Carbomer 940 ua

Carbomer copolymer tuaj yeem siv los ua cov khoom siv ntxiv, xws li bioadhesives, emulsifiers, tso tawm modifiers, tshem tawm cov neeg ua haujlwm, cov ntsiav tshuaj nplaum, viscosifiers, thiab lwm yam. Pharmaceutical excipients lossis pharmaceutical auxiliaries yog xa mus rau lwm yam tshuaj lom neeg, uas tsis yog cov khoom siv tshuaj, siv rau hauv cov txheej txheem tshuaj. Pharmaceutical excipients feem ntau xa mus rau cov khoom xyaw tsis muaj zog hauv kev npaj tshuaj, uas tuaj yeem txhim kho kev ruaj ntseg, solubility thiab kev ua tiav ntawm kev npaj tshuaj. Pharmaceutical excipients tseem cuam tshuam rau kev nqus, faib, metabolism, thiab tshem tawm (ADME) cov txheej txheem ntawm cov tshuaj sib koom ua ke.

Cov khoom tso saib

1. 1.Carbomer 940 yog cov hmoov dawb dawb; Acid, hygroscopic thiab me ntsis tsw tshwj xeeb, soluble hauv dej, ethanol, glycerol. Cov concentration ntau yog 0.1% ~ 3.0%. Vim tias nws cov molecules muaj ntau pawg carboxyl, tshwj xeeb yuav tsum tau them nyiaj rau kev siv cov tshuaj aqueous tom qab neutralization nrog alkali kom txo tau qhov khaus ntawm daim tawv nqaij thiab mucous daim nyias nyias.

2. 2.Tus neeg sawv cev nruab nrab ntawm carbomer 940 tuaj yeem yog sodium hydroxide, potassium hydroxide, potassium bicarbonate, borax, amino acids, polar organic amines xws li triethanolamine. Lauramine thiab stearamine tuaj yeem siv los ua cov tshuaj nruab nrab hauv cov tshuab tsis-polar.

3. 3.Carbomer 940 nws tus kheej tsis ncaj qha muab tshuaj tua kab mob thiab ua kom tsis muaj menyuam, nws yog los ntawm kev ncua lub sijhawm cawv nyob ntawm daim tawv nqaij kom ntxiv dag zog rau cov tshuaj tua kab mob thiab ua kom tsis muaj menyuam, thiab tuaj yeem ua rau cov khoom muaj qhov zoo ntawm daim tawv nqaij, Carbomer 940 gel tsis ruaj khov, yooj yim. kom loj hlob pwm thiab poob viscosity sai sai thaum raug tshav ntuj, ntxiv antioxidant tuaj yeem ua rau cov tshuaj tiv thaiv qeeb.

4. 4.Carbomer 940 pob tshab: Qhov sib ntxiv ntawm cov muaj zog hydrophilic non-electrolyte (xws li ethanol) yuav ua rau cov tshuaj polymer flocculate. Cov txheej txheem kev ua haujlwm sib txawv yuav npaj Carbomer ethanol gel, thiab qhov kev txwv siab ntawm ethanol concentration ntawm cov khoom tiav yuav txawv. Thaum cov ethanol concentration siab dhau lawm, cov gel tiav lawm yuav tsim me ntsis opalescence thiab txo cov gel pob tshab.

5. 5.Carbomer 940 viscosity: Lub degree ntawm molecular kev loj hlob, PH nqi, electrolyte concentration yuav cuam tshuam lub viscosity ntawm Carbomer 940, tom qab neutralization, Carbomer hydrogel yog viscous tshaj pH6 thiab 11, yog pH <3 los yog pH> 12, lub viscosity. txo. Lub xub ntiag ntawm cov electrolyte muaj zog tuaj yeem txo cov viscosity.

6. 6.Carbomer 940 yog rhiab heev rau cov ntsev thiab cations, thiab tus nqi ntawm cov khoom no yuav tsum tau tswj thaum lub concentration ntawm soluble ions nyob rau hauv cov khoom ntau tshaj 0.1%. Yog tias ua tau, cov khoom siv acidic, nruab nrab lossis alkaline yog siv los ua cov tshuaj tseem ceeb substrate, cov dej deionized yog siv, thiab ntsev ntxiv tom qab neutralization kom nkag siab txog qib ntsev ntawm lub cev. Tus nqi siab ions (Ca, Mg, Fe, AI) yuav ua rau muaj kev puas tsuaj loj rau lub cev thiab yuav tsum tau muab tshem tawm.

