination with stagnant heat.
3. It can also be used to treat skin sore and carbuncle caused by
noxious heat, by its effect of clearing away heat and toxins.
4. To treat amenorrhea (abnormal absence or suppression of menses),
dysmenorrhea (painful menstruation) and obstructed menstruation due
to blood stasis, postpartum abdominal pain due to blood stasis and qi stagnation, etc.
5. Increases cardiac circulation.
6. Eases gastrointestinal distress.
7. Relieves discomfort associated with premenstrual syndrome.

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Motherwort extract is the above-ground part of Leonurus heterophyllus Sweet, a plant of the Lamiaceae family. It has the functions of promoting blood circulation, regulating menstruation, removing blood stasis and regenerating new life, diuresis and swelling, and clearing away heat and detoxification.

The whole plant contains Leonurine (Leonurine) about 0.05% (a trace amount at the beginning of the flower, and gradually increases during the flowering period), Stachydrine, Rutin, Fumaric acid (Fumaric acid), Leonurine, 4-Arginine, 4-Arginine, Arginine, Fragrant, Stigmasterol and Sitosterol. 5 kinds of crystalline substances: Leonurusine A, Leonurusine B and Leonurus A, B and C. The flowers contain leonuridine.

1. Effect on the uterus: Motherwort has obvious excitatory effect on the uterus, manifested by increased uterine tension, increased contraction amplitude, and faster rhythm. It can significantly increase the contraction of uterine muscles, and its effect is similar to that of the posterior pituitary hormone.
2. Effects on the cardiovascular system:
(1) It has the effect of strengthening the heart, increasing coronary flow and myocardial nutritional blood flow;
(2) It can slow down the heart rate, resist experimental myocardial ischemia and arrhythmia, resist angina pectoris, and reduce the scope of myocardial infarction;
(3) It has an inhibitory effect on platelet aggregation, thrombosis and red blood cell aggregation;
(4) It can dilate blood vessels and have a short-term antihypertensive effect.
3. Effect on the urinary system: Motherwort can treat acute renal failure, Motherwort can improve kidney function, and Motherwort has obvious diuretic effect.
4. The effect on the central nervous system: it has a direct excitatory effect on the respiratory center, but in large doses, the respiration changes from excitement to inhibition, and becomes weak and irregular.
5. Other functions: It has the functions of enhancing the immune system and inhibiting bacteria.

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