Ademetionine 1,4-Butanedisulfonate(SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissue including the liver, joints and brain.
1.Ademetionine 1,4-Butanedisulfonate(SAMe) is a coenzyme involved in methyl group transfers. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase (EC 2.5.1.6). Transmethylation, transsulfuration, and aminopropylation are the metabolic pathways that use SAMe. Although these anabolic reactions occur throughout the body, most SAMe is produced and consumed in the liver.
2.Ademetionine 1,4-Butanedisulfonate attached to the methionine sulfur atom in SAMe is chemically reactive. This allows donation of this group to an acceptor substrate in transmethylation reactions. More than 40 metabolic reactions involve the transfer of a methyl group from SAMe to various substrates such as nucleic acids, proteins, and lipids.
3.In bacteria, SAMe is bound by the SAMe riboswitch, which regulates genes involved in methionine or cysteine biosynthesis.
Peb muaj ntau lub Hoobkas zoo nrog kev koom tes sib sib zog nqus, uas tuaj yeem muab koj cov khoom zoo thiab cov nqi sib tw. Thiab peb tseem tuaj yeem muab cov luv nqi rau kev yuav khoom ntau.Thiab peb koom tes nrog ntau lub tuam txhab xa khoom xa tuaj, tuaj yeem xa cov khoom lag luam kom nyab xeeb thiab ntseeg nkaws rau koj txhais tes. Lub sij hawm xa tuaj yog li 3-20 hnub tom qab tau txais kev pom zoo ntawm kev them nyiaj.
Test Items | Specifications | Cov txiaj ntsig | |
Qhov tshwm sim | White to off-white Powder | White crystalline powder | |
HPLC | The retention time of the major peak corresponds to the reference sample | Complied |
|
Specific Rotation | +28°~+34° | +30 | |
Water | 3.0% MAX | 2.2% | |
PH (0.4% AQUEOUS SOLUTION) | 1.8 -2.5 | 2.2 | |
Residue on ignition | ≤ 0.5% | 0.3% | |
Heavy Metals | Not more than 10 ppm | Complied | |
Content of Ademetionine(HPLC) | 50.0 - 54.0% | 50.1% | |
Content of 1,4-butanedisulfonate | 46.0%-49.0% | 48.6% | |
S,S-isomer | ≥60% | 77.5% | |
Related substances(HPLC): | |||
- ADENINE | 0.5% MAX. | 0.1% | |
- S-ADENOSYL-L-HOMOCYSTEINE | 0.5% MAX. | 0.05% | |
- METHYLTHIOADENOSINE | 0.5% MAX. | 0.2% | |
OTHER INDIVIDUAL IMPURITY | 0.1% MAX. | 0.09% | |
- TOTAL OTHER IMPURITIES | 1.0% MAX. | 0.4% | |
- TOTAL IMPURITIES | 2.5% MAX. | 0.8% | |
ASSAY | ≥97.0% | 98.7% | |
Bacterual endtoxin | ≤0.25EU/mg | Complied | |
Microbiology |
Total Aerobic Count | ≤200cfu/g | Complied |
Total Combined Yeasts and Molds Count | ≤100cfu/g | Complied | |
E. coli | Absent/10g | Complied | |
Xaus | Complies with Enterprise standard |
1. Koj puas yog lub Hoobkas lossis tuam txhab lag luam?
Peb yog ib qho kev sib koom ua ke kev lag luam thiab kev lag luam, muab kev pabcuam ib-nres.OEM tuaj yeem txais.
2. Koj puas muab cov qauv? Puas yog dawb lossis ntxiv?
Cov qauv dawb.Cov qauv tus nqi thauj khoom yuav tsum tau them los ntawm koj sab.
3. Koj puas muaj daim ntawv pov thawj ntsig txog kev tswj xyuas zoo?
ISO 9001: 2008 ntawv pov thawj los xyuas kom meej qhov zoo.
4. Kuv yuav muab dab tsi kom tau txais cov lus hais?
Pls qhia peb txog cov khoom lag luam uas koj xav tau, xaj kom muaj nuj nqis, chaw nyob thiab cov kev xav tau tshwj xeeb.Cov lus hais yuav ua rau koj siv sijhawm.
5. Hom kev them nqi twg koj nyiam? Cov nqe lus twg raug lees txais?
Txais Cov Lus Cog Tseg: FOB, CFR, CIF, EXW;
Txais Nyiaj Them Nqi: USD;
Hom Kev Them Nyiaj: T / T, Western Union; Paypal, Trade Assurance.
Lus Hais: Lus Askiv.
Cov khoom qeb