7. 7.Packing: tuaj yeem muab ntim rau hauv cov hnab yas tsis muaj dej noo thiab huab cua nruj, thiab tom qab ntawd ntim rau hauv lub thawv ntawv. Carbomer muaj cov khoom muaj zog hygroscopic. Thaum khaws cia, nco ntsoov xyuam xim rau kev sib khi, ceev faj ntawm cov khoom nqus dej noo hauv huab cua, yog tias muaj me ntsis clumps, maj mam pat, uas tuaj yeem ua cov hmoov xoob, yuav tsis cuam tshuam rau cov nyhuv thickening. Thaum qhib, tso rau hauv ib lub thawv airtight nrog lub desiccant.

Carbomer 940 feem ntau yog siv hauv emulsion, gel thiab lwm yam khoom siv dej. Nws tuaj yeem ua rau kom muaj viscosity thiab sib xws ntawm cov khoom thiab muab cov khoom zoo dispersion thiab stability.

Cov chaw tsim khoom uas peb koom tes nrog muaj kev xa khoom loj ntawm Carbomer 940, xa khoom sai thiab hnub tsim khoom tshiab. Qhov no tuaj yeem pab qee tus neeg muag khoom thiab cov neeg yuav khoom kom yuav cov khoom zoo Carbomer 940 nrog cov hnub tsim khoom tshiab los ntawm peb. Peb yuav tsis muag cov khoom nyob ze rau hnub tas sij hawm rau cov neeg siv khoom zoo li lwm tus, vim tias kev thauj mus los yuav siv sij hawm, yog li peb lub sijhawm xa khoom feem ntau yog teem rau hauv 10-15 hnub, thiab kev txiav txim qis dua 10 tons yuav raug xa tawm hauv 10 hnub.

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Daim ntawv pov thawj ntawm Kev tsom xam-- Carbomer 940

Carbomer 940 yog ib qho tshuaj siv dav siv rau kev kho mob ntawm cov kab mob hauv lub paj hlwb uas nws cov txiaj ntsig tseem ceeb yog txhawm rau txhim kho cov paj hlwb los ntawm kev tswj hwm kev tso tawm ntawm cov neurotransmitters.

Lub luag haujlwm tseem ceeb ntawm carbomer 940 yog tswj kev tso tawm ntawm cov neurotransmitters, uas yog qhov tseem ceeb rau kev kho mob ntawm cov kab mob neurological. Neurotransmitters yog cov khoom tseem ceeb rau kev xa cov ntaub ntawv ntawm cov paj hlwb, thiab carbomer 940 tuaj yeem tswj kev tso tawm ntawm cov neurotransmitters, yog li txhim kho cov haujlwm ntawm cov paj hlwb thiab txo cov tsos mob ntawm tus kab mob.

Clinically, carbomer 940 feem ntau yog siv los kho qee cov kab mob neurological, xws li Parkinson's disease thiab Alzheimer's disease. Tus kab mob Parkinson yog ib hom kab mob hauv lub paj hlwb, cov neeg mob feem ntau tshwm sim nrog cov leeg mob, tshee thiab lwm yam tsos mob, carbomer 940 tuaj yeem txhim kho cov tsos mob zoo. Alzheimer's disease yog kab mob neurodegenerative uas cov neeg mob muaj kev nco tsis tau, txo kev xav thiab lwm yam tsos mob, thiab carbomer 940 tuaj yeem txhim kho cov tsos mob no los ntawm kev tswj kev tso tawm ntawm cov neurotransmitters.

Tsis tas li ntawd, carbomer 940 muaj kev phiv tsawg dua, tab sis txhua yam tshuaj yuav muaj kev cuam tshuam tsis zoo, yog li nws yuav tsum tau ua raws li thaum siv tus kws kho mob cov lus qhia, yog tias tsis muaj kev hloov pauv mus nrhiav kev kho mob.

Carbomer 940 yog ib qho tshuaj zoo rau kev kho mob ntawm cov kab mob hauv lub paj hlwb, thiab nws cov txheej txheem ntawm kev ua haujlwm feem ntau yog los txhim kho cov paj hlwb los ntawm kev tswj cov kev tso tawm ntawm cov neurotransmitters. Txawm li cas los xij, nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias kev siv cov tshuaj yuav tsum tau ua raws li tus kws kho mob cov lus qhia kom muaj kev nyab xeeb thiab ua tau zoo